Abstract
Heterotopic heart transplantation in rats has been accepted and widely used as a suitable model for transplant immunology investigation, for new cardioplegic solutions testing and also for heart mechanical unloading research. The heterotopic heart transplantation consists in microsurgical implantation of the donor heart into the host organism while the host heart is preserved untouched. Various spots have been routinely used for the heterotopic heart implantation (abdominal, cervical and femoral). In general, all the approaches mentioned above have the advantage of easy graft functionality assessment by palpation. The heterotopic abdominal transplantation model has become the most widely used one over the years. Gradually, many modifications have been adopted to make the microsurgical procedure faster and easier in order to improve the survival rate.
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© 2015 Springer International Publishing Switzerland
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Pokorny, M., Mrazova, I., Maly, J. (2015). Heterotopic Abdominal Heart Transplantation in Rats. In: Girman, P., Kriz, J., Balaz, P. (eds) Rat Experimental Transplantation Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-14559-4_9
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DOI: https://doi.org/10.1007/978-3-319-14559-4_9
Publisher Name: Springer, Cham
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