Abstract
The nasolacrimal drainage system is a unique physiologic system that is simple and elegant in design, yet is elaborate in the function of tear drainage, with the lacrimal pump and its anatomical construction. Epiphora may result when there is an excessive production of tears, hypersecretion, an inadequate evaporation and drainage, impairment of the lacrimal pump, stenosis or obstruction at any section of the lacrimal drainage system, or a consequence of any pathologic process that interferes with the physiology or continuity of the lacrimal drainage apparatus. Epiphora is determined by a balance between tear production and tear drainage and not by the absolute function or dysfunction or either. It can be isolated or may involve multiple levels, at any level of the lacrimal drainage system.
You as the physician must be able to determine the cause of the epiphora, and the appropriate treatment plan. Your understanding and knowledge of the anatomy and pathophysiology of the lacrimal drainage system will help you arrive at the correct diagnosis of the cause of the epiphora, and then be able to provide the correct and successful treatment plan.
I hope that the following classification system, the discussion of the location and cause of nasolacrimal duct stenosis and/or occlusion and the etiologic classification system, as discussed in this chapter, will provide a useful mechanism in the formulation of a differential diagnosis and help to develop the appropriate evaluation and treatment plan for each and all of your individual patients.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
McCormick SA, Linberg JV. Pathology of the nasolacrimal duct obstruction. Contemp Issues Ophthalmol Lacrimal Surg. 1988;5:169–202.
Zhuang L, Sylvester CL, Simons JP. Bilateral congenital lacrimal fistulae: a case report and review of the literature. Laryngoscope. 2010;120 Suppl 4:S230.
Barton K, Monroy D, Nave A, Pflugfelder SC. Inflammatory cytokines in tears of patients with ocular rosacea. Ophthalmology. 1997;104:1868–74.
Van Santvliet L, Ludwig A. Determinants of eye drop size. Surv Ophthalmol. 2004;49(2):197–213.
Shimazaki J, Sakata M, Tsubota K. Ocular surface changes and discomfort in patients with meibomian gland dysfunction. Arch Ophthalmol. 1995;113:1266–70.
Lin PY, Tsai SY, et al. Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study. Ophthalmology. 2003;110:1096–101.
Paulsen FP, Thale AB, Maune S, Tillmann BN. New insight into the pathophysiology of primary acquired dacryostenosis. Ophthalmology. 2001;108(12):2329–36.
Burns JA, Cahill KV. Modified Kinosian dacryosystorhinostomy: a review of 122 cases. Ophthalmic Surg. 1985;16:710–6.
Bartley GB. Acquired lacrimal obstruction: an etiologic classification system, case report, and a review of the literature. Part 1. Ophthal Plast Reconstr Surg. 1992;8(4):237–42.
Lyons CJ, Rosser PM, Welham RA. The management of puntal agenesis. Ophthalmology. 1993;100(12):1851–5.
Rose GE. The giant fornix syndrome: an unrecognized cause of chronic, relapsing, grossly purulent conjunctivitis. Ophthalmology. 2004;111:1539–45.
Maguire LJ, Bartley GB. Complications associated with the new smaller size Freeman punctal plug. Arch Ophthalmol. 1989;107:961–2.
Nelson C. Complications of Freeman plug. Arch Ophthalmol. 1991;101:923–4.
Mahapatra AK, Suri A. Anterior Encephaloceles: a study of 92 cases. Pediatr Neurosurg. 2002;36:113–8.
Knop E, Knop N. Lacrimal drainage-associated lymphoid tissue (LDALT): a part of the human mucosal immune system. Invest Ophthalmol Vis Sci. 2001;42:566–74.
Paulsen F, Corfield AP, Hinz M, et al. Characterization of mucins in human lacrimal sac and nasolacrimal duct. Invest Ophthalmol Vis Sci. 2003;44(5):1807–13.
Mauriello JA, Palydowycz S, DeLuca J. Clinicopathologic study of lacrimal sac and nasal mucosa in 44 patients with complete acquired nasolacrimal duct obstruction. Ophthal Plast Reconstr Surg. 1992;8(1):13–21.
Francisca FC, Carvalho AC, Francisco VF, et al. Evaluation of 1000 lacrimal ducts by dacryocystography. Br J Ophthalmol. 2007;91(1):43–6.
Anderson NG, Wojno TH, Grossniklaus HE. Clinicopathologic findings from lacrimal sac biopsy specimens obtained during dacryocystorhinostomy. Ophthal Plast Reconstr Surg. 2003;19:173–6.
Zeitz HJ. Bronchial asthma, nasal polyps, and aspirin sensitivity: Samter’s syndrome. Clin Chest Med. 1988;9:567–76.
