Abstract
A 46 year old African American female presents for evaluation of white spots on both her arms that have been spreading. She says that she first noted the spots 2 years ago. There were initially two spots on her right arm and three on her left arm. They have combined and become larger. Before this, she says she had perfect skin and did not even have acne as a teenager. She denies any pain or trauma to the areas. She says she has tried to scrub the spots when showering but it has not helped. She has also applied several name brand lotions to the spots daily. While her skin has remained moisturized, her lesions have not improved. She is very self-conscious about the lesions and is afraid that it may be “some type of cancer.” She tries to wear long sleeve shirts to avoid having her arms seen because she feels it makes her look deformed. She is upset because the weather is getting warm but she is embarrassed to wear short sleeve t-shirts. She does feel she gained weight over the last several months and becomes fatigued very quickly. She denies any fever, chills, headache, shortness of breath, palpitations, or excessive sweating. She feels her menses have been less frequent. She has no allergies and does not take any medications.
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References
Wolff K, Johnson RA, Suurmond D. Section 13: Pigmentary disorders – vitiligo. Fitzpatrick’s color atlas & synopsis of clinical dermatology. 6th ed. New York: McGraw-Hill; 2009.
Wolff K, et al. Fitzpatrick’s dermatology in general medicine. 7th ed. New York: McGraw Hill; 2007. p. 616–21.
Kopera D. Historical aspects and definition of vitiligo. Clin Dermatol. 1997;15(6):841–3.
Halder RM, Taliaferro SJ. Vitiligo. In: Wolff K et al., editors. Fitzpatrick’s dermatology in general medicine. 7th ed. New York: McGraw-Hill; 2008. Chap. 72.
Bolognia JL, Jorizzo JL, Rapini R. Dermatology. 2nd ed. St. Louis: Mosby Elsevier; 2008. p. 1023–48.
Gauthier Y. The importance of Koebner’s phenomenon in induction of vitiligo vulgaris lesions. Eur J Dermatol. 1995;5:704–8.
James WD, et al. Andrews’ diseases of the skin: clinical dermatology. London: Saunders; 2011.
Westerhof W, Nieuweboer-Krobotova L. Treatment of vitiligo with UV-B radiation vs topical psoralen plus UV-A. Arch Dermatol. 1997;133(12):1525–8.
Scherschun L, Kim JJ, Lim HW. Narrow-band ultraviolet B is a useful and well-tolerated treatment for vitiligo. J Am Acad Dermatol. 2001;44(6):999–1003.
Gupta S, Honda S, Kumar B. A novel scoring system for evaluation of results of autologous transplantation methods in vitiligo. Indian J Dermatol Venereol Leprol. 2002;68(1):33–7.
Mosher DB, Parrish JA, Fitzpatrick TB. Monobenzylether of hydroquinone. A retrospective study of treatment of 18 vitiligo patients and a review of the literature. Br J Dermatol. 1977;97(6):669–79.
Bolognia JL, LaPia K, Somma S. Depigmentation therapy. Dermatol Ther. 2001;14:29–34.
Tahir MA, et al. Current remedies for vitiligo. Autoimmun Rev. 2010;9(7):516–20.
Panda AK. The medico historical perspective of vitiligo (Switra). Bull Indian Inst Hist Med Hyderabad. 2005;35(1):41–6.
Reyes E, Jaén P, de las Heras E, Carrión F, Alvarez-Mon M, de Eusebio E, et al. Systemic immunomodulatory effects of polypodium leucotomos as an adjuvant to PUVA therapy in generalized vitiligo: a pilot study. J Dermatol Sci. 2006;41:213–16.
Faas L, et al. In vivo evaluation of piperine and synthetic analogues as potential treatments for vitiligo using a sparsely pigmented mouse model. Br J Dermatol. 2008;158(5):941–50.
Felsten ML, Alikhan A, Petronic-Rosic V. Vitiligo: A comprehensive overview – Part II: treatment options and approach to treatment. J Am Acad Dermatol. 2011;65(3):493–514.
Awad SS. Chinese cupping: a simple method to obtain epithelial grafts for the management of resistant localized vitiligo. Dermatol Surg. 2008;34(9):1186–92.
Czarnowicki T, et al. Dead Sea climatotherapy for vitiligo: a retrospective study of 436 patients. J Eur Acad Dermatol Venereol. 2011;25(8):959–63.
Schallreuter KU, et al. Rapid initiation of repigmentation in vitiligo with Dead Sea climatotherapy in combination with pseudocatalase (PC-KUS). Int J Dermatol. 2002;41(8):482–7.
Parsad D, Pandhi R, Juneja A. Effectiveness of oral Ginkgo biloba in treating limited, slowly spreading vitiligo. Clin Exp Dermatol. 2003;28(3):285–7.
Szczurko O, et al. Ginkgo biloba for the treatment of vitilgo vulgaris: an open label pilot clinical trial. BMC Complement Altern Med. 2011;11:21.
Akyol M, Celik VK, Ozcelik S, Polat M, Marufihah M, Atalay A. The effects of vitamin E on the skin lipid peroxidation and the clinical improvement in vitiligo patients treated with PUVA. Eur J Dermatol. 2002;12:24–6.
Rojas-Urdaneta JE, Poleo-Romero AG. Evaluation of an antioxidant and mitochondria-stimulating cream formula on the skin of patients with stable common vitiligo. [Spanish]. Investigacion Clinica. 2007;48:21–31.
Teschke R, Bahre R. Severe hepatotoxicity by Indian ayurvedic herbal products: a structured causality assessment. Ann Hepatol. 2009;8(3):258–66.
Szczurko O, Boon HS. A systematic review of natural health product treatment for vitiligo. BMC Dermatol. 2008;8:2.
Antivitiligo.com [Internet]. Pakistan: TrueHerbal laboratories; c2009 [updated 22 Apr 2009; cited 12 Dec 2013]. http://www.antivitiligo.com/
Vitilo Lotion [Internet]. India: Elder healthcare; c2013 [updated 2013; cited 12 Dec 2013]. http://www.elderhealthcare.in/vitilo.aspx-
BonzaStrong [Internet]. Mukesh medical hall; c2009 [updated 2013; cited 12 Dec 2013]. http://mukeshmedicalhall.com/contact-us.html
Nordlund JJ, Melagenina HR. An analysis of published and other available data. Dermatologica. 1990;181(1):1–4.
Zhao D, et al. Melagenine modulates proliferation and differentiation of melanoblasts. Int J Mol Med. 2008;22(2):193–7.
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Madan, R., Rupani, R. (2015). A 46 Year Old African American Woman with White Spots. In: Clinical Cases in Integrative Dermatology. Clinical Cases in Dermatology, vol 4. Springer, Cham. https://doi.org/10.1007/978-3-319-10244-3_5
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