Skip to main content

A Primary Care Perspective on Prescribing for Women

  • Chapter
  • First Online:
Medicines For Women
  • 1129 Accesses

Abstract

A recent paper indicates that in older patients receiving angiotensin converting enzyme inhibitors or angiotensin receptor blockers, co-trimoxazole is associated with an increased risk of sudden death. This is probably related to trimpethoprim-induced sudden hyperkalemia. Other drugs such as nitrofurantoin should be chosen first line where a woman is taking an ACE or an ARB, or potassium should be monitored, Fralick et al. (BMJ 349:g6196, 2014).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Alexander GC, Sayla MA, Holmes HM, Sachs GA (2006) Prioritizing and stopping prescription medicines. CMAJ 174:1083–1084

    Article  PubMed Central  PubMed  Google Scholar 

  • Andrade SE, Raebel MA, Morse AN, Davis RL, Chan KA, Finkelstein JA, Fortman KK, Mcphillips H, Roblin D, Smith DH, Yood MU, Platt R, Gurwitz JH (2006) Use of prescription medications with a potential for fetal harm among pregnant women. Pharmacoepidemiol Drug Saf 15:546–554

    Article  PubMed  Google Scholar 

  • Arroll B, Macgillivray S, Ogston S, Reid I, Sullivan F, Williams B, Crombie I (2005) Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: a meta-analysis. Ann Fam Med 3:449–456

    Article  PubMed Central  PubMed  Google Scholar 

  • Ashton H (1991) Psychotropic-drug prescribing for women. Br J Psychiatry 158(Suppl 10):30–35

    Google Scholar 

  • Baker GR, Norton PG, Flintoft V, Blais R, Brown A, Cox J, Etchells E, Ghali WA, Hébert P, Majumdar SR, O’beirne M, Palacios-Derflingher L, Reid RJ, Sheps S, Tamblyn R (2004) The Canadian Adverse Events Study: the incidence of adverse events among hospital patients in Canada. CMAJ 170:1678–1686

    Article  PubMed Central  PubMed  Google Scholar 

  • Bednar MM, Harrigan EP, Ruskin JN (2002) Torsades de pointes associated with nonantiarrhythmic drugs and observations on gender and QTc. Am J Cardiol 89:1316–1319

    Article  CAS  PubMed  Google Scholar 

  • Bell RA, Kravitz RL, Wilkes MS (2000) Direct-to-consumer prescription drug advertising, 1989–1998. A content analysis of conditions, targets, inducements, and appeals. J Fam Prac 49:329–335

    CAS  Google Scholar 

  • Benton RE, Sale M, Flockhart DA, Woosley RL (2000) Greater quinidine-induced QTc interval prolongation in women. Clin Pharmacol Ther 67:413–418

    Article  CAS  PubMed  Google Scholar 

  • Blenkinsopp A, Wilkie P, Wang M, Routledge PA (2007) Patient reporting of suspected adverse drug reactions: a review of published literature and international experience. Br J Clin Pharmacol 63:148–156

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu AW (2005) Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA 294:716–724

    Article  CAS  PubMed  Google Scholar 

  • BPAC (2010) A practical guide to stopping medicines in older people. BPJ 27:10–23

    Google Scholar 

  • BPAC NZ (2011) Antibiotics – choices for common infections [Internet]. New Zealand: BPACNZ. Cited 18 Jan 2013. Available: http://www.bpac.org.nz/resources/handbook/antibiotics/antibiotics_guide.asp

  • Brownfield ED, Bernhardt JM, Phan JL, Williams MV, Parker RM (2004) Direct-to-consumer drug advertisements on network television: an exploration of quantity, frequency, and placement. J Health Commun 9:491–497

    Article  PubMed  Google Scholar 

  • Buchanan FF, Myles PS, Cicuttini F (2011) Effect of patient sex on general anaesthesia and recovery. Br J Anaesth 106(6):832–839

