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Economic and Environmental Evaluation of Recombinant Enzyme Production

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Recombinant Enzymes - From Basic Science to Commercialization

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Abstract

Economic and environmental evaluation on three different throughputs and comparison between these throughputs were presented. Comparisons are based on simulation of 10, 100 and 1000 kg/batch of recBromelain using SuperPro Designer v8.5. The economic analysis shows that 100 kg/batch gives the most competitive price and maintaining a sizeable profit gross margin of 28.21 %. A positive ROI of 18.41 % and minimal payback time of 5.43 years is predicted from 100 kg/batch of production. Environment analysis showed that total waste and energy consumption increased as production size increased. This simulation information will assist to predict the cost and environment impact at different size of productions.

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Authors and Affiliations

  1. Department of Biotechnology Engineering, Faculty of Engineering, International Islamic University Malaysia, P.O. Box 10, 50728, Kuala Lumpur, Malaysia

    Mohd Jamil Aizat Jamaluddin & Muhd. Ezza Faiez Othman

  2. Biomolecular and Bioprocess Engineering Research Unit, Department of Biotechnology Engineering, Faculty of Engineering, International Islamic University Malaysia, P.O. Box 10, 50728, Kuala Lumpur, Malaysia

    Azlin Suhaida Azmi, Dzun Noraini Jimat & Azura Amid

  3. Bioenvironmental Engineering Research Centre, Department of Biotechnology Engineering, Faculty of Engineering, International Islamic University Malaysia, P.O. Box 10, 50728, Kuala Lumpur, Malaysia

    Sarina Sulaiman

Authors
  1. Mohd Jamil Aizat Jamaluddin
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  2. Azlin Suhaida Azmi
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  3. Sarina Sulaiman
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  4. Dzun Noraini Jimat
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  5. Muhd. Ezza Faiez Othman
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  6. Azura Amid
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Corresponding author

Correspondence to Azlin Suhaida Azmi .

Editor information

Editors and Affiliations

  1. Department of Biotechnology Engineering Kulliyyah of Engineering, International Islamic University Malaysia, Kuala Lumpur, Malaysia

    Azura Amid

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Jamaluddin, M., Azmi, A., Sulaiman, S., Jimat, D., Othman, M., Amid, A. (2015). Economic and Environmental Evaluation of Recombinant Enzyme Production. In: Amid, A. (eds) Recombinant Enzymes - From Basic Science to Commercialization. Springer, Cham. https://doi.org/10.1007/978-3-319-12397-4_9

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