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Infection and Biofilms

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Prosthetic Surgery in Urology

Abstract

Prosthetics in general are susceptible to bacterial infection often with disastrous consequences, especially if not recognized and managed promptly. Consequently a good working knowledge of the underlying concepts of infections and biofilms is essential for clinicians involved in this area of urological surgery.

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References

  1. Mack WN, Mack JP, Ackerson AO. Microbial film development in a trickling filter. Microb Ecol. 1975;2(3):215–26.

    Article  CAS  PubMed  Google Scholar 

  2. Geesey GG, Richardson WT, Yeomans HG, Irvin RT, Costerton JW. Microscopic examination of natural sessile bacterial populations from an alpine stream. Can J Microbiol. 1977;23(12):1733–6.

    Article  CAS  PubMed  Google Scholar 

  3. Heukelekian H, Heller A. Relation between food concentration and surface for bacterial growth. J Bacteriol. 1940;40(4):547–58.

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Zobell CE, Grant CW. Bacterial utilization of low concentrations of organic matter. J Bacteriol. 1943;45(6):555–64.

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Donlan RM. Biofilms: microbial life on surfaces. Emerg Infect Dis. 2002;8(9):881–90.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Stewart PS, Franklin MJ. Physiological heterogeneity in biofilms. Nat Rev Microbiol. 2008;6(3):199–210.

    Article  CAS  PubMed  Google Scholar 

  7. Griffith F. The significance of pneumococcal types. J Hyg. 1928;27(2):113–59.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Babic A, Lindner AB, Vulic M, Stewart EJ, Radman M. Direct visualization of horizontal gene transfer. Science. 2008;319(5869):1533–6.

    Article  CAS  PubMed  Google Scholar 

  9. Whitchurch CB, Tolker-Nielsen T, Ragas PC, Mattick JS. Extracellular DNA required for bacterial biofilm formation. Science. 2002;295(5559):1487.

    Article  CAS  PubMed  Google Scholar 

  10. Li YH, Lau PC, Lee JH, Ellen RP, Cvitkovitch DG. Natural genetic transformation of Streptococcus mutans growing in biofilms. J Bacteriol. 2001;183(3):897–908.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Costerton JW, Stewart PS, Greenberg EP. Bacterial biofilms: a common cause of persistent infections. Science. 1999;284(5418):1318–22.

    Article  CAS  PubMed  Google Scholar 

  12. Lewis K. Persister cells: molecular mechanisms related to antibiotic tolerance. Handb Exp Pharmacol. 2012;211:121–33.

    Article  CAS  PubMed  Google Scholar 

  13. Characklis WG, McFeters GA, Marshall KC. Physiological ecology in biofilm systems. In: Biofilms. New York: Wiley; 1990. p. 341–94.

    Google Scholar 

  14. Stickler DJ. Bacterial biofilms in patients with indwelling urinary catheters. Nat Clin Pract Urol. 2008;5:598–608. doi:10.1038/ncpuro1231.

    Article  CAS  PubMed  Google Scholar 

  15. Garibaldi RA, Burke JP, Britt MR, Miller MA, Smith CB. Meatal colonization and catheter-associated bacteriuria. N Engl J Med. 1980;303(6):316–8.

    Article  CAS  PubMed  Google Scholar 

  16. Garibaldi RA, Mooney BR, Epstein BJ, Britt MR. An evaluation of daily bacteriologic monitoring to identify preventable episodes of catheter-associated urinary tract infection. Infect Control IC. 1982;3(6):466–70.

    Article  CAS  PubMed  Google Scholar 

  17. Warren JW, Tenney JH, Hoopes JM, Muncie HL, Anthony WC. A prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters. J Infect Dis. 1982;146(6):719–23.

    Article  CAS  PubMed  Google Scholar 

  18. Stamm WE. Urinary tract infections. In: Bennett JV, Brachman PS, editors. Hospital infection. 4th ed. Philadelphia: Lippincott-Raven; 1998. p. 477–85.