    Article  CAS  PubMed  Google Scholar 

  • Buck MD, Atreja A, Brunker CP, Jain A, Suh TT, Palmer RM, Dorr DA, Harris CM, Wilcox AB (2009) Potentially inappropriate medication prescribing in outpatient practices: prevalence and patient characteristics based on electronic health records. Am J Geriatr Pharmacother 7:84–92

    Article  PubMed  Google Scholar 

  • Campbell AJ, Robertson MC, Gardner MM, Norton RN, Buchner DM (1999) Psychotropic medication withdrawal and a home-based exercise program to prevent falls: a randomized, controlled trial. J Am Geriatr Soc 47:850–853

    CAS  PubMed  Google Scholar 

  • CDC (1997) Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine: U.S. Department of Health and Human Services interim public health recommendations. MMWR 46:1061–1066

    Google Scholar 

  • CDC CFDCAP (2011) Preventing and managing chronic disease to improve the health of women and infants. Division of Reproductive Health

    Google Scholar 

  • Chilet-Rosell E, Ruiz-Cantero T, Fernández Sáez J, Álvarez-Dardet C (2013) Inequality in analgesic prescription in Spain a gender development issue. Gac Sanit 27:135–142

    Article  PubMed  Google Scholar 

  • Ciani O, Buyse M, Garside R, Pavey T, Stein K, Sterne JAC, Taylor RS (2013) Comparison of treatment effect sizes associated with surrogate and final patient relevant outcomes in randomised controlled trials: meta-epidemiological study. BMJ 346:f457

    Article  PubMed Central  PubMed  Google Scholar 

  • CIHI (2011) Seniors and the health care system: what is the impact of multiple chronic conditions? https://secure.cihi.ca/free_products/air-chronic_disease_aib_en.pdf. Canadian Institute for Health Information

  • Cochrane AL, Holland WW (1971) Validation of screening procedures. Br Med Bull 25:3–8

    Google Scholar 

  • Cohen LS, Altshuler LL, Harlow BL, Nonacs R, Newport DJ, Viguera AC, Suri R, Burt VK, Hendrick V, Reminick AM, Loughead A, Vitonis AF, Stowe ZN (2006) Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment. JAMA 295:499–507

    Article  CAS  PubMed  Google Scholar 

  • Coogan PF (2013) Calcium-channel blockers and breast cancer: a hypothesis revived. JAMA Intern Med 173:1637–1638

    Article  PubMed  Google Scholar 

  • Cotton P (1993) FDa lifts ban on women in early drug tests, will require companies to look for gender differences. JAMA 269:2067

    Article  CAS  PubMed  Google Scholar 

  • Cross C (2013) Introducing deprescribing into culture of medication. CMAJ 185(13):E606

    Article  PubMed Central  PubMed  Google Scholar 

  • Currie J (2003) Manufacturing addiction: the over-prescription of benzodiazepines and sleeping pills to women in Canada. British Columbia Centre of Excellence for Women’s Health [Policy Series]. http://bccewh.bc.ca/publicationsresources/publications/page/6/

  • Daw JR, Hanley GE, Greyson DL, Morgan SG (2011) Prescription drug use during pregnancy in developed countries: a systematic review. Pharmacoepidemiol Drug Saf 20:895–902

    PubMed Central  PubMed  Google Scholar 

  • Domecq C, Naranjo CA, Ruiz I, Busto U (1980) Sex-related variations in the frequency and characteristics of adverse drug reactions. Int J Clin Pharmacol Ther Toxicol 18:362–366

    CAS  PubMed  Google Scholar 

  • Drolet B, Simard C, Poirier P (2007) Impact of weight-loss medications on the cardiovascular system: focus on current and future anti-obesity drugs. Am J Cardiovasc Drugs 7:273–288

    Article  CAS  PubMed  Google Scholar 

  • Ebert SN, Liu XK, Woosley RL (1998) Female gender as a risk factor for drug-induced cardiac arrhythmias: evaluation of clinical and experimental evidence. J Womens Health 7:547–557

