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Anti-microbiological and Anti-infective Activities of Silver

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Silver Nanoparticle Applications

Part of the book series: Engineering Materials ((ENG.MAT.))

Abstract

Silver nanoparticles are the latest version of silver preparations that have been revived and tested as anti-microbials, particularly as an alternative to antibiotics since the emergence of drug resistant bacteria. Silver nanoparticles share commonalities with other silver preparations and other metallic nanoparticles, but also several significant differences in their interactions with microbes. Their mechanism of action is not completely understood but their potential utility has led to the high level of research activity to determine the safety and efficacy of these nanoparticles for clinical applications.

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Acknowledgments

Research in TF Mah’s laboratory has been supported by grants from Cystic Fibrosis Canada and the Natural Sciences and Engineering Research Council of Canada (NSERC). EIA thanks the University of Ottawa Heart Institute for the financial and scientific support (UOHI grant#1255). MG acknowledges funding from the Swedish Research Council and AFA Försäkring for research conducted within her laboratory.

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Authors and Affiliations

  1. Integrative Regenerative Medicine Centre, Department of Clinical and Experimental Medicine, Linköping University, 58185, Linköping, Sweden

    May Griffith

  2. Swedish Medical Nanoscience Centre, Department of Neuroscience, Karolinksa Institutet, Stockholm, Sweden

    May Griffith, Klas I. Udekwu & Spyridon Gkotzis

  3. Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada

    Thien-Fah Mah

  4. Bio-Nanomaterials Chemistry and Engineering Laboratory, Division of Cardiac Surgery, University of Ottawa Heart Institute, 40 Ruskin Street Rm H5229, Ottawa, K1Y 4W7, Canada

    Emilio I. Alarcon

  5. Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, Canada

    Emilio I. Alarcon

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  1. May Griffith
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  2. Klas I. Udekwu
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  3. Spyridon Gkotzis
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  4. Thien-Fah Mah
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  5. Emilio I. Alarcon
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Corresponding author

Correspondence to Emilio I. Alarcon .

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Editors and Affiliations

  1. Principal Investigator/Assistant Professor, Director Bio-nanomaterials Chemistry and Engineering Laboratory, Cardiac Surgery Research, University of Ottawa Heart Institute, Ottawa, Canada

    Emilio I. Alarcon

  2. Director, Integrative Regenerative Medicine Centre Linköping University, Linköping, Sweden

    May Griffith

  3. Swedish Medical Nanoscience Center, Karolinska Institutet, Stockholm, Sweden

    Klas I. Udekwu

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Griffith, M., Udekwu, K.I., Gkotzis, S., Mah, TF., Alarcon, E.I. (2015). Anti-microbiological and Anti-infective Activities of Silver. In: Alarcon, E., Griffith, M., Udekwu, K. (eds) Silver Nanoparticle Applications. Engineering Materials. Springer, Cham. https://doi.org/10.1007/978-3-319-11262-6_6

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