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Malaria Diagnosis, Therapy, Vaccines, and Vector Control

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Human and Mosquito Lysozymes

Abstract

Malaria remains a massive public health problem in the world affecting more than 200 million people and causing 600,000 deaths every year, mostly in children under 5 years of age. Malaria control strategies include treatment of diagnosis-confirmed patients with artemisinin-based combination therapy, protection of individuals with insecticide-treated bed nets, and indoor residual spraying to fight against the vector. However, the emergence of artemisinin resistance in P. falciparum in Southeast Asia and the development of insecticide resistance in mosquitoes are putting these control tools at risk. An effective vaccine could be the tool to reach the eradication goal. However, only the RTS,S/AS01 vaccine is likely to be launched in 2015, despite its effectiveness is modest.

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Authors and Affiliations

  1. Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università degli Studi di Milano, Milan, Italy

    Nicoletta Basilico

  2. Dipartimento di Medicina Sperimentale, Università degli Studi di Perugia, Perugia, Italy

    Roberta Spaccapelo

  3. Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy

    Sarah D’Alessandro

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  1. Nicoletta Basilico
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  2. Roberta Spaccapelo
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Correspondence to Nicoletta Basilico .

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  1. Neuroscience, University of Torino, Torino, Italy

    Mauro Prato

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Basilico, N., Spaccapelo, R., D’Alessandro, S. (2015). Malaria Diagnosis, Therapy, Vaccines, and Vector Control. In: Prato, M. (eds) Human and Mosquito Lysozymes. Springer, Cham. https://doi.org/10.1007/978-3-319-09432-8_2

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