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Management of Limbal Stem Cell Deficiency

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Ocular Surface Disease

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Abstract

Limbal stem cell deficiency is one of the most visually significant ocular surface diseases. It rarely presents in isolation and is always associated with tear film dysfunction and inflammation which can be subclinical. The more severe cases likewise involve conjunctival and eyelid disease. A comprehensive treatment approach that addresses all of the associated diseases of the ocular surface is crucial for achieving long-term success. Of particular importance is improving the environment for the limbal stem cells, specifically the limbal niche. The following cases highlight the medical and surgical treatment options for patients with various etiologies and severity of limbal stem cell deficiency.

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Authors and Affiliations

  1. Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, 60607, USA

    Elham Ghahari MD, Duaa Sharfi MD & Ali R. Djalilian MD

  2. Cincinnati Eye Institute, University of Cincinnati, Cincinnati, OH, 45220, USA

    Edward J. Holland MD

Authors
  1. Elham Ghahari MD
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  2. Duaa Sharfi MD
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  3. Edward J. Holland MD
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  4. Ali R. Djalilian MD
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Corresponding author

Correspondence to Ali R. Djalilian MD .

Editor information

Editors and Affiliations

  1. Cornea Service, Illinois Eye and Ear Infirmary, Chicago, Illinois, USA

    Ali R. Djalilian

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© 2018 Springer International Publishing AG

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Ghahari, E., Sharfi, D., Holland, E.J., Djalilian, A.R. (2018). Management of Limbal Stem Cell Deficiency. In: Djalilian, A. (eds) Ocular Surface Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-15823-5_19

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  • DOI: https://doi.org/10.1007/978-3-319-15823-5_19

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-15822-8

  • Online ISBN: 978-3-319-15823-5

  • eBook Packages: MedicineMedicine (R0)

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