Blicker JA, Buffam FV. Lacrimal sac, conjunctival, and nasal culture results in dacryocystorhinostomy patients. Ophthal Plast Reconstr Surg. 1993;9(1):43–6.
Baddini-Caramelli C, Matayoshe S, Moura EM, et al. Chronic dacryocystitis in American mucocutaneous Leishmaniasis. Ophthal Plast Reconstr Surg. 2001;17:48–52.
Yazici B, Hammad AM, Meyer DR. Lacrimal sac dacryoliths: predictive factors and clinical characteristics. Ophthalmology. 2001;108(7):1308–12.
Mauriello JA, Stabile C, Wagner RS. Dacryocystitis following Kawasaki’s disease. Ophthal Plast Reconstr Surg. 1986;2(4):209–11.
Bartley GB. Acquired lacrimal drainage obstruction: an etiologic classification system, case reports, and a review of the literature. Part 2. Ophthal Plast Reconstr Surg. 1992;8(4):243–49.
Ni C, D’Amico DJ, Fan CQ, et al. Tumors of the lacrimal sac: a clinicopathological analysis of 82 cases. Int Ophthalmol Clin. 1982;22:121–40.
Ozcan KM, Ozdas T, Baran H, et al. Hemolacria: case report. Int J Pediatr Otorhinolaryngol. 2013;77(1):137–8.
Madreperla SA, Gree WR, Daniel R, Shah KW. Human papillomavirus in primary epithelia tumors of the lacrimal sac. Ophthalmology. 1993;100:569–73.
Bartley GB. Acquired lacrimal drainage obstruction: an etiologic classification system, case report, and a review of the literature. Part 3. Ophthal Plast Reconstr Surg. 1993;9(1):11–26.
Jakobiec FA, Zakka FR, Papakostas TD, Fay F. Angiomyofibroma of the orbit: a hybrid of vascular leiomyoma and cavernous hemangioma. Ophthal Plast Reconstr Surg. 2012;28(6):438–45.
Leib ML, Chynn EW, Michalos P, Schubert HD, Leib EJ. Neurilemmoma of the anterior ethmoidal nerve encroaching upon the nasolacrimal duct. Br J Ophthalmol. 1992;76:750–2.
Lyon DB, Dortzbach RK, Lemke BN, Gonnering RS. Canalicular stenosis following probing for congenital nasolacrimal duct obstruction. Ophthalmic Surg. 1991;22:228–32.
Young JDH, MacEwen CJ, Ogston SA. Congenital nasolacrimal duct obstruction in the second year of life, a multicenter trial of management. Eye (Lond). 1996;10:484–91.
White WL, Bartley GB, Hawes MJ, et al. Iatrogenic complications related to the use of Herrick Lacrimal Plugs. Ophthalmology. 2001;10:1835–7.
McNab AA. Lacrimal canalicular obstruction associated with topical ocular medication. Aust N Z J Ophthalmol. 1998;26:219–23.
Khong JJ, Muecke J. Complications of Mitomycin C therapy in 100 eyes with ocular surface neoplasia. Br J Ophthalmol. 2006;90:819–22.
Koop ED, Seregard A, Selva D. Punctal–canalicular stenosis associated with mitomycin-C for corneal epithelial dysplasia. Am J Ophthalmol. 2003;136:746–7.
Esmaeli B, Valero V, Ahmadi MA, Booser D. Canalicular stenosis secondary to docetaxel (taxotere): a newly recognized side effect. Ophthalmology. 2001;108:994–5.
Esmaeli B, Burnstine MA, Ahmadi MA, Prieto VG. Docetaxel-induced histologic changes in the lacrimal sac and nasal mucosa. Ophthal Plast Reconstr Surg. 2003;19(4):305–8.
Lovato AA, Char DH, Castro JR, Kroll SM. The effect of silicone nasolacrimal intubation on epiphora after helium ion irradiation of uveal melanomas. Am J Ophthalmol. 1989;108:431–4.
Burns JA, Morgenstern KE, Cahill KV, et al. Nasolacrimal obstruction secondary to I131 therapy. Ophthal Plast Reconstr Surg. 2004;20:126–9.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Schaefer, D.P. (2015). Acquired Etiologies of Lacrimal System Obstructions. In: Cohen, A., Mercandetti, M., Brazzo, B. (eds) The Lacrimal System. Springer, Cham. https://doi.org/10.1007/978-3-319-10332-7_5
Download citation
DOI: https://doi.org/10.1007/978-3-319-10332-7_5
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-10331-0
Online ISBN: 978-3-319-10332-7
eBook Packages: MedicineMedicine (R0)