Abstract
Currently, magnetic nanoparticles show a great variety of applications in the biomedicine area, where they are used for the diagnostic and treatment of diseases by means of transportation and release of drugs, immobilization and magnetic separation of biological entities or treatment of tumors through hyperthermia therapies. An inevitable problem associated with magnetic nanoparticles is their intrinsically instability through time. Besides, the particles without covering are highly reactive chemically and they oxidize quickly in the air, producing a loss of magnetism and their ability of dispersion. For this reason it is crucial to develop strategies of protection during or after the synthesis, to chemically stabilize the magnetic particles against degradation. Magnetic nanoparticles (Fe3O4) were synthesized via co-precipitation of ferrous (Fe2+) and ferric (Fe3+) ions in alkali solution. The morphology and the structure of the nanoparticles were characterized using aberration-corrected (Cs) scanning transmission electron microscopy (STEM). Comparisons between the theoretical and experimental STEM images were carried out and some insights from the atomic structure of the magnetic nanoparticles are shown. Magnetic nanoparticles were obtained with a homogeneous dispersion and average particle size of 19.5 nm.
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Acknowledgments
The authors acknowledge the Laboratorio Avanzado de Nanoscopia Electrónica “LANE” at the CINVESTAV-Zacatenco. Thanks to CONACyT because of the Becerril-Juárez’s postdoctoral scholarship.
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Piñón-Hernández, J.R., Becerril-Juárez, I.G., Ángeles-Pascual, A., Pérez, R., Esparza, R. (2015). Synthesis and Characterization of Magnetic Nanoparticles for Biomedical Applications. In: Pérez Campos, R., Contreras Cuevas, A., Esparza Muñoz, R. (eds) Materials Characterization. Springer, Cham. https://doi.org/10.1007/978-3-319-15204-2_17
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DOI: https://doi.org/10.1007/978-3-319-15204-2_17
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-15203-5
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