Abstract
Laparoscopic cholecystectomy is one of the most commonly performed surgical procedures in the United States. Widespread variability in biliary anatomy can make this procedure quite challenging. These anatomic variations result from the complex nature of biliary system development. This chapter focuses on biliary system embryology, anatomy of the liver, gallbladder and extrahepatic bile ducts, normal physiology of bile production and metabolism, and the natural history of gallstone formation.
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References
El-Gohary Y, Gittes GK. Embryologic development of the liver, biliary tract, and pancreas. In: Blumgart LH, Jarnagin WR, editors. Surgery of the liver and biliary tract. 5th ed. New York: WB Saunders; 2012.
Keplinger KM, Bloomston M. Anatomy and embryology of the biliary tract. Surg Clin North Am. 2014;94:203–17.
Tan C, Moscoso GJ. The developing human biliary system at the porta hepatis level between 29 days and 8 weeks of gestation: a way to understanding biliary atresia. Part 1. Pathol Int. 1994;44:587–99. doi:10.1111/j.1440-1827.1994.tb01719.x.
Nagral S. Anatomy relevant to cholecystectomy. J Minim Access Surg. 2005;1(2):53–8. doi:10.4103/0972-9941.16527.
Clemente CD. Gray’s anatomy. Philadelphia: Lea & Febiger; 1985.
Turner MA, Fulcher AS. The cystic duct: normal anatomy and disease processes. Radiographics. 2001;21:3–22.
Cai JS, Chen JH. The mechanism of enterohepatic circulation in the formation of gallstone disease. J Membr Biol. 2014;247(11):1067–82.
Trotman BW, Soloway RD. Pigment gallstone disease: summary of the National Institutes of Health–international workshop. Hepatology. 1982;2(6):879–84.
Acalovschi M. Gallstones in patients with liver cirrhosis: incidence, etiology, clinical and therapeutical aspects. World J Gastroenterol. 2014;20(23):7277–85.
Dray X, Joy F, Reijasse D, et al. Incidence, risk factors, and complications of cholelithiasis in patients with home parenteral nutrition. J Am Coll Surg. 2007;204(1):13–21.
Hussaini SH, Murphy GM, Kennedy C, et al. The role of bile composition and physical chemistry in the pathogenesis of octreotide-associated gallbladder stones. Gastroenterology. 1994;107:1503–13.
Brown AC, Wrenn SP, Suresh N, Meyers WC, Abedin MZ. Gender differences in cholesterol nucleation in native bile: estrogen is a potential contributory factor. J Membr Biol. 2009;232(1–3):35–45.
Cirillo DJ, et al. Effect of estrogen therapy on gallbladder disease. JAMA. 2005;293:330–9.
Maringhini A, Ciambra M, Baccelliere P, et al. Biliary sludge and gallstones in pregnancy: incidence, risk factors, and natural history. Ann Intern Med. 1993;119:116–20.
Everhart JE. Contributions of obesity and weight loss to gallstone disease. Ann Intern Med. 1993;119:1029–35.
Gebhard RL, Prigge WF, Ansel HJ, et al. The role of gallbladder emptying in gallstone formation during diet-induced rapid weight loss. Hepatology. 1996;24:544–8.
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Maloney, C., Huston, J. (2015). Normal Biliary Anatomy and Pathophysiology of Gallstones. In: Eachempati, S., Reed, II, R. (eds) Acute Cholecystitis. Springer, Cham. https://doi.org/10.1007/978-3-319-14824-3_2
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DOI: https://doi.org/10.1007/978-3-319-14824-3_2
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-14823-6
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