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Acquired Etiologies of Lacrimal System Obstructions

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The Lacrimal System

Abstract

The nasolacrimal drainage system is a unique physiologic system that is simple and elegant in design, yet is elaborate in the function of tear drainage, with the lacrimal pump and its anatomical construction. Epiphora may result when there is an excessive production of tears, hypersecretion, an inadequate evaporation and drainage, impairment of the lacrimal pump, stenosis or obstruction at any section of the lacrimal drainage system, or a consequence of any pathologic process that interferes with the physiology or continuity of the lacrimal drainage apparatus. Epiphora is determined by a balance between tear production and tear drainage and not by the absolute function or dysfunction or either. It can be isolated or may involve multiple levels, at any level of the lacrimal drainage system.

You as the physician must be able to determine the cause of the epiphora, and the appropriate treatment plan. Your understanding and knowledge of the anatomy and pathophysiology of the lacrimal drainage system will help you arrive at the correct diagnosis of the cause of the epiphora, and then be able to provide the correct and successful treatment plan.

I hope that the following classification system, the discussion of the location and cause of nasolacrimal duct stenosis and/or occlusion and the etiologic classification system, as discussed in this chapter, will provide a useful mechanism in the formulation of a differential diagnosis and help to develop the appropriate evaluation and treatment plan for each and all of your individual patients.

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References

  1. McCormick SA, Linberg JV. Pathology of the nasolacrimal duct obstruction. Contemp Issues Ophthalmol Lacrimal Surg. 1988;5:169–202.

    Google Scholar 

  2. Zhuang L, Sylvester CL, Simons JP. Bilateral congenital lacrimal fistulae: a case report and review of the literature. Laryngoscope. 2010;120 Suppl 4:S230.

    Article  PubMed  Google Scholar 

  3. Barton K, Monroy D, Nave A, Pflugfelder SC. Inflammatory cytokines in tears of patients with ocular rosacea. Ophthalmology. 1997;104:1868–74.

    Article  PubMed  CAS  Google Scholar 

  4. Van Santvliet L, Ludwig A. Determinants of eye drop size. Surv Ophthalmol. 2004;49(2):197–213.

    Article  PubMed  Google Scholar 

  5. Shimazaki J, Sakata M, Tsubota K. Ocular surface changes and discomfort in patients with meibomian gland dysfunction. Arch Ophthalmol. 1995;113:1266–70.

    Article  PubMed  CAS  Google Scholar 

  6. Lin PY, Tsai SY, et al. Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study. Ophthalmology. 2003;110:1096–101.

    Article  PubMed  Google Scholar 

  7. Paulsen FP, Thale AB, Maune S, Tillmann BN. New insight into the pathophysiology of primary acquired dacryostenosis. Ophthalmology. 2001;108(12):2329–36.

    Article  PubMed  CAS  Google Scholar 

  8. Burns JA, Cahill KV. Modified Kinosian dacryosystorhinostomy: a review of 122 cases. Ophthalmic Surg. 1985;16:710–6.

    PubMed  CAS  Google Scholar 

  9. Bartley GB. Acquired lacrimal obstruction: an etiologic classification system, case report, and a review of the literature. Part 1. Ophthal Plast Reconstr Surg. 1992;8(4):237–42.

    Article  PubMed  CAS  Google Scholar 

  10. Lyons CJ, Rosser PM, Welham RA. The management of puntal agenesis. Ophthalmology. 1993;100(12):1851–5.

    Article  PubMed  CAS  Google Scholar 

  11. Rose GE. The giant fornix syndrome: an unrecognized cause of chronic, relapsing, grossly purulent conjunctivitis. Ophthalmology. 2004;111:1539–45.

    Article  PubMed  Google Scholar 

  12. Maguire LJ, Bartley GB. Complications associated with the new smaller size Freeman punctal plug. Arch Ophthalmol. 1989;107:961–2.

    Article  PubMed  CAS  Google Scholar 

  13. Nelson C. Complications of Freeman plug. Arch Ophthalmol. 1991;101:923–4.

    Article  Google Scholar 

  14. Mahapatra AK, Suri A. Anterior Encephaloceles: a study of 92 cases. Pediatr Neurosurg. 2002;36:113–8.

    Article  PubMed  CAS  Google Scholar 

  15. Knop E, Knop N. Lacrimal drainage-associated lymphoid tissue (LDALT): a part of the human mucosal immune system. Invest Ophthalmol Vis Sci. 2001;42:566–74.

    PubMed  CAS  Google Scholar 

  16. Paulsen F, Corfield AP, Hinz M, et al. Characterization of mucins in human lacrimal sac and nasolacrimal duct. Invest Ophthalmol Vis Sci. 2003;44(5):1807–13.

    Article  PubMed  Google Scholar 

  17. Mauriello JA, Palydowycz S, DeLuca J. Clinicopathologic study of lacrimal sac and nasal mucosa in 44 patients with complete acquired nasolacrimal duct obstruction. Ophthal Plast Reconstr Surg. 1992;8(1):13–21.

    Article  PubMed  Google Scholar 

  18. Francisca FC, Carvalho AC, Francisco VF, et al. Evaluation of 1000 lacrimal ducts by dacryocystography. Br J Ophthalmol. 2007;91(1):43–6.

    Article  Google Scholar 

  19. Anderson NG, Wojno TH, Grossniklaus HE. Clinicopathologic findings from lacrimal sac biopsy specimens obtained during dacryocystorhinostomy. Ophthal Plast Reconstr Surg. 2003;19:173–6.

