Abstract
Clinical differential diagnosis of hypopigmented patches includes pityriasis alba (P. Alba), mycosis fungoides (MF), sarcoidosis, early vitiligo, progressive macular hypomelanosis (PMH), and tinea versicolor (TV). These disorders vary in their pathophysiology from mild inflammation (P. Alba) to autoimmune (vitiligo) to lymphoma (MF), and a granulomatous disorder (sarcoidosis).
The histological findings of sarcoidosis are highly characteristic, well known, and easily recognizable. The organisms in TV may be recognized by standard microscopy due to their abundance in the stratum corneum. The findings in hypopigmented MF are similar to those in patch-stage MF. The histological findings of P. Alba, PMH, and early vitiligo are not diagnostic.
The most commonly submitted differential diagnosis for disorders in this section is early vitiligo versus hypopigmented MF versus hypopigmented sarcoidosis.
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© 2015 Springer International Publishing Switzerland
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Mutasim, D. (2015). Hypopigmented Patches. In: Practical Skin Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-14729-1_29
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DOI: https://doi.org/10.1007/978-3-319-14729-1_29
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