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Treatment of Nonsyndromic Anomalies of Tooth Number

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Craniofacial and Dental Developmental Defects

Abstract

Nonsyndromic tooth agenesis represents a common odontogenic condition that should be managed by a multidisciplinary specialty team. The genetic basis for agenesis of teeth reflects the key transcriptional events involved in mesenchymal-epithelial interactions during tooth formation. Mutations of genes including PAX9, MSX1, AXIN2, and EDA are implicated. Clinicians should be aware of familial history of tooth agenesis. Treatment may involve orthodontists and prosthodontists early in the management of these individuals. In all cases, the establishment of oral health, stable occlusion, and establishment of a conceptual framework for treatment resulting in efficient tooth replacement and aesthetic outcomes should be considered in the mixed dentition phase. Definitive tooth replacement using conventional or implant prostheses should be reserved for individuals with complete facial growth and maturation.

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Authors and Affiliations

  1. Department of Prosthodontics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    Lyndon F. Cooper DDS, PhD

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  1. Lyndon F. Cooper DDS, PhD
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Correspondence to Lyndon F. Cooper DDS, PhD .

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Editors and Affiliations

  1. Department of Pediatric Dentistry, University of North Carolina School of Dentistry, Chapel Hill, North Carolina, USA

    J Timothy Wright

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© 2015 Springer International Publishing Switzerland

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Cooper, L.F. (2015). Treatment of Nonsyndromic Anomalies of Tooth Number. In: Wright, J. (eds) Craniofacial and Dental Developmental Defects. Springer, Cham. https://doi.org/10.1007/978-3-319-13057-6_4

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  • DOI: https://doi.org/10.1007/978-3-319-13057-6_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-13056-9

  • Online ISBN: 978-3-319-13057-6

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