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Gold Nanoparticles in Biosensing Analyses

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Nanoparticles' Promises and Risks

Abstract

Monitoring biomolecular interactions has become a constituent element of various medical and clinical applications. The importance of measuring the biomolecular interaction is evident as a potpourri of sensing strategies is currently and continuously devised. One of the strategies that can immensely enhance the sensitivity of the interaction is the one mediated by nanoparticles. Among the various nanoparticles, gold nanoparticle (AuNP) is opted for due to its capacity to improve the sensitivity and selectivity of biomolecular interactions. In addition to this, AuNP is easy to be manufactured, chemically inert, have uniform dispersibility and are able to react with chemically modified biomolecules. In this overview, the roles adopted by AuNP in various biosensing applications are discussed.

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Acknowledgements

T.H. Tang was supported by a Universiti Sains Malaysia (USM) Research Grant (Number: 1001/CIPPT/813043). Y. Chen was supported by UM.C/625/1/HIR/MOHE/MED/16/5. T. Lakshmipriya was supported by the Research fellowship from USM.

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Authors and Affiliations

  1. Department of Oral Biology & Biomedical Sciences and OCRCC, Faculty of Dentistry, University of Malaya, 50603, Kuala Lumpur, Malaysia

    Subash C. B. Gopinath & Yeng Chen

  2. Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, 13200, Kepala Batas, Penang, Malaysia

    Subash C. B. Gopinath, Marimuthu Citartan, Thangavel Lakshmipriya & Thean-Hock Tang

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  1. Subash C. B. Gopinath
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  2. Marimuthu Citartan
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  3. Thangavel Lakshmipriya
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  4. Thean-Hock Tang
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  5. Yeng Chen
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Correspondence to Subash C. B. Gopinath .

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Editors and Affiliations

  1. Faculty of Physics, West University of Timisoara, Timisoara, Romania

    Mihai Lungu

  2. Faculty of Physics, West University of Timisoara, Timisoara, Romania

    Adrian Neculae

  3. Faculty of Physics, West University of Timisoara, Timisoara, Romania

    Madalin Bunoiu

  4. High Performance Computing Centre, West University of Timisoara, Timisoara, Romania

    Claudiu Biris

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Gopinath, S.C.B., Citartan, M., Lakshmipriya, T., Tang, TH., Chen, Y. (2015). Gold Nanoparticles in Biosensing Analyses. In: Lungu, M., Neculae, A., Bunoiu, M., Biris, C. (eds) Nanoparticles' Promises and Risks. Springer, Cham. https://doi.org/10.1007/978-3-319-11728-7_11

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