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Animal Models of Liver Cancer

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Hepatocellular Carcinoma

Part of the book series: SpringerBriefs in Cancer Research ((BRIEFSCANCER))

Abstract

To understand the cellular mechanisms of HCC, and to develop novel therapeutic options for HCC, a number of animal models have been developed over the years. These include rodent, rabbit, swine, and primate model systems. While these animal models have helped to understand HCC to some extent, an ideal model system that mimics the human condition in terms of physiology, etiology and clinical setting is still missing. Towards this goal, there is a greater need than ever to develop a novel animal model that will recapitulate the human condition in its entirety.

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Aravalli, R.N., Steer, C.J. (2014). Animal Models of Liver Cancer. In: Hepatocellular Carcinoma. SpringerBriefs in Cancer Research. Springer, Cham. https://doi.org/10.1007/978-3-319-09414-4_6

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