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Advanced Nanomaterials: Promises for Improved Dental Tissue Regeneration

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Book cover Nanotechnology in Endodontics

Abstract

Nanotechnology is emerging as an interdisciplinary field that is undergoing rapid development and has become a powerful tool for various biomedical applications such as tissue regeneration, drug delivery, biosensors, gene transfection, and imaging. Nanomaterial-based design is able to mimic some of the mechanical and structural properties of native tissue and can promote biointegration. Ceramic-, metal-, and carbon-based nanoparticles possess unique physical, chemical, and biological characteristics due to the high surface-to-volume ratio. A range of synthetic nanoparticles such as hydroxyapatite, bioglass, titanium, zirconia, and silver nanoparticles are proposed for dental restoration due to their unique bioactive characteristic. This review focuses on the most recent development in the field of nanomaterials with emphasis on dental tissue engineering that provides an inspiration for the development of such advanced biomaterials. In particular, we discuss synthesis and fabrication of bioactive nanomaterials, examine their current limitations, and conclude with future directions in designing more advanced nanomaterials.

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Authors and Affiliations

  1. Biomedical Engineering, Texas A&M University, College Station, TX, USA

    Janet R. Xavier BTech & Prachi Desai BTech

  2. Biomedical Sciences, Texas A&M University Baylor College of Dentistry, Dallas, TX, USA

    Venu Gopal Varanasi PhD

  3. Periodontics, Texas A&M University Baylor College of Dentistry, Dallas, TX, USA

    Ibtisam Al-Hashimi BDS, MS, PhD

  4. Department of Biomedical Engineering, Department of Materials Science and Engineering, Texas A&M University, 3120 TAMU, ETB 5024, College Station, TX, 77843, USA

    Akhilesh K. Gaharwar PhD

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  1. Janet R. Xavier BTech
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  2. Prachi Desai BTech
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  3. Venu Gopal Varanasi PhD
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  4. Ibtisam Al-Hashimi BDS, MS, PhD
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  5. Akhilesh K. Gaharwar PhD
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Correspondence to Akhilesh K. Gaharwar PhD .

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Editors and Affiliations

  1. Department of Clinical Sciences Discipline of Endodontics, University of Toronto Faculty of Dentistry, Toronto, Ontario, Canada

    Anil Kishen

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Xavier, J.R., Desai, P., Varanasi, V.G., Al-Hashimi, I., Gaharwar, A.K. (2015). Advanced Nanomaterials: Promises for Improved Dental Tissue Regeneration. In: Kishen, A. (eds) Nanotechnology in Endodontics. Springer, Cham. https://doi.org/10.1007/978-3-319-13575-5_2

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