    Google Scholar 

  19. Platt R, Polk BF, Murdock B, Rosner B. Mortality associated with nosocomial urinary-tract infection. N Engl J Med. 1982;307(11):637–42.

    Article  CAS  PubMed  Google Scholar 

  20. Saint S. Clinical and economic consequences of nosocomial catheter-related bacteriuria. Am J Infect Control. 2000;28(1):68–75.

    Article  CAS  PubMed  Google Scholar 

  21. Data and statistics of healthcare associated infections. 2014 [01/08/2014]. Available from: http://www.cdc.gov/HAI/surveillance/index.html.

  22. 2016 NHSN Patient Safety Component Manual. [02/04/2016]. Available from: http://www.cdc.gov/nhsn/.

  23. Tambyah PA, Halvorson KT, Maki DG. A prospective study of pathogenesis of catheter-associated urinary tract infections. Mayo Clin Proc. 1999;74(2):131–6.

    Article  CAS  PubMed  Google Scholar 

  24. Chenoweth CE, Gould CV, Saint S. Diagnosis, management, and prevention of catheter-associated urinary tract infections. Infect Dis Clin North Am. 2014;28(1):105–19.

    Article  PubMed  Google Scholar 

  25. Donlan RM, Costerton JW. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev. 2002;15(2):167–93.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Sabbuba N, Hughes G, Stickler DJ. The migration of Proteus mirabilis and other urinary tract pathogens over Foley catheters. BJU Int. 2002;89(1):55–60.

    Article  CAS  PubMed  Google Scholar 

  27. Warren JW. Catheter-associated urinary tract infections. Int J Antimicrob Agents. 2001;17(4):299–303.

    Article  CAS  PubMed  Google Scholar 

  28. Sievert DM, Ricks P, Edwards JR, Schneider A, Patel J, Srinivasan A, et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010. Infect Control Hosp Epidemiol Off J Soc Hosp Epidemiol Am. 2013;34(1):1–14.

    Article  Google Scholar 

  29. Dalhoff A. Global fluoroquinolone resistance epidemiology and implications for clinical use. Interdiscip Perspect Infect Dis. 2012;2012:976273.

    PubMed  PubMed Central  Google Scholar 

  30. Grabe M, Bartoletti R, Bjerklund Johansen TE, Cai T, Cek M, Koves B, Naber KG, Pickard RS, Tenke P, Wagenlehner F, Wullt B. Guidelines on urological infections. 2015. 12 Apr 2015. Available from: http://uroweb.org/guideline/urological-infections/.

  31. Hooton TM, Bradley SF, Cardenas DD, Colgan R, Geerlings SE, Rice JC, et al. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis Off Publ Infect Dis Soc Am. 2010;50(5):625–63.

    Article  Google Scholar 

  32. Naber KG, et al. Urogenital infections, in International Consultations on Urological Diseases. 2010. 12 Apr 2015. Available from: http://www.icud.info/PDFs/ICUD%20Urogenital%20Infections.pdf.

  33. Raz R, Schiller D, Nicolle LE. Chronic indwelling catheter replacement before antimicrobial therapy for symptomatic urinary tract infection. J Urol. 2000;164(4):1254–8.

    Article  CAS  PubMed  Google Scholar 

  34. Kehinde EO, Rotimi VO, Al-Hunayan A, Abdul-Halim H, Boland F, Al-Awadi KA. Bacteriology of urinary tract infection associated with indwelling J ureteral stents. J Endourol Endourol Soc. 2004;18(9):891–6.

    Article  Google Scholar 

  35. Reid G, Denstedt JD, Kang YS, Lam D, Nause C. Microbial adhesion and biofilm formation on ureteral stents in vitro and in vivo. J Urol. 1992;148(5):1592–4.

    CAS  PubMed  Google Scholar 

  36. Kehinde EO, Rotimi VO, Al-Awadi KA, Abdul-Halim H, Boland F, Al-Hunayan A, et al. Factors predisposing to urinary tract infection after J ureteral stent insertion. J Urol. 2002;167(3):1334–7.

