Abstract
The prevailing view is that elevated blood serum cholesterol is the primary controllable risk factor (as opposed to uncontrollable risk factors, such as age and genetics) in the development of atherosclerosis and coronary heart disease (CHD). Reports in the media state rather convincingly that lowering cholesterol dramatically reduces the risk of death from atherosclerosis and CHD. However, reducing cholesterol levels confer an absolute death benefit of 1/1,000 individuals when compared to individuals with elevated cholesterol. The benefits of lowering blood serum cholesterol continue to be a contentious and controversial issue in the medical community. Information presented to doctors and patients tends to be misleading and difficult to interpret. This is due, in large part, to the use of relative risks rather than absolute values when communicating information on cholesterol risks. In light of this situation, a unique graphic, functioning as a decision aid, has been developed to enable physicians and patients to jointly assess the benefits of lowering blood serum cholesterol numbers. Putting the complexities of risk analysis in terms patients can understand, means they patients will be able to make well-informed decisions about their health.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Murphy, S. L., Xu, J. Q., & Kochanek, K. D. (2013). Deaths: Final data for 2010. National Vital Statistics Report, 61(4), 1–117.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. (2001). Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adults Treatment Panel III). Journal of American Medical Association, 285(19), 2486–2497.
CarStone, N. J., Robinson, J., Lichtenstein, A. H., Bairey Merz, C. N., Lloyd-Jones, D. M., Blum, C. B., McBride, P., Eckel, R. H., Schwartz, J. S., Goldberg, A. C., Shero, S. T., Gordon, D., Smith, S. C., Jr., Levy, D., Watson, K., & Wilson, P. W. (2013). ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology, 63(25 Pt B), 2889–2934.
Ridker, P. M. (2003). High-sensitivity C-reactive protein and cardiovascular risk: Rationale for screening and primary prevention. American Journal of Cardiology, 92(4 supp 2), 17K–22K.
DeBakey, M. E., & Glaeser, D. H. (2000). Patterns of atherosclerosis: effects of risk factors on recurrence and survival – analysis of 11,890 cases with more than 25-year follow-up. American Journal of Cardiology, 85(9), 1045–1053.
Kannel, W. B., Dawber, T. R., Friedman, G. D., Glennon, W. E., & McNamara, P. M. (1964). Risk factors in coronary heart disease: An evaluation of several serum lipids as predictors of coronary heart disease; The Framingham Study. Annals of Internal Medicine, 61, 888–899.
Castelli, W. P., & Anderson, K. (1986). A population at risk: Prevalence of high cholesterol levels in hypersensitive patients in the Framingham Study. American Journal of Medicine, 80(2 supp1), 23–32.
World Health Organization (WHO) (1982). Prevention of coronary heart disease, report of a WHO expert committee. Technical Report Series No. 678, WHO, Geneva, 53 pp.
Kannel, W. B., Castelli, W. P., & Gordon, T. (1979). Cholesterol in the prediction of atherosclerotic disease: New perspectives based on the Framingham Study. Annals of Internal Medicine, 90(1), 85–91.
Kannel, W. B., Neaton, J. D., Wentworth, D., Thomas, H. E., Stamler, J., Hulley, S. B., & Kjelsberg, M. O. (1986). Overall and coronary heart disease mortality rates in relation to major risk factors in 325,348 men screened for the MRFIT (Multiple Risk Factor Intervention Trial). American Heart Journal, 112(4), 825–836.
Stamler, J., Wentworth, D., & Neaton, J. D. (1986). Is the relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT). Journal of American Medical Association, 256(2), 2823–2828.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Rifkin, E., Lazris, A. (2015). Cholesterol Screening. In: Interpreting Health Benefits and Risks. Springer, Cham. https://doi.org/10.1007/978-3-319-11544-3_15
Download citation
DOI: https://doi.org/10.1007/978-3-319-11544-3_15
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-11543-6
Online ISBN: 978-3-319-11544-3
eBook Packages: MedicineMedicine (R0)