Abstract
Hunger perception and the decision to initiate a meal involve interactions between genetic, social, learned, environmental, circadian, and humoral cues. Several endogenous peptides with the ability to stimulate food intake have been identified in the feeding centers in the hypothalamus. Once feeding commences, the amount consumed is determined by factors involved in satiety perception. These factors involve combined effects of gastric distention and the release of peptide signals from enteroendocrine cells in the gastrointestinal tract. Satiety peptides include cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), oxyntomodulin, peptide YY (PYY), apolipoprotein A-IV, enterostatin, pancreatic polypeptide, glucagon, and amylin [1] (Fig. 2.1).
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González, H. (2016). Pathophysiology of Obesity. In: Managing Patients with Obesity. Adis, Cham. https://doi.org/10.1007/978-3-319-12331-8_2
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DOI: https://doi.org/10.1007/978-3-319-12331-8_2
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