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Babesiosis

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Abstract

Babesiosis is a tick-borne disease caused by protozoa of the genus Babesia. Several species of Babesia have been associated with disease in domestic animals, including Babesia bovis and B. bigemina in cattle, B. caballi in horses, and B. canis, B. vogeli, and B. rossi in dogs. Some species (e.g., B. divergens, B. microti, B. venatorum, and B. duncani) may also infect and cause diseases in humans. The infectivity and pathogenicity of each Babesia species may vary widely. For instance, B. vogeli is less pathogenic than other species that affect dogs, such as B. canis and B. rossi. The diagnosis of babesiosis relies on suggestive clinical signs (e.g., fever, lethargy, and jaundice) and laboratory abnormalities (e.g., anemia and thrombocytopenia) and should be ideally confirmed by cytology or molecular biology techniques. The treatment of animal babesiosis is usually carried out with drugs like imidocarb dipropionate and diminazene diaceturate, whereas for humans, different drug combinations may be used. While vaccines have been licensed for preventing babesiosis in some animal species (e.g., cattle and dogs), the control and prevention of the disease is primarily based on tick control.

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Notes

  1. 1.

    An interesting review of the first discoveries on Babesia was published (Köhler and Köhler 2003) (C.B. Marcondes, personal communication).

References

  • Alecrim I, Pinto B, Avila T et al (1983) Registro do primeiro caso de infecção humana por Babesia spp. no Brasil. Rev Pat Trop 12:11–29

    Google Scholar 

  • Babeș V (1888) Sur l’hémoglobinurie bactérienne du boeuf. CR Acad Sci Paris 107:692–694

    Google Scholar 

  • Babeș V (1889) Die Aetiologie der seuchenhaften Hämoglobinurie des Rindes. Virchows Arch 115(Folge 11, Band 5):81–108

    Google Scholar 

  • Baneth G, Florin-Christensen M, Cardoso L et al (2015) Reclassification of Theileria annae as Babesia vulpes sp. nov. Parasit Vectors 8:207

    Google Scholar 

  • Bloch EM, Herwaldt BL, Leiby DA et al (2012) The third described case of transfusion-transmitted Babesia duncani. Transfusion 52:1517–1522

    Article  PubMed  Google Scholar 

  • Bosman AM, Oosthuizen MC, Venter EH et al (2013) Babesia lengau associated with cerebral and haemolytic babesiosis in two domestic cats. Parasit Vectors 6:128

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Conrad PA, Kjemtrup AM, Carreno RA et al (2006) Description of Babesia duncani n. sp. (Apicomplexa: Babesiidae) from humans and its differentiation from other piroplasms. Int J Parasitol 36:779–789

    Article  PubMed  Google Scholar 

  • Dantas-Torres F, Capelli G, Giannelli A et al (2013) Efficacy of an imidacloprid/flumethrin collar against fleas, ticks and tick-borne pathogens in dogs. Parasit Vectors 6:245

    Article  PubMed  PubMed Central  Google Scholar 

  • França RT, Da Silva AS, Loretti AP et al (2014) Canine rangeliosis due to Rangelia vitalii: from first report in Brazil in 1910 to current day—a review. Ticks Tick Borne Dis 5:466–474

    Article  PubMed  Google Scholar 

  • Froberg MK, Dannen D, Bakken JS (2004) Babesiosis and HIV. Lancet 363:704

    Article  PubMed  Google Scholar 

  • Hildebrandt A, Gray JS, Hunfeld KP (2013) Human babesiosis in Europe: what clinicians need to know. Infection 41:1057–1072

    Article  CAS  PubMed  Google Scholar 

  • Hunfeld KP, Hildebrandt A, Gray JS (2008) Babesiosis: recent insights into an ancient disease. Int J Parasitol 38:1219–1237

    Article  CAS  PubMed  Google Scholar 

  • Jacobson LS (2006) The South African form of severe and complicated canine babesiosis: clinical advances 1994–2004. Vet Parasitol 138:126–139

    Article  PubMed  Google Scholar 

  • Kim CM, Blanco LB, Alhassan A et al (2008) Development of a rapid immunochromatographic test for simultaneous serodiagnosis of bovine babesioses caused by Babesia bovis and Babesia bigemina. Am J Trop Med Hyg 78:117–121

    CAS  PubMed  Google Scholar 

  • Köhler M, Köhler W (2003) Zentralblatt für Bakteriologie—100 years ago Victor Babeș and enzootic haemoglobinuria of cattle. Int J Med Microbiol 293:233–239

    Article  PubMed  Google Scholar 

  • Lobo CA, Cursino-Santos JR, Alhassan A et al (2013) Babesia: an emerging infectious threat in transfusion medicine. PLoS Pathog 9, e1003387

