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Glucagonoma

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Surgical Endocrinopathies

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Abstract

Glucagonoma is a rare tumor of pancreatic islet cells. The hyperglucagonemia causes a paraneoplastic syndrome, of which the most well-known feature is a migratory rash, called necrolytic migratory erythema. Other findings include diabetes, weight loss, anemia, thromboembolic disease, and depression. Diagnosis is often delayed, and many patients present with advanced or metastatic disease. Successful treatment leads to rapid resolution of symptoms, and surgery should be considered even in patients who cannot be rendered disease free, in order to achieve symptom reduction.

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Authors and Affiliations

  1. Rhode Island Hospital, Warren Alpert School of Medicine, Brown University, 2 Dudley St., 02905, Providence, RI, USA

    Assoc. Prof. Peter J. Mazzaglia MD FACS

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  1. Assoc. Prof. Peter J. Mazzaglia MD FACS
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Correspondence to Peter J. Mazzaglia MD FACS .

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Editors and Affiliations

  1. Divisions of General Surgery and Surgical Oncology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada

    Janice L. Pasieka

  2. Department of Surgery, Columbia University Medical Center, New York, New York, USA

    James A. Lee

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Mazzaglia, P. (2015). Glucagonoma. In: Pasieka, J., Lee, J. (eds) Surgical Endocrinopathies. Springer, Cham. https://doi.org/10.1007/978-3-319-13662-2_52

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  • DOI: https://doi.org/10.1007/978-3-319-13662-2_52

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-13661-5

  • Online ISBN: 978-3-319-13662-2

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