    Article  CAS  PubMed  Google Scholar 

  • Eisenberg DL, Stika C, Desai A, Baker D, Yost KJ (2010) Providing contraception for women taking potentially teratogenic medications: a survey of internal medicine physicians’ knowledge, attitudes and barriers. J Gen Intern Med 25:291–297

    Article  PubMed Central  PubMed  Google Scholar 

  • Fattinger K, Roos M, Vergeres P, Holenstein C, Kind B, Masche U, Stocker DN, Braunschweig S, Kullak-Ublick GA, Galeazzi RL, Follath F, Gasser T, Meier PJ (2000) Epidemiology of drug exposure and adverse drug reactions in two swiss departments of internal medicine. Br J Clin Pharmacol 49:158–167

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Field TS, Gilman BH, Subramanian S, Fuller JC, Bates DW, Gurwitz JH (2005) The costs associated with adverse drug events among older adults in the ambulatory setting. Med Care 43:1171–1176

    Article  PubMed  Google Scholar 

  • Figueras A, Capella D, Castel JM, Laorte JR (1994) Spontaneous reporting of adverse drug reactions to non-steroidal anti-inflammatory drugs. A report from the Spanish System of Pharmacovigilance, including an early analysis of topical and enteric-coated formulations. Eur J Clin Pharmacol 47:297–303

    Article  CAS  PubMed  Google Scholar 

  • Foxman B (2003) Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Dis Mon 49:53–70

    Article  PubMed  Google Scholar 

  • Fralick M, Juulink D et al (2014) Co-trimoxazole and sudden death in patients receiving inhibitors of renin-angiotensin system: population based study. BMJ 349:g6196

    Article  PubMed Central  PubMed  Google Scholar 

  • Gallagher P, O’Mahony D (2008) STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers’ criteria. Age Ageing 37:673–679

    Article  PubMed  Google Scholar 

  • Garfinkel D, Mangin D (2010) Feasibility study of a systematic approach for discontinuation of multiple medications in older adults: addressing polypharmacy. Arch Intern Med 170:1648–1654

    Article  PubMed  Google Scholar 

  • Garfinkel D, Zur-Gil S, Ben-Israel J (2007) The war against polypharmacy: a new cost-effective geriatric-palliative approach for improving drug therapy in disabled elderly people. Isr Med Assoc J 9:430–434

    PubMed  Google Scholar 

  • Geller SE, Koch A, Pellettieri B, Carnes M (2011) Inclusion, analysis, and reporting of sex and race/ethnicity in clinical trials: have we made progress? J Womens Health (Larchmt) 20:315–320

    Article  Google Scholar 

  • Gilbody SM, House AO, Sheldon TA (2005) Screening and case finding for depression. Cochrane Database Syst Rev (4):CD002792

    Google Scholar 

  • Golomb BA, Mcgraw JJ, Evans MA, Dimsdale JE (2007) Physician response to patient reports of adverse drug effects: implications for patient-targeted adverse effect surveillance. Drug Saf 30:669–675

    Article  PubMed  Google Scholar 

  • Gu Q, Dillon C, Burt VL (2010) Prescription drug use continues to increase: U.S. prescription drug data for 2007–2008, NCHS data brief. National Center for Health Statistics, Hyattsville (pp. 8)

    Google Scholar 

  • Hanlon JT, Schmader KE, Samsa GP, Weinberger M, Uttech KM, Lewis IK, Cohen HJ, Feussner JR (1992) A method for assessing drug therapy appropriateness. J Clin Epidemiol 45:1045–1051

    Article  CAS  PubMed  Google Scholar 

  • Harris RZ, Benet LZ, Schwartz JB (1995) Gender effects in pharmacokinetics and pharmacodynamics. Drugs 50:222–239

    Article  CAS  PubMed  Google Scholar 

  • Hausken AM, Skurtveit S, Rosvold EO, Bramness JG, Furu K (2007) Psychotropic drug use among persons with mental distress symptoms: a population-based study in Norway. Scand J Public Health 35:356–364