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mehlhorn H, Schein E (1984) The piroplasms: life cycle and sexual stages. Adv Parasitol 23:37–103

    Article  CAS  PubMed  Google Scholar 

  • Mudaliar SV, Achary GR, Alwar VS (1950) On a species of Babesia in an Indian wild cat (Felis catus). Indian Vet J 26:392–395

    CAS  PubMed  Google Scholar 

  • Ríos L, Alvarez G, Blair S (2003) Serological and parasitological study and report of the first case of human babesiosis in Colombia. Rev Soc Bras Med Trop 36:493–498

    Article  PubMed  Google Scholar 

  • Ruiz de Gopegui R, Peñalba B et al (2007) Clinico-pathological findings and coagulation disorders in 45 cases of canine babesiosis in Spain. Vet J 174:129–132

    Article  PubMed  Google Scholar 

  • Schnittger L, Rodriguez AE, Florin-Christensen M et al (2012) Babesia: a world emerging. Infect Genet Evol 12:1788–1809

    Article  PubMed  Google Scholar 

  • Schoeman JP (2009) Canine babesiosis. Onderstepoort J Vet Res 76:59–66

    Article  CAS  PubMed  Google Scholar 

  • Setty S, Khalil Z, Schori P et al (2003) Babesiosis. Two atypical cases from Minnesota and a review. Am J Clin Pathol 120:554–559

    Article  PubMed  Google Scholar 

  • Silva AS, França RT, Costa MM et al (2011) Experimental infection with Rangelia vitalii in dogs: acute phase, parasitemia, biological cycle, clinical-pathological aspects and treatment. Exp Parasitol 128:347–352

    Article  PubMed  Google Scholar 

  • Smith T, Kilbourne FL (1893) Investigation into the nature, causation and prevention of Texas fever or southern cattle fever. US Dept. Agric., Bur. Anim. Ind., 8th and 9th Ann. Repts, pp 177–301

    Google Scholar 

  • Soares JF, Dall’Agnol B, Costa FB (2014) Natural infection of the wild canid, Cerdocyon thous, with the piroplasmid Rangelia vitalii in Brazil. Vet Parasitol 202:156–163

    Article  CAS  PubMed  Google Scholar 

  • Solano-Gallego L, Baneth G (2011) Babesiosis in dogs and cats—expanding parasitological and clinical spectra. Vet Parasitol 181:48–60

    Article  PubMed  Google Scholar 

  • Sondgeroth KS, McElwain TF, Allen AJ et al (2013) Loss of neurovirulence is associated with reduction of cerebral capillary sequestration during acute Babesia bovis infection. Parasit Vectors 6:181

    Article  PubMed  PubMed Central  Google Scholar 

  • Starcovici C (1893) Bemerkungen über den durch Babes entdeckten Blutparasiten und die durch denselben hervorgebrachten Krankheiten, die seuchenhafte Hämoglobinurie des Rindes (Babes), das Texasfieber (Th. Smith) und der Carceag der Schafe (Babes). Zbl Bakt I Abt 14:1–8

    Google Scholar 

  • Uilenberg G (2006) Babesia—a historical overview. Vet Parasitol 138:3–10

    Article  PubMed  Google Scholar 

  • Vannier E, Gewurz BE, Krause PJ (2008) Human babesiosis. Infect Dis Clin North Am 22:469–488

    Article  PubMed  PubMed Central  Google Scholar 

  • Vial HJ, Gorenflot A (2006) Chemotherapy against babesiosis. Vet Parasitol 138:147–160

    Article  CAS  PubMed  Google Scholar 

  • Wong SS, Poon RW, Hui JJ et al (2012) Detection of Babesia hongkongensis sp. nov. in a free-roaming Felis catus cat in Hong Kong. J Clin Microbiol 50:2799–803

    Article  PubMed  PubMed Central  Google Scholar 

  • Yabsley MJ, Shock BC (2012) Natural history of zoonotic Babesia: role of wildlife reservoirs. Int J Parasitol Parasites Wildl 2:18–31

    Article  PubMed  PubMed Central  Google Scholar 

  • Zahler M, Rinder H, Schein E et al (2000) Detection of a new pathogenic Babesia microti-like species in dogs. Vet Parasitol 89:241–248

    Google Scholar 

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Correspondence to Filipe Dantas-Torres .

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Dantas-Torres, F., Alves, L.C., Uilenberg, G. (2017). Babesiosis. In: Marcondes, C. (eds) Arthropod Borne Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-13884-8_21

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  • DOI: https://doi.org/10.1007/978-3-319-13884-8_21

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