Abstract
While epicardial coronary involvement directly from sarcoidosis is rare, vasculitis is more common, and overall inflammation may create a milieu for the development of coronary disease. More common is the need for tissue diagnosis for the confirmation of a clinical scenario which suggests myocardial involvement by sarcoidosis granulomatous infiltration. While endomyocardial biopsy is the “gold standard” for a diagnosis of myocardial sarcoidosis, it remains a challenging procedure to capture the affected tissue owing to the patchy nature of the disease. Concomitant electrophysiologic or imaging studies can augment the likelihood of gathering affected tissue, but biopsy sensitivity still remains relatively low. As such, invasive study is certainly useful, but routine use is likely less in line with current standard practice.
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Kim, D., Sauer, W.H. (2015). Invasive Procedures and Endomyocardial Biopsy. In: Freeman, A., Weinberger, H. (eds) Cardiac Sarcoidosis. Springer, Cham. https://doi.org/10.1007/978-3-319-14624-9_8
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DOI: https://doi.org/10.1007/978-3-319-14624-9_8
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