    Article  PubMed  Google Scholar 

  20. Zeitz HJ. Bronchial asthma, nasal polyps, and aspirin sensitivity: Samter’s syndrome. Clin Chest Med. 1988;9:567–76.

    PubMed  CAS  Google Scholar 

  21. Blicker JA, Buffam FV. Lacrimal sac, conjunctival, and nasal culture results in dacryocystorhinostomy patients. Ophthal Plast Reconstr Surg. 1993;9(1):43–6.

    Article  PubMed  CAS  Google Scholar 

  22. Baddini-Caramelli C, Matayoshe S, Moura EM, et al. Chronic dacryocystitis in American mucocutaneous Leishmaniasis. Ophthal Plast Reconstr Surg. 2001;17:48–52.

    Article  PubMed  CAS  Google Scholar 

  23. Yazici B, Hammad AM, Meyer DR. Lacrimal sac dacryoliths: predictive factors and clinical characteristics. Ophthalmology. 2001;108(7):1308–12.

    Article  PubMed  CAS  Google Scholar 

  24. Mauriello JA, Stabile C, Wagner RS. Dacryocystitis following Kawasaki’s disease. Ophthal Plast Reconstr Surg. 1986;2(4):209–11.

    Article  PubMed  Google Scholar 

  25. Bartley GB. Acquired lacrimal drainage obstruction: an etiologic classification system, case reports, and a review of the literature. Part 2. Ophthal Plast Reconstr Surg. 1992;8(4):243–49.

    Article  PubMed  CAS  Google Scholar 

  26. Ni C, D’Amico DJ, Fan CQ, et al. Tumors of the lacrimal sac: a clinicopathological analysis of 82 cases. Int Ophthalmol Clin. 1982;22:121–40.

    Article  PubMed  CAS  Google Scholar 

  27. Ozcan KM, Ozdas T, Baran H, et al. Hemolacria: case report. Int J Pediatr Otorhinolaryngol. 2013;77(1):137–8.

    Article  PubMed  Google Scholar 

  28. Madreperla SA, Gree WR, Daniel R, Shah KW. Human papillomavirus in primary epithelia tumors of the lacrimal sac. Ophthalmology. 1993;100:569–73.

    Article  PubMed  CAS  Google Scholar 

  29. Bartley GB. Acquired lacrimal drainage obstruction: an etiologic classification system, case report, and a review of the literature. Part 3. Ophthal Plast Reconstr Surg. 1993;9(1):11–26.

    Article  PubMed  CAS  Google Scholar 

  30. Jakobiec FA, Zakka FR, Papakostas TD, Fay F. Angiomyofibroma of the orbit: a hybrid of vascular leiomyoma and cavernous hemangioma. Ophthal Plast Reconstr Surg. 2012;28(6):438–45.

    Article  PubMed  Google Scholar 

  31. Leib ML, Chynn EW, Michalos P, Schubert HD, Leib EJ. Neurilemmoma of the anterior ethmoidal nerve encroaching upon the nasolacrimal duct. Br J Ophthalmol. 1992;76:750–2.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  32. Lyon DB, Dortzbach RK, Lemke BN, Gonnering RS. Canalicular stenosis following probing for congenital nasolacrimal duct obstruction. Ophthalmic Surg. 1991;22:228–32.

    PubMed  CAS  Google Scholar 

  33. Young JDH, MacEwen CJ, Ogston SA. Congenital nasolacrimal duct obstruction in the second year of life, a multicenter trial of management. Eye (Lond). 1996;10:484–91.

    Article  Google Scholar 

  34. White WL, Bartley GB, Hawes MJ, et al. Iatrogenic complications related to the use of Herrick Lacrimal Plugs. Ophthalmology. 2001;10:1835–7.

    Article  Google Scholar 

  35. McNab AA. Lacrimal canalicular obstruction associated with topical ocular medication. Aust N Z J Ophthalmol. 1998;26:219–23.

    Article  PubMed  CAS  Google Scholar 

  36. Khong JJ, Muecke J. Complications of Mitomycin C therapy in 100 eyes with ocular surface neoplasia. Br J Ophthalmol. 2006;90:819–22.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  37. Koop ED, Seregard A, Selva D. Punctal–canalicular stenosis associated with mitomycin-C for corneal epithelial dysplasia. Am J Ophthalmol. 2003;136:746–7.

    Article  Google Scholar 

  38. Esmaeli B, Valero V, Ahmadi MA, Booser D. Canalicular stenosis secondary to docetaxel (taxotere): a newly recognized side effect. Ophthalmology. 2001;108:994–5.

    Article  PubMed  CAS  Google Scholar 

  39. Esmaeli B, Burnstine MA, Ahmadi MA, Prieto VG. Docetaxel-induced histologic changes in the lacrimal sac and nasal mucosa. Ophthal Plast Reconstr Surg. 2003;19(4):305–8.

    Article  PubMed  Google Scholar 

  40. Lovato AA, Char DH, Castro JR, Kroll SM. The effect of silicone nasolacrimal intubation on epiphora after helium ion irradiation of uveal melanomas. Am J Ophthalmol. 1989;108:431–4.

    Article  PubMed  CAS  Google Scholar 

  41. Burns JA, Morgenstern KE, Cahill KV, et al. Nasolacrimal obstruction secondary to I131 therapy. Ophthal Plast Reconstr Surg. 2004;20:126–9.

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Daniel P. Schaefer M.D., F.A.C.S. .

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Schaefer, D.P. (2015). Acquired Etiologies of Lacrimal System Obstructions. In: Cohen, A., Mercandetti, M., Brazzo, B. (eds) The Lacrimal System. Springer, Cham. https://doi.org/10.1007/978-3-319-10332-7_5

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  • DOI: https://doi.org/10.1007/978-3-319-10332-7_5

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