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Middle Ear Pressure Regulation: Physiology and Pathology

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Tympanic Membrane Retraction Pocket

Abstract

Based on the previous anatomical knowledge, this chapter will explain the adequate link between the function of ME ventilation and the aspects of its disorders in the pathophysiology of tympanic membrane retractions.

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References

  1. Hergils L, Magnuson B. Regulation of negative middle ear pressure without tubal opening. Arch Otolaryngol Head Neck Surg. 1988;114:1442–4.

    Article  CAS  PubMed  Google Scholar 

  2. Sade J, Luntz M. Gas diffusion in the middle ear. Acta Otolaryngol. 1991;111:354–7.

    Article  CAS  PubMed  Google Scholar 

  3. Ars B, Ars-Piret N. Middle ear pressure balance under normal conditions. Specific role of the middle ear structure. Acta Otorhinolaryngol Belg. 1994;48:339–42.

    CAS  PubMed  Google Scholar 

  4. Lim DJ. Normal and pathological mucosa of the middle ear and eustachian tube. Clin Otolaryngol Allied Sci. 1979;4:213–32.

    Article  CAS  PubMed  Google Scholar 

  5. Ars B, Wuyts F, Van de Heyning P, Miled I, Bogers J, Van Marck E. Histomorphometric study of the normal middle ear mucosa. Preliminary results supporting the gas-exchange function in the postero-superior part of the middle ear cleft. Acta Otolaryngol. 1997;117:704–7.

    Article  CAS  PubMed  Google Scholar 

  6. Kanick SC, Doyle WJ, Ghadiali SN, Federspiel WJ. On morphometric measurement of oxygen diffusing capacity in middle ear gas exchange. J Appl Physiol. 2005;98:114–9.

    Article  PubMed  Google Scholar 

  7. Ars B, Ars-Piret N. Morpho-functional partition of the middle ear cleft. Acta Otorhinolaryngol Belg. 1997;51(3):181–4.

    CAS  PubMed  Google Scholar 

  8. Sade J. Middle ear mucosa. Arch Otolaryngol. 1966;84:137–43.

    Article  CAS  PubMed  Google Scholar 

  9. Felding JU, Rasmussen JB, Lildholt T. Gas composition of the normal and the ventilated middle ear cavity. Scand J Clin Lab Invest. 1987;Suppl 186:31–41.

    Article  Google Scholar 

  10. Grontved A, Moller A, Jorgensen L. Studies on gas tension in the normal middle ear. Gas chromatographic analysis and a new sampling technique. Acta Otolaryngol. 1990; 109:271–7.

    Article  CAS  PubMed  Google Scholar 

  11. Hergils L, Magnuson B. Human middle ear gas composition studied by mass spectrometry. Acta Otolaryngol. 1990;110:92–9.

    Article  CAS  PubMed  Google Scholar 

  12. Ostfeld EJ, Silberberg A. Gas composition and pressure in the middle ear: a model for the physiological steady state. Laryngoscope. 1991;101:297–304.

    Article  CAS  PubMed  Google Scholar 

  13. Kania RE, Herman P, Ar A, Tran Ba Huy P. Technical pitfalls in middle ear gas studies: errors introduced by the gas permeability of tubing and additional dead space. Acta Otolaryngol. 2005;125:529–33.

    Article  PubMed  Google Scholar 

  14. Kania R, Portier F, Lecain E, Marcusohn Y, Ar A, Herman P, et al. Experimental model for investigating trans-mucosal gas exchanges in the middle ear of the rat. Acta Otolaryngol. 2004;124:408–10.

    Article  PubMed  Google Scholar 

  15. Kania RE, Herman P, Tran Ba Huy P, Ar A. Role of nitrogen in transmucosal gas exchange rate in the rat middle ear. J Appl Physiol. 2006;101:1281–7.

    Article  PubMed  Google Scholar 

  16. Fink N, Ar A, Sade J, Barnea O. Mathematical analysis of atelectasis formation in middle ears with sealed ventilation tubes. Acta Physiol Scand. 2003;177:493–505.

    Article  CAS  PubMed  Google Scholar 

  17. Cantekin EI, Doyle WJ, Phillips DC, Bluestone CD. Gas absorption in the middle ear. Ann Otol Rhinol Laryngol. 1980;3(2):71–5. Supplement.

    Google Scholar 

  18. Bylander A, Tjernstrom O, Ivarsson A, Andréasson L. Eustachian tube function and its relation to middle ear pressure in children. Auris Nasus Larynx. 1985;12 Suppl 1:S43–5.

    PubMed  Google Scholar 

  19. Ars BM, Dirckx JJ, Decraemer WF, Ars-Piret NM. Faulty aeration of the middle ear: repercussion on the tympanic membrane lamina propria. In: Sadé J, editor. The Eustachian tube, basic aspects. Amsterdam: Kugler and Ghedini Publications; 1991. p. 365–71.

    Google Scholar 

  20. Rich AR. A physiological study of the eustachian tube and its related muscles. Bull Johns Hopkins Hosp. 1920;31:3005–10.

    Google Scholar 

  21. Cantekin EI, Doyle WJ, Reichert TJ, et al. Dilation of the eustachian tube by electrical stimulation of the mandibular nerve. Ann Otol Rhinol Laryngol. 1979;88:40–51.

    Article  CAS  PubMed  Google Scholar 

  22. Honjo I, Okazaki N, Kumazawa T. Experimental study of the eustachian tube function with regard to its related muscles. Acta Otolaryngol (Stockh). 1979;87:84–9.

