New Insights into Mechanisms Underlying Generalized Reflex Seizures

  • Edoardo Ferlazzo
  • Domenico Italiano
  • Sara Gasparini
  • Giovanbattista Gaspare Tripodi
  • Tiziana D’Agostino
  • Umberto AgugliaEmail author
Part of the Contemporary Clinical Neuroscience book series (CCNE)


“Apparently generalized” reflex seizures usually occur in the setting of idiopathic generalized epilepsies. Several animal, neurophysiological and neuroimaging evidences strongly suggest that such reflex seizures should be considered as focal with quick secondary generalization through cortico-reticular or cortico-cortical pathways. The aim of this article is to highlight mechanisms underlying “apparently generalized” reflex seizures provoked by intermittent light stimulations, reading, thinking and praxis.


Intermittent light stimulations Reading Thinking Praxis Epilepsy 


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Edoardo Ferlazzo
    • 1
    • 2
  • Domenico Italiano
    • 3
  • Sara Gasparini
    • 1
    • 2
  • Giovanbattista Gaspare Tripodi
    • 2
  • Tiziana D’Agostino
    • 2
  • Umberto Aguglia
    • 1
    • 2
    Email author
  1. 1.Department of Medical and Surgical SciencesMagna Graecia UniversityCatanzaroItaly
  2. 2.Regional Epilepsy Centre“Bianchi-Melacrino-Morelli” HospitalReggio CalabriaItaly
  3. 3.Department of Clinical and Experimental MedicineUniversity of MessinaMessinaItaly

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