Abstract
Uric acid is 11 times more soluble at pH 6.5 than at pH 5.0. For this reason, uric acid stone formation usually requires a persistently acid urinary pH. Conversely, raising the urinary pH with alkaline salts can frequently dissolve an existing calculus as long as free flow of urine past the stone can be established. This chapter outlines the clinical situations in which uric acid stones occur and provides a description of the medical therapy for dissolving and preventing this type of calculus.
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© 2015 Springer International Publishing Switzerland
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Rodman, J.S. (2015). Medical Management of Uric Acid Stones. In: Monga, M., Penniston, K., Goldfarb, D. (eds) Pocket Guide to Kidney Stone Prevention. Springer, Cham. https://doi.org/10.1007/978-3-319-11098-1_10
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DOI: https://doi.org/10.1007/978-3-319-11098-1_10
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