    Article  CAS  Google Scholar 

  23. Bluestone CD, Bluestone MB, Coulter J. Eustachian tube: structure, function, role in otitis media. Hamilton/Lewiston: BC Decker; 2005. p. 25–50.

    Google Scholar 

  24. Mondain M, Vidal D, Bouhanna S, Uziel A. Monitoring eustachian tube opening: preliminary results in normal subjects. Laryngoscope. 1997;107:1414–9.

    Article  CAS  PubMed  Google Scholar 

  25. Doyle WJ. The mastoid as a functional rate-limiter of middle ear pressure change. Int J Pediatr Otorhinolaryngol. 2007;71(3):393–402.

    Article  PubMed Central  PubMed  Google Scholar 

  26. Gaihede M, Dirckx JJJ, Jacobsen H, Aernouts J, Søvsø M, Tveterås K. Middle ear pressure regulation-complementary active actions of the mastoid and the eustachian tube. Otol Neurotol. 2010;31(4):603–11.

    PubMed  Google Scholar 

  27. Alper CM, Kitsko DJ, Swarts JD, et al. Role of the mastoid in middle ear pressure regulation. Laryngoscope. 2011;121(2):404–8.

    Article  PubMed Central  PubMed  Google Scholar 

  28. Cinamon U, Sadé J. Mastoid and tympanic membrane as pressure buffers: a quantitative study in a middle ear cleft model. Otol Neurotol. 2003;24(6):839–42.

    Article  PubMed  Google Scholar 

  29. Ars B, Dirckx J, Ars-Piret N, Buytaert J. Insights in the physiology of the human mastoid: message to the surgeon int. J Int Adv Otol. 2012;8(2):296–310.

    Google Scholar 

  30. Sadé J, Fuchs C, Luntz M. Shrapnell membrane and mastoid pneumatization. Arch Otolaryngol Head Neck Surg. 1997;123(6):584–8.

    Article  PubMed  Google Scholar 

  31. Neuman TS, Thoom SR. Physiology and medicine of hyperbaric oxygen therapy. Philadelphia: Elsevier; 2008.

    Google Scholar 

  32. Sadé J. On the function of the pars flaccida: retraction of the pars flaccida and buffering of negative middle ear pressure. Acta Otolaryngol. 1997;117(2):289–92.

    Article  PubMed  Google Scholar 

  33. Sadé J. The buffering effect of middle ear negative pressure by retraction of the pars tensa. Am J Otol. 2000;21(1):20–3.

    Article  PubMed  Google Scholar 

  34. Doyle, 2000 – in Rosowski Eiber A, editor. Middle ear mechanics in research and otology – Proceedings of the 4th international symposium. Singapore: World Scientific Publishing Co. Pte. Ltd.; 2007. p. 314–21.

    Google Scholar 

  35. Pau HW, Sievert U, Just T, Sade J. Pressure changes in the human middle ear without opening the eustachian tube. Acta Otolaryngol. 2009;129:1182–6.

    Article  PubMed  Google Scholar 

  36. Sadé J, Ar A. Middle ear and auditory tube: middle ear clearance, gas exchange, and pressure regulation. Otolaryngol Head Neck Surg. 1997;116:499–524.

    Article  PubMed  Google Scholar 

  37. Matanda R, Van de Heyning P, Bogers J, Ars B. Behaviour of middle ear cleft mucosa during inflammation: histomorphometric study. Acta Otolaryngol. 2006;126:905–9.

    Article  PubMed  Google Scholar 

  38. Klagsbrun M, Soker S. VEGF/VPF: the angiogenesis factor found? Curr Biol. 1993;3:699–702.

    Article  CAS  PubMed  Google Scholar 

  39. Ar A, Herman P, Lecain E, Wassef M, Huy PT, Kania RE. Middle ear gas loss in inflammatory conditions: the role of mucosa thickness and blood flow. Respir Physiol Neurobiol. 2007;155:167–76.

    Article  PubMed  Google Scholar 

  40. Li JP, Kania R, Lecain E, Ar A, Sauvaget E, Tran Ba Huy P, et al. In vivo demonstration of the absorptive function of the middle ear epithelium. Hear Res. 2005;210:1–8.

    Article  PubMed  Google Scholar 

  41. Portier F, Kania R, Planes C, Hsu WC, Couette S, Tran Ba Huy P, et al. Enhanced sodium absorption in middle ear epithelial cells cultured at air-liquid interface. Acta Otolaryngol. 2005;125:16–22.

    Article  CAS  PubMed  Google Scholar 

  42. Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. Eustachian tube endoscopy in patients with chronic ear disease. Laryngoscope. 2000;110(11):1884–9.

    Article  CAS  PubMed  Google Scholar 

  43. Magnan J, Chays A, Cohen JP. Endoscopie de la trompe auditive in Martin C. Magnan J, Bebear JP La trompe auditive (trompe d’Eustache) Arnette Blackwell Editors, Paris 1996. p. 187–201.

    Google Scholar 

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Mansour, S., Magnan, J., Haidar, H., Nicolas, K. (2015). Middle Ear Pressure Regulation: Physiology and Pathology. In: Tympanic Membrane Retraction Pocket. Springer, Cham. https://doi.org/10.1007/978-3-319-13996-8_3

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  • DOI: https://doi.org/10.1007/978-3-319-13996-8_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-13995-1

  • Online ISBN: 978-3-319-13996-8

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