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Identification of Malignant Tumors in the Liver

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Fluorescence Imaging for Surgeons

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Abstract

To date, surgery is the only curative treatment option for patients with resectable metastases in the liver and is regarded as standard-of-care. However, recurrence rates remain high, which might partly be explained by the inability of conventional technologies to detect small lesions. Near-infrared fluorescence imaging is able to detect lesions as small as 1 mm, but only if they are localized on or several millimeters below the liver surface. Several studies reported the identification of otherwise undetectable liver tumors using near-infrared fluorescence imaging. Research in the coming years will have to determine if this technology is truly beneficial for patients requiring resection of malignant liver tumors.

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Authors and Affiliations

  1. Department of Surgery, Leiden University Medical Centre, Albinusdreef 2, Leiden, 2333ZA, The Netherlands

    Henricus J. M. Handgraaf M.D., Floris P. R. Verbeek M.Sc., Cornelis J. H. van de Velde M.D., Ph.D., Merlijn Hutteman M.D., Ph.D. & Alexander L. Vahrmeijer M.D., Ph.D.

Authors
  1. Henricus J. M. Handgraaf M.D.
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  2. Floris P. R. Verbeek M.Sc.
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  3. Cornelis J. H. van de Velde M.D., Ph.D.
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  4. Merlijn Hutteman M.D., Ph.D.
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  5. Alexander L. Vahrmeijer M.D., Ph.D.
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Corresponding author

Correspondence to Alexander L. Vahrmeijer M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Section of Minimally Invasive Surgery, Department of General and Vascular Surgery, The Bariatric and Metabolic Institute, Cleveland Clinic Florida, FL, USA; Oncological Surgical Division, Division of Surgical Research, Department of Surgery, Hospital de Clinicas Buenos Aires, University of Buenos Aires, Buenos Aires, Argentina

    Fernando D. Dip

  2. Department of Gastroenterological Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research; Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

    Takeaki Ishizawa

  3. Hepato-Biliary-Pancreatic Surgery; Department of Surgery, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan

    Norihiro Kokudo

  4. Department of General Surgery, Section of Minimally Invasive Surgery; Department of General and Vascular Surgery, The Bariatric and Metabolic Institute, Cleveland Clinic Florida, Weston, Florida, USA

    Raul J. Rosenthal

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Identification of metastatic liver cancer (MP4 11,961 kb)

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Handgraaf, H.J.M., Verbeek, F.P.R., van de Velde, C.J.H., Hutteman, M., Vahrmeijer, A.L. (2015). Identification of Malignant Tumors in the Liver. In: Dip, F., Ishizawa, T., Kokudo, N., Rosenthal, R. (eds) Fluorescence Imaging for Surgeons. Springer, Cham. https://doi.org/10.1007/978-3-319-15678-1_16

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  • DOI: https://doi.org/10.1007/978-3-319-15678-1_16

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-15677-4

  • Online ISBN: 978-3-319-15678-1

  • eBook Packages: MedicineMedicine (R0)

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