Skip to main content

Glucose Oxidase Biosensor Modeling by Machine Learning Methods

  • Conference paper
Nature-Inspired Computation and Machine Learning (MICAI 2014)

Abstract

Biosensors are small analytical devices incorporating a biological element for signal detection. The main function of a biosensor is to generate an electrical signal which is proportional to a specific analyte i.e. to translate a biological signal into an electrical reading. Nowadays its technological attractiveness resides in its fast performance, and its highly sensitivity and continuous measuring capabilities; however, its understanding is still under research. This paper focuses to contribute to the state of the art of this growing field of biotechnology specially on Glucose Oxidase Biosensors (GOB) modeling through statistical learning methods from a regression perspective. It models the amperometric response of a GOB with dependent variables under different conditions such as temperature, benzoquinone, PH and glucose, by means of well known machine learning algorithms. Support Vector Machines(SVM), Artificial Neural Networks (ANN) and Partial least squares (PLS) are the algorithms selected to do the regression task.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Antoniadis, A., Bigot, J., Sapatinas, T.: Wavelet estimators in nonparametric regression: A comparative simulation study. Journal of Statistical Software 6(6), 1–83 (2001), http://www.jstatsoft.org/v06/i06

    Google Scholar 

  2. Blaedel, W.J., Kissel, T.R., Boguslaski, R.C.: Kinetic behavior of enzymes immobilized in artificial membranes. Analytical Chemistry 44(12), 2030–2037 (1972), http://pubs.acs.org/doi/abs/10.1021/ac60320a021 pMID: 4657296

    Article  Google Scholar 

  3. Borgmann, S., Schulte, A., Neugebauer, S., Schuhmann, W.: Amperometric biosensors. In: Alkire, R., Kolb, D., Lipkowski, J. (eds.) Bioelectrochemistry: Fundamentals, Applications and Recent Developments. Wiley-VCH (2011)

    Google Scholar 

  4. Malhotra, B., Turner, A.: Advances in Biosensors: Perspectives in Biosensors. Advances in Biosensors, Elsevier Science (2003), http://books.google.com.mx/books?id=d8i_2uJ4N-oC

  5. Prodromidis, M., Karayannis, M.: Enzyme based amperometric biosensors for food analysis. Electroanalysis 14(4), 241–261 (2002), http://dx.doi.org/10.1002/1521-410920020214:4241:AID-ELAN2413.0.CO;2-P

    Article  Google Scholar 

  6. Rangelova, V., Tsankova, D., Dimcheva, N.: Soft computing techniques in modelling the influence of ph and temperature on dopamine biosensor. In: Somerset, V. (ed.) Intelligent and Biosensors. INTECH (2010)

    Google Scholar 

  7. Sadana, A.: Biosensors: Kinetics of Binding and Dissociation Using Fractals: Kinetics of Binding and Dissociation Using Fractals. Elsevier Science (2003), http://books.google.com.mx/books?id=vlnYu7XA_mQC

  8. Scheller, F., Schubert, F.: Biosensors. Techniques and Instrumentation in Analytical Chemistry. Elsevier Science (1991), http://books.google.com.mx/books?id=TF7AW4kSY1gC

  9. Thévenot, D., Toth, K., Durst, R., Wilson, G.: Electrochemical biosensors: recommended definitions and classification. Biosensors and Bioelectronics 16(1-2), 121–131 (2001)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this paper

Cite this paper

Rentería-Gutiérrez, L., González-Navarro, F.F., Stilianova-Stoytcheva, M., Belanche-Muñoz, L.A., Flores-Ríos, B.L., Ibarra-Esquer, J.E. (2014). Glucose Oxidase Biosensor Modeling by Machine Learning Methods. In: Gelbukh, A., Espinoza, F.C., Galicia-Haro, S.N. (eds) Nature-Inspired Computation and Machine Learning. MICAI 2014. Lecture Notes in Computer Science(), vol 8857. Springer, Cham. https://doi.org/10.1007/978-3-319-13650-9_40

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-13650-9_40

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-13649-3

  • Online ISBN: 978-3-319-13650-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics