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A 60-Year-Old Woman with Pemphigus Vulgaris Refractory to High-Dose Prednisone

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Clinical Cases in Autoimmune Blistering Diseases

Part of the book series: Clinical Cases in Dermatology ((CLIDADE,volume 5))

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Abstract

A 60-year-old woman weighing 55 kg presented to the clinic with a 4-month history of sores in her mouth and on her chest. Skin biopsy showed a sparse, superficial, perivascular dermatitis with suprabasal acantholysis. Direct immunofluorescence was positive for IgG and C3 in an intercellular pattern. The patient was started on prednisone at 80 mg per day by an outside dermatologist 1 month prior to referral. Her disease flared when she attempted to taper the prednisone below 80 mg per day, with painful erosions that interfered with eating on her left and right buccal mucosa, and on the left side of her mouth, as well as extensive erosions on her chest and back, and some erosions on her legs.

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Correspondence to Victoria P. Werth M.D. .

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Robinson, E.S., Werth, V.P. (2015). A 60-Year-Old Woman with Pemphigus Vulgaris Refractory to High-Dose Prednisone. In: Murrell, D. (eds) Clinical Cases in Autoimmune Blistering Diseases. Clinical Cases in Dermatology, vol 5. Springer, Cham. https://doi.org/10.1007/978-3-319-10148-4_9

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  • DOI: https://doi.org/10.1007/978-3-319-10148-4_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-10147-7

  • Online ISBN: 978-3-319-10148-4

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