    Article  PubMed  Google Scholar 

  • Heinrich J (2001) Drug safety: most drugs withdrawn in recent years had greater health risks for women, GAO 01286R. United States General Accounting Office, Washington, DC

    Google Scholar 

  • Herxheimer A, Crombag R, Alves T (2010) Direct patient reporting of adverse drug reactions a fifteen-country survey & literature review. Health Action International (HAI) Europe

    Google Scholar 

  • Hilmer SN, Mager DE, Simonsick EM, Cao Y, Ling SM, Windham BG, Harris TB, Hanlon JT, Rubin SM, Shorr RI, Bauer DC, Abernethy DR (2007) A drug burden index to define the functional burden of medications in older people. Arch Intern Med 167:781–787

    Article  PubMed  Google Scholar 

  • Holmes HM, Hayley DC, Alexander GC, Sachs GA (2006) Reconsidering medication appropriateness for patients late in life. Arch Intern Med 166:605–609

    Article  PubMed  Google Scholar 

  • Iyer S, Naganathan V, Mclachlan AJ, Le Conteur DG (2008) Medication withdrawal trials in people aged 65 years and older. Drugs Aging 25:1021–1031

    Article  PubMed  Google Scholar 

  • Kando JC, Yonkers KA, Cole JO (1995) Gender as a risk factor for adverse events to medications. Drugs 50:1–6

    Article  CAS  PubMed  Google Scholar 

  • Katerndahl D, Wood R, Jaen CR (2011) Family medicine outpatient encounters are more complex than those of cardiology and psychiatry. J Am Board Fam Med 24(1):6–15

    Article  PubMed  Google Scholar 

  • Kendrick T, Hegarty K, Glaziou P (2008) Interpreting research findings to guide treatment in practice. BMJ 337. doi:10.1136/bmj.a1499

    Google Scholar 

  • Kennedy SH, Lam RW, Parikh SV, Patten SB, Ravindran AV (2009) Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. J Affect Disord 117(Suppl 1):S1–S2

    Article  PubMed  Google Scholar 

  • Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush AJ, Walters EE, Wang PS (2003) The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 289:3095–3105

    Article  PubMed  Google Scholar 

  • Klungel OH, DE Boer A, Paes AH, Seidell JC, Bakker A (1997) Sex differences in the pharmacological treatment of hypertension: a review of population-based studies. J Hypertens 15:591–600

    Article  CAS  PubMed  Google Scholar 

  • Klungel OH, De Boer A, Paes AH, Seidell JC, Bakker A (1998) Sex differences in antihypertensive drug use: determinants of the choice of medication for hypertension. J Hypertens 16:1545–1553

    Article  CAS  PubMed  Google Scholar 

  • Kost K, Singh S, Vaughan B, Trussell J, Bankole A (2008) Estimates of contraceptive failure from the 2002 National Survey of Family Growth. Contraception 77:10–21

    Article  PubMed Central  PubMed  Google Scholar 

  • Kravitz RL, Epstein RM, Feldman MD, Franz CE, Azari R, Wilkes MS, Hinton L, Franks P (2005) Influence of patients’ requests for direct-to-consumer advertised antidepressants: a randomized controlled trial. JAMA 293:1995–2002

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Lazarou J, Pomeranz BH, Corey PN (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279:1200–1205

    Article  CAS  PubMed  Google Scholar 

  • Makkar RR, Fromm BS, Steinman RT, Meissner MD, Lehmann MH (1993) Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. JAMA 270:2590–2597

    Article  CAS  PubMed  Google Scholar 

  • Malmusi D, Artazcoz L, Benach J, Borrell C (2012) Perception or real illness? How chronic conditions contribute to gender inequalities in self-rated health. Eur J Public Health 22:781–786

    Article  PubMed  Google Scholar 

  • Mangin D, Kerse N (2010) When is enough, enough? Stopping medicines in older people. Best Practice J 27:6–9

