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What Is the Best Possible Therapy for My Crohn’s Disease? State-of-the-Art Therapy for Newly Diagnosed Crohn’s Disease

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Inflammatory Bowel Disease

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Abstract

Crohn’s disease is an inflammatory disease whereby the immune system attacks the intestines, causing the inflammation and ulceration that results in abdominal pain, diarrhea, fevers, fatigue, and other symptoms. Some Crohn’s patients suffer from fistulas (inflamed tunnels from the intestines to surrounding skin or other organs). It is believed that the white blood cells are primarily responsible for the damage caused by Crohn’s disease; thus, most therapies are aimed at either directly stopping the white blood cells from being produced or preventing them from recruiting other white blood cells and from attacking the bowel. Genetic studies have suggested that this “attack” is an attempt by the body’s immune system to get at the bacteria and other organisms in the gut [1, 2].

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Author information

Authors and Affiliations

  1. Section of Gastroenterology, Hepatology and Nutrition, The University of Chicago Medicine, Chicago, IL, USA

    Dejan Micic & Atsushi Sakuraba

  2. Advanced IBD Fellowship Program, Department of Medicine, IBD Center, The University of Chicago Medicine, Chicago, IL, USA

    Russell D. Cohen M.D., F.A.C.G., A.G.A.F.

  3. Department of Gastroenterology, The University of Chicago Medicine, Chicago, IL, USA

    Russell D. Cohen M.D., F.A.C.G., A.G.A.F.

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  1. Dejan Micic
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  2. Atsushi Sakuraba
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  3. Russell D. Cohen M.D., F.A.C.G., A.G.A.F.
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Correspondence to Russell D. Cohen M.D., F.A.C.G., A.G.A.F. .

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Editors and Affiliations

  1. Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Daniel J. Stein

  2. Chief, Division Gastroenterology and Hepatology Digestive Disease Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Reza Shaker

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Micic, D., Sakuraba, A., Cohen, R.D. (2015). What Is the Best Possible Therapy for My Crohn’s Disease? State-of-the-Art Therapy for Newly Diagnosed Crohn’s Disease. In: Stein, D., Shaker, R. (eds) Inflammatory Bowel Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-14072-8_9

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  • DOI: https://doi.org/10.1007/978-3-319-14072-8_9

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