Skip to main content

Pulmonary Hypertension

  • Chapter
  • First Online:
  • 2809 Accesses

Abstract

Pulmonary hypertension (PH) confers increased risk of perioperative morbidity and mortality for patients undergoing noncardiac surgery. Surgery in patients with PH can result in hypoxia, hypercapnia, and volume shifts exacerbating the underlying pulmonary hypertension, leading to acute right ventricular failure. Pathophysiologic effects may quickly spiral out of control as pulmonary pressures rise, causing worsening cardiac output, systemic hypotension, cardiac ischemia, and ultimately death.

Management of patients with pulmonary hypertension undergoing cardiac surgery is a complex subject outside the scope of this chapter. Consultation with a cardiac anesthesiologist is recommended in such cases.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Ramakrishna G, Sprung J, Ravi BS, et al. Impact of pulmonary hypertension on the outcomes of noncardiac surgery: predictors of perioperative morbidity and mortality. J Am Coll Cardiol. 2005;45(10):1691–9.

    Article  PubMed  Google Scholar 

  2. Kaw R, Sharma P, Minai OA. What risks does a history of pulmonary hypertension present for patients undergoing noncardiac surgery? Cleve Clin J Med. 2007;74 Suppl 1:S20–1.

    Article  PubMed  Google Scholar 

  3. Lai HC, Lai HC, Wang KY, et al. Severe pulmonary hypertension complicates postoperative outcome of non-cardiac surgery. Br J Anaesth. 2007;99(2):184–90.

    Article  PubMed  Google Scholar 

  4. Memtsoudis SG, Ma T, Chiu YL, et al. Perioperative mortality in patients with pulmonary hypertension undergoing major joint replacement. Anesth Analg. 2010;111(5):1110–6.

    Article  PubMed  Google Scholar 

  5. Kaw R, Pasupuleti V, Deshpande A, et al. Pulmonary hypertension: an important predictor of outcomes in patients undergoing non-cardiac surgery. Respir Med. 2011;105(4):619–24.

    Article  PubMed  Google Scholar 

  6. Minai OA, Yared J, Kaw R, et al. Perioperative risk and management in patients with pulmonary hypertension. Chest. 2013;144(1):329–40.

    Article  PubMed  Google Scholar 

  7. Fleisher LA, Beckman JA, Brown KA, et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2007;116:e418–500.

    Article  PubMed  Google Scholar 

  8. McLaughlin VV, Archer SL, Badesch DB, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension. J Am Coll Cardiol. 2009;53:1573–619.

    Article  PubMed  Google Scholar 

  9. Poirier P, Alpert MA, Fleisher LA, et al. Cardiovascular evaluation and management of severely obese patients undergoing surgery: a science advisory from the American Heart Association. Circulation. 2009;120:86–95.

    Article  PubMed  Google Scholar 

  10. McLaughlin VV, McGoon MD. Pulmonary arterial hypertension. Circulation. 2006;114(13):1417–31.

    Article  PubMed  Google Scholar 

  11. Simonneau G, Galiè N, Rubin L, et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2004;43:5–12.

    Article  Google Scholar 

  12. Krowka MJ, Plevak DJ, Findlay JY, et al. Pulmonary hemodynamics and perioperative cardiopulmonary-related mortality in patients with portopulmonary hypertension undergoing liver transplantation. Liver Transpl. 2000;6(4):443–50.

    Article  CAS  PubMed  Google