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Evaluation and Management of Acute Stevens-Johnson Syndrome

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Ocular Surface Disease

Abstract

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are eruptive mucocutaneous blistering diseases that can yield severe scarring of the eyelids and ocular surface. This scarring frequently leads to significant consequences such as severe dry eye, photophobia, and decreased vision. The severe sequelae are difficult, if not impossible, to reverse and can lead to lifelong disability for the patients. When applied in the first week of the illness, amniotic membrane transplantation (AMT) has been shown to effectively and consistently prevent the more serious sequelae of SJS and TEN [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15]. The cases presented will explore various aspects of the ophthalmologic evaluation of acute SJS/TEN and decisions regarding the use of AMT in the acute phase of the disease, generally defined as the initial blistering portion of the disease that lasts anywhere from 2 to 4 weeks in most cases.

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Correspondence to Darren G. Gregory MD .

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Ciralsky, J.B., Sippel, K.C., Gregory, D.G. (2018). Evaluation and Management of Acute Stevens-Johnson Syndrome. In: Djalilian, A. (eds) Ocular Surface Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-15823-5_21

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  • DOI: https://doi.org/10.1007/978-3-319-15823-5_21

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-15822-8

  • Online ISBN: 978-3-319-15823-5

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