    Google Scholar 

  • Mangin D, Heath I, Jamoulle M (2012) Beyond diagnosis: responding to the comorbidity challenge. BMJ 44:e3526 (in press)

    Article  Google Scholar 

  • Martin RM, Biswas PN, Freemantle SN, Pearce GL, Mann RD (1998) Age and sex distribution of suspected adverse drug reactions to newly marketed drugs in general practice in England: analysis of 48 cohort studies. Br J Clin Pharmacol 46:505–511

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Mccarthy L, Dolovich L, Haq M, Thabane L, Kaczorowski J (2007) Frequency of risk factors that potentially increase harm from medications in older adults receiving primary care. Can J Clin Pharmacol 14:e283–e290

    CAS  PubMed  Google Scholar 

  • Mcgarvey WC, Singh D, Trevino SG (1996) Partial Achilles tendon ruptures associated with fluoroquinolone antibiotics: a case report and literature review. Foot Ankle Int 17:496–498

    Article  CAS  PubMed  Google Scholar 

  • Medco Health Solutions & Society for Women's Health Research (2012) More is sometimes less: women are prescribed a greater number of medications than men but take less of the drugs they need [Press release]. http://phx.corporate-ir.net/phoenix.zhtml?c=69641&p=irol-MedcoPressArticle&ID=1673845&highlight=%29

  • Mintzes B (2004) Drug regulatory failure in Canada: the case of Diane-35. Women and Health Protection. http://www.whp-apsf.ca/en/documents/diane35.html

  • Mintzes B (2010) “Ask your doctor”: women and direct-to-consumer advertising. In: Ford AR, Saibil D (eds) The push to prescribe: women and Canadian Drug Policy. Women’s Press, Toronto

    Google Scholar 

  • Mintzes B, Mangin D (2009) Opinion: direct-to-consumer advertising of prescription medicines: a counter argument. Future Med Chem 1:1555–1560

    Article  CAS  PubMed  Google Scholar 

  • Moore M, Yuen HM, Dunn N, Mullee MA, Maskell J, Kendrick T (2009) Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database. BMJ 339:b4361

    Article  Google Scholar 

  • Movin T, Gad A, Guntner P, Foldhazy Z, Rolf C (1997) Pathology of the Achilles tendon in association with ciprofloxacin treatment. Foot Ankle Int 18:297–299

    Article  CAS  PubMed  Google Scholar 

  • Munce SE, Robertson EK, Sansom SN, Stewart DE (2004) Who is portrayed in psychotropic drug advertisements? J Nerv Ment Dis 192:284–288

    Article  PubMed  Google Scholar 

  • NCCMH (2010) Depression: the treatment and management of depression in adults (Update). The British Psychological Society and the Royal College of Psychiatrists, Leicester/London. [Full guideline]

    Google Scholar 

  • Nelson MR, Reid CM, Krum H, Muir T, Ryan P, Mcneil JJ (2002) Predictors of normotension on withdrawal of antihypertensive drugs in elderly patients: prospective study in second Australian national blood pressure study cohort. BMJ 325:815–817

    Article  PubMed Central  PubMed  Google Scholar 

  • News C http://www.cbsnews.com/news/sex-matters-drugs-can-affect-sexes-differently/ [Online]

  • Nicholas R, Lee N, Roche A (2011) Pharmaceutical drug misuse in Australia: complex problems, balanced responses. National Centre for Education and Training on Addiction (NCETA), Adelaide

    Google Scholar 

  • Oates M (2003) Postnatal depression and screening: too broad a sweep? Br J Gen Pract 53:596–597

    PubMed Central  PubMed  Google Scholar 

  • Ochs HR, Greenblatt DJ, Divoll M, Abernethy DR, Feyerabend H, Dengler HJ (1981) Diazepam kinetics in relation to age and sex. Pharmacology 23:24–30

    Article  CAS  PubMed  Google Scholar 

  • OECD (2013) Health at a glance 2013: OECD indicators. OECD Publishing, Paris. http://dx.doi.org/10.1787/health_glance-2013-en

