Abstract
Proteomics is one of the most powerful tools for studying functional genomics. Although genomics is the most popular tool for bacterial gene studies, proteomics provides novel and distinctive information on gene products (i.e., proteins), including information on translational levels, post-translational modifications, turnover, and cellular localization, that cannot be provided by genomics. Recently, proteomics has been used to perform physiological and metabolic studies on extremophiles. In this chapter, we briefly summarize the basic concept of proteomics, introduce proteomic technologies that are applicable to bacteria and archaea extremophiles, and describe the screening methods for identifying novel proteins in various extremophile sample sets.
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Sung Ho Yun, Chi-Won Choi, Sang-Yeop Lee, Edmond Changkyun Park, and Seung Il Kim declare that they have no conflict of interest.
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Yun, S.H., Choi, CW., Lee, SY., Park, E.C., Kim, S.I. (2016). A Proteomics Approach for the Identification of Novel Proteins in Extremophiles. In: Rampelotto, P. (eds) Biotechnology of Extremophiles:. Grand Challenges in Biology and Biotechnology, vol 1. Springer, Cham. https://doi.org/10.1007/978-3-319-13521-2_10
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DOI: https://doi.org/10.1007/978-3-319-13521-2_10
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