Abstract
Inflammatory bowel disease will frequently result in a great deal of pain for individual patients. This pain is frequently treated with narcotic or opioid pain medications. While the initial goal is to use these medications over the short term, their use often will become that of chronic dependence. Chronic narcotic use in IBD patients can lead to poor outcomes for patients in several aspects of their life. This chapter outlines several of the detrimental effects that chronic opioid use can have on IBD patients and explores alternative approaches for pain control in IBD patients.
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References
Lichtenstein GR, Feagan BG, Cohen RD, et al. Serious infections and mortality in association with therapies for Crohn’s disease: TREAT registry. Clin Gastroenterol Hepatol. 2006;4:621–30.
Grunkemeier DM, Cassara JE, Dalton CB, et al. The narcotic bowel syndrome: clinical features, pathophysiology, and management. Clin Gastroenterol Hepatol. 2007;5:1126–39. quiz 1121–2.
Cross RK, Wilson KT, Binion DG. Narcotic use in patients with Crohn’s disease. Am J Gastroenterol. 2005;100:2225–9.
Long MD et al. Narcotic use for inflammatory bowel disease and risk factors during hospitalization. Inflamm Bowel Dis. 2012;18(5):869–76.
Lian L, Fazio VW, Hammel J, Shen B. Impact of narcotic use on the requirement for colectomy in inpatients with ulcerative colitis. Dis Colon Rectum. 2010;53(9):1295–300.
Freeman HJ. Is narcotic addition more prevalent in IBD patient? Inflamm Bowel Dis. 2008;14(Suppl 2) S56. A clinician guide to IBD.
Srinath A et al. Pain management in patients with inflammatory bowel disease: insights for the clinician. Ther Adv Gastroenterol. 2012;5(5):339–57.
Feagins LA, Cryer BL. Do non-steroidal anti-inflammatory drugs cause exacerbations of inflammatory bowel disease? Dig Dis Sci. 2010;55:226–32.
Ippolito C, Segnani C, Errede M, et al. An integrated assessment of histopathological changes of the enteric neuromuscular compartment in experimental colitis. J Cell Mol Med. 2015;19(2):485–500.
Choi K, Chen J, Mitra S, et al. Impaired integrity of DNA after recovery from inflammation causes persistent dysfunction of colonic smooth muscle. Gastroenterology. 2011;141:1293–301.
Colombel JF, Rutgeerts P, Reinsch W, et al. Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis. Gastroenterology. 2011;141:1194–201.
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Rage, A., Stein, D.J. (2015). Why Can’t I Continue to Take My Narcotics? The Long-Term Negative Effects of Narcotics. In: Stein, D., Shaker, R. (eds) Inflammatory Bowel Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-14072-8_16
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DOI: https://doi.org/10.1007/978-3-319-14072-8_16
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-14071-1
Online ISBN: 978-3-319-14072-8
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