  • Ostini R, Jackson C, Hegney D, Tett SE (2011) How is medication prescribing ceased? A systematic review. Med Care 49:24–36

    Article  PubMed  Google Scholar 

  • PHARMAC – Pharmaceutical Management Agency. PHARMAC data relating to antidepressant prescribing and costs – 13 year trends and regional variation. PHARMAC, Wellington

    Google Scholar 

  • Pouyanne P, Haramburu F, Imbs JL, Bégaud B (2000) Admissions to hospital caused by adverse drug reactions: cross sectional incidence study. BMJ 320:1036

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Pratt L, Brody D, Gu Q (2011) Antidepressant use in persons aged 12 and over: United States, 2005–2008 NCHS Data Brief

    Google Scholar 

  • Rademaker M (2001) Do women have more adverse drug reactions? Am J Clin Dermatol 2:349–351

    Article  CAS  PubMed  Google Scholar 

  • Richards D, Toop L, Chambers ST, Sutherland M, Harris B, Ikram R, Jones M, Mcgeoch G, Peddie B (2002) Antibiotic resistance in uncomplicated urinary tract infection: problems with interpreting cumulative resistance rates from local community laboratories. N Z Med J 115:12–14

    PubMed  Google Scholar 

  • Richards D, Toop L, Chambers S, Fletcher L (2005) Response to antibiotics of women with symptoms of urinary tract infection but negative dipstick urine test results: double blind randomised controlled trial. BMJ 331:143–147

    Article  PubMed Central  PubMed  Google Scholar 

  • Roberts H, Redberg R (2013) Gender disparity in statin response: are statins less effective in women? Clin Lipidol 8:161–163

    Article  CAS  Google Scholar 

  • Sackett DL, Rosenberg WMC, Gray JAM, Haynes RB, Richardson WS (1996) Evidence based medicine: what it is and what it isn't. BMJ 312:71–72

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Salisbury C, Johnson L, Purdy S, Valderas JM, Montgomery AA (2011) Epidemiology and impact of multimorbidity in primary care: a retrospective cohort study. Br J Gen Pract 61:e12–e21

    Article  PubMed Central  PubMed  Google Scholar 

  • Schwarz EB, Maselli J, Norton M, Gonzales R (2005) Prescription of teratogenic medications in United States ambulatory practices. Am J Med 118:1240–1249

    Article  PubMed  Google Scholar 

  • Scott IA, Gray LC, Martin JH, Mitchell CA (2012) Minimizing inappropriate medications in older populations: a 10-step conceptual framework. Am J Med 125:529–537.e4

    Article  PubMed  Google Scholar 

  • Sharabi Y, Illan R, Kamari Y, Cohen H, Nadler M, Messerli FH, Grossman E (2002) Diuretic induced hyponatraemia in elderly hypertensive women. J Hum Hypertens 16:6331–6635

    Article  Google Scholar 

  • Sharma A, Chatterjee S, Arbab-Zadeh A, Goyal S, Lichstein E, Ghosh J, Aikat S (2013) Risk of serious atrial fibrillation and stroke with use of bisphosphonates: evidence from a meta-analysis. Chest 144:1311–1322

    Article  CAS  PubMed  Google Scholar 

  • Simoni-Wastila L (2000) The use of abusable prescription drugs: the role of gender. J Womens Health Gend Based Med 9:289–297

    Article  CAS  PubMed  Google Scholar 

  • Spigset O (1999) Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system. Drug Saf 20:277–287

    Article  CAS  PubMed  Google Scholar 

  • Steinkellner A, Chen W, Denison SE (2010) Adherence to oral contraception in women on category X medications. Am J Med 123:929–934.e1

    Article  PubMed  Google Scholar 

  • Steinman MA, Lund BC, Miao Y, Boscardin WJ, Kaboli PJ (2011) Geriatric conditions, medication use, and risk of adverse drug events in a predominantly male, older veteran population. J Am Geriatr Soc 59:615–621

