Abstract
Atherosclerosis is a chronic disease characterized by abnormal stiffness or loss of elasticity in the elastic and muscular medium- and large-sized arteries. Although arteriosclerosis is regarded etiologically as a multifactorial disease, the most frequent cause is the deposition or infiltration of lipid-rich material (atheroma plaques) or atherosclerosis in the arterial wall, induced by local and systemic factors. Hypercholesterolemia and especially high plasma concentrations of low density lipoproteins (LDL) are a significant risk factor for the premature onset of atherosclerosis and ischaemic heart disease.
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Lucena, J.S., Garamendi, P.M., Nombela-Franco, L. (2015). Coronary Atherosclerotic Disease. In: Lucena, J., García-Pavía, P., Suarez-Mier, M., Alonso-Pulpon, L. (eds) Clinico-Pathological Atlas of Cardiovascular Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-11146-9_5
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