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Special Aspects of Familial Mediterranean Fever in Childhood

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Familial Mediterranean Fever

Part of the book series: Rare Diseases of the Immune System ((RDIS,volume 3))

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Abstract

FMF is a disease, which usually manifests in early childhood: in 90 % of cases, first symptoms are present before the 20th year of life and in 75 % before the 10th year of life [1] (Table 3.1). Immediate postnatal manifestations are reported [2]. A late onset of disease, defined as manifestation after the 40th birthday, is rare and only be present in less the 1 % of patients [3]. In the large Turkish registry, the mean age of manifestation was 9.6 years, the mean age of diagnosis 16.4 years [4]. But the general awareness for the diseases as well as the better diagnostical tools improved the early diagnosis dramatically in the last decades [5].

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Authors and Affiliations

  1. Department for Pediatric Pneumology and Immunology, Charité University Medicine Berlin, Berlin, Germany

    Tilmann Kallinich

  2. İstanbul Kanuni Sultan Süleyman Education and Research Hospital Pediatric Rheumatology Unit, Istanbul, Turkey

    Nuray Aktay

  3. Department of Pediatric Rheumatology, Hacettepe University, Ankara, Turkey

    Seza Ozen

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  1. Tilmann Kallinich
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  2. Nuray Aktay
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  3. Seza Ozen
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Correspondence to Tilmann Kallinich .

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Editors and Affiliations

  1. II Paediatric Unit-Rheumatology, G. Gaslini Institute, Genova, Genova, Italy

    Marco Gattorno

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Kallinich, T., Aktay, N., Ozen, S. (2015). Special Aspects of Familial Mediterranean Fever in Childhood. In: Gattorno, M. (eds) Familial Mediterranean Fever. Rare Diseases of the Immune System, vol 3. Springer, Cham. https://doi.org/10.1007/978-3-319-14615-7_3

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  • DOI: https://doi.org/10.1007/978-3-319-14615-7_3

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