    Article  PubMed Central  PubMed  Google Scholar 

  • Therapeutics Initiative: Evidence Based Drug Therapy (2005) Drugs for overactive bladder symptoms. Department of Pharmacology & Therapeutics, University of British Columbia, Vancouver

    Google Scholar 

  • Thorpe KE, Howard DH (2006) The rise in spending among Medicare beneficiaries: the role of chronic disease prevalence and changes in treatment intensity. Health Aff (Millwood) 25:w378–w388

    Article  Google Scholar 

  • Toop L, Richards D (2003) New Zealand deserves better. Direct-to-consumer advertising (DTCA) of prescription medicines in New Zealand: for health or for profit? N Z Med J 116:6

    Google Scholar 

  • Toop L, Richards D, Dowell T, Fraser T, Tilyard M, Arroll B (2003a) DTCA of prescription medicines in New Zealand: for health or for profit. Report update June 2003. Christchurch School of Medicine, Christchurch

    Google Scholar 

  • Toop L, Richards D, Dowell T, Tilyard M, Fraser T, Arroll B (2003b) Direct-to-consumer advertising of prescription drugs in New Zealand: For health or for profit? Report to the minister of health supporting the case for the ban of DTCA. University of Otago, Dunedin

    Google Scholar 

  • Tran C, Knowles SR, Liu BA, Shear NH (1998) Gender differences in adverse drug reactions. J Clin Pharmacol 38:1003–1009

    Article  CAS  PubMed  Google Scholar 

  • U. S. Food and Drug Administration (FDA) (2013) http://www.fda.gov/downloads/Drugs/DrugSafety/UCM335007.pdf

  • Van Der Klauw MM, Wilson JH, Stricker BH (1998) Drug-associated agranulocytosis: 20 years of reporting in The Netherlands (1974–1994). Am J Hematol 57:206–211

    Article  PubMed  Google Scholar 

  • Van Der Sijs H, Kowlesar R, Klootwijk APJ, Nelwan SP, Vulto AG, Van Gelder T (2009) Clinically relevant QTc prolongation due to overridden drug–drug interaction alerts: a retrospective cohort study. Br J Clin Pharmacol 67:347–354

    Article  PubMed Central  PubMed  Google Scholar 

  • Verbrugge LM, Steiner RP (1985) Prescribing drugs to men and women. Health Psychol 4:79–98

    Article  CAS  PubMed  Google Scholar 

  • Wester K, Jonsson AK, Spigset O, Druid H, Hagg S (2008) Incidence of fatal adverse drug reactions: a population based study. Br J Clin Pharmacol 65:573–579

    Article  PubMed Central  PubMed  Google Scholar 

  • Wolfe S (2012) The seven-year rule for safer prescribing. Aust Prescr 35:138–139

    Google Scholar 

  • Wong SLF, Wester F, Mol S, Römkens R, Lagro-Janssen T (2007) Utilisation of health care by women who have suffered abuse: a descriptive study on medical records in family practice. Br J Gen Pract 57:396–400

    PubMed Central  Google Scholar 

  • Yap YG, Camm AJ (2003) Drug induced QT prolongation and torsades de pointes. Heart 89:1363–1372

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Yonkers KA, Gotman N, Smith MV, Forray A, Belanger K, Brunetto WL, Lin H, Burkman RT, Zelop CM, Lockwood CJ (2011) Does antidepressant use attenuate the risk of a major depressive episode in pregnancy? Epidemiology 22:848–854

    PubMed Central  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dee Mangin .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Mangin, D. (2015). A Primary Care Perspective on Prescribing for Women. In: Harrison-Woolrych, M. (eds) Medicines For Women. Adis, Cham. https://doi.org/10.1007/978-3-319-12406-3_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-12406-3_14

  • Published:

  • Publisher Name: Adis, Cham

  • Print ISBN: 978-3-319-12405-6

  • Online ISBN: 978-3-319-12406-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics