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Panic Disorder and Personality Disorder Comorbidity

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Panic Disorder

Abstract

The present chapter systematically reviews the relationship between panic disorder, with and without co-occurring anxiety or depression, and current personality disorder. Data were collected with an advanced document protocol according to MOOSE (Meta-analysis of Observational Studies in Epidemiology) guidelines for observational studies. A comprehensive, computerized literature search was conducted in Medline, PsycINFO, and LILACS. Cohort, case-control and cross-sectional surveys studies evaluating the comorbidity between DSM panic disorder and personality disorders were included. Overall prevalence, comorbidity rates, and 95 % CI were calculated with a random effects model. From 97 initial selected papers, 24 entered in the review. Among patients with a current DSM-III/R/IV panic disorder, 44.3 % (34.6–54.2 %) had any personality disorder; 6.3 % (3.1–10.4 %) had cluster A; 17.9 % (12.2–24.2 %) cluster B, and 34.9 % (25.6–44.7 %) had cluster C. Among patients with a current panic disorder and co-occurring anxiety or depression, 61.8 % (44.6–77.7 %) had any personality disorder, 7.2 % (4.4–10.5 %) had cluster A; 24.0 % (17.6–30.9 %) cluster B, and 38.6 % (25.7–52.2 %) had cluster C. In conclusion, comorbidity between panic disorder and personality disorders is common. Cluster C was the most frequent personality disorder subtype related to panic disorder. Personality disorders were more prevalent among individuals with panic disorder and co-occurring anxiety or depression.

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Acknowledgements

This chapter was done in part with the support of Generalitat de Catalunya SGR2009/1435 and SGR2014/1411, and Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), G25, Barcelona, Spain.

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Authors and Affiliations

  1. Department of Psychiatry and Psychology, Hospital Clinic, Institut d’Investigació Biomèdica August Pi I Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), G25, Universidad de Barcelona, Barcelona, Spain

    Ricard Navinés & Rocío Martín-Santos

  2. Department of Psychiatry and Psychology, Hospital Clinic, Barcelona, Spain

    Elfi Egmond

  3. Department of Clinical and Health Psychology, Faculty of Psychology, Universidad Autònoma de Barcelona, Cerdanyola del Vallés, Barcelona, Spain

    Elfi Egmond

Authors
  1. Ricard Navinés
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  2. Elfi Egmond
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  3. Rocío Martín-Santos
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Correspondence to Rocío Martín-Santos .

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Editors and Affiliations

  1. Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Antonio Egidio Nardi

  2. Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Rafael Christophe R. Freire

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Navinés, R., Egmond, E., Martín-Santos, R. (2016). Panic Disorder and Personality Disorder Comorbidity. In: Nardi, A., Freire, R. (eds) Panic Disorder. Springer, Cham. https://doi.org/10.1007/978-3-319-12538-1_10

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  • DOI: https://doi.org/10.1007/978-3-319-12538-1_10

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