    Article  PubMed  Google Scholar 

  37. Wolf JS, Bennett C, Dmochowski RR, Hollenbeck BK, Pearle MS, Schaeffer AJ. Best practice policy statement on urological surgery antimicrobial prophylaxis. 2008. 10 Apr 2015. Available from: https://www.auanet.org/education/guidelines/antimicrobial-prophylaxis.cfm.

    Google Scholar 

  38. Qiang W, Jianchen W, MacDonald R, Monga M, Wilt TJ. Antibiotic prophylaxis for transurethral prostatic resection in men with preoperative urine containing less than 100,000 bacteria per ml: a systematic review. J Urol. 2005;173(4):1175–81.

    Article  PubMed  Google Scholar 

  39. MacDermott JP, Ewing RE, Somerville JF, Gray BK. Cephradine prophylaxis in transurethral procedures for carcinoma of the bladder. Br J Urol. 1988;62(2):136–9.

    Article  CAS  PubMed  Google Scholar 

  40. Wagenlehner FM, Wagenlehner C, Schinzel S, Naber KG, Working Group “Urological Infections” of German Society of Urology. Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate. Eur Urol. 2005;47(4):549–56.

    Article  CAS  PubMed  Google Scholar 

  41. Henry GD, Wilson SK, Delk 2nd JR, Carson CC, Silverstein A, Cleves MA, et al. Penile prosthesis cultures during revision surgery: a multicenter study. J Urol. 2004;172(1):153–6.

    Article  PubMed  Google Scholar 

  42. McCann MT, Gilmore BF, Gorman SP. Staphylococcus epidermidis device-related infections: pathogenesis and clinical management. J Pharm Pharmacol. 2008;60(12):1551–71.

    Article  CAS  PubMed  Google Scholar 

  43. Tanner J, Woodings D, Moncaster K. Preoperative hair removal to reduce surgical site infection. Cochrane Database Syst Rev. 2006;(2):CD004122.

    Google Scholar 

  44. Yeung LL, Grewal S, Bullock A, Lai HH, Brandes SB. A comparison of chlorhexidine-alcohol versus povidone-iodine for eliminating skin flora before genitourinary prosthetic surgery: a randomized controlled trial. J Urol. 2013;189(1):136–40.

    Article  PubMed  Google Scholar 

  45. Mansouri MD, Boone TB, Darouiche RO. Comparative assessment of antimicrobial activities of antibiotic-treated penile prostheses. Eur Urol. 2009;56(6):1039–45.

    Article  PubMed  Google Scholar 

  46. Wilson SK, Costerton JW. Biofilm and penile prosthesis infections in the era of coated implants: a review. J Sex Med. 2012;9(1):44–53.

    Article  PubMed  Google Scholar 

  47. Mandava SH, Serefoglu EC, Freier MT, Wilson SK, Hellstrom WJ. Infection retardant coated inflatable penile prostheses decrease the incidence of infection: a systematic review and meta-analysis. J Urol. 2012;188(5):1855–60.

    Article  PubMed  Google Scholar 

  48. Eid JF, Wilson SK, Cleves M, Salem EA. Coated implants and “no touch” surgical technique decreases risk of infection in inflatable penile prosthesis implantation to 0.46%. Urology. 2012;79(6):1310–5.

    Article  PubMed  Google Scholar 

  49. de Cogain MR, Elliott DS. The impact of an antibiotic coating on the artificial urinary sphincter infection rate. J Urol. 2013;190(1):113–7.

    Article  PubMed  Google Scholar 

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Correspondence to Arie S. Parnham MBChB, FRCS (Urol) .

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Parnham, A.S., Sangar, V.K. (2016). Infection and Biofilms. In: Muneer, A., Pearce, I., Ralph, D. (eds) Prosthetic Surgery in Urology. Springer, Cham. https://doi.org/10.1007/978-3-319-13859-6_3

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  • DOI: https://doi.org/10.1007/978-3-319-13859-6_3

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