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Inherited Bleeding Disorders in Pregnancy: von Willebrand Disease, Factor XI Deficiency, and Hemophilia A and B Carriers

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Disorders of Thrombosis and Hemostasis in Pregnancy

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Abstract

Obstetric management of women with von Willebrand Disease (VWD) and FXI deficiency, and carriers of hemophilia A and B, requires a multi-disciplinary team approach with obstetricians, midwives, hematologists, anesthetists, and neonatologists. This chapter discusses these disorders with particular emphasis on their management during pregnancy, delivery and postpartum. Diagnostic (carrier) testing before becoming pregnant in order to allow appropriate preconception counselling and timely provision of prenatal diagnosis, especially in those who could potentially carry a severely affected baby, are also addressed.

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Authors and Affiliations

  1. Department of Haemophilia, University of London, London, UK

    Christine A. Lee MBChB,MA,MD,DSc,FRCP,FRCPath

  2. Department of Obstetrics and Gynaecology, Royal Free Hospital, Royal Free London NHS Foundation Trust, Hampstead, London, NW3 2QG, UK

    Rezan A. Kadir MB ChB, MRCOG FRCS(Ed), MD

Authors
  1. Christine A. Lee MBChB,MA,MD,DSc,FRCP,FRCPath
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  2. Rezan A. Kadir MB ChB, MRCOG FRCS(Ed), MD
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Correspondence to Rezan A. Kadir MB ChB, MRCOG FRCS(Ed), MD .

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Editors and Affiliations

  1. Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom

    Hannah Cohen

  2. Institute for Women's Health, University College London Hospitals NHS Foundation Trust, London, United Kingdom

    Patrick O'Brien

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Lee, C.A., Kadir, R.A. (2015). Inherited Bleeding Disorders in Pregnancy: von Willebrand Disease, Factor XI Deficiency, and Hemophilia A and B Carriers. In: Cohen, H., O'Brien, P. (eds) Disorders of Thrombosis and Hemostasis in Pregnancy. Springer, Cham. https://doi.org/10.1007/978-3-319-15120-5_11

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  • DOI: https://doi.org/10.1007/978-3-319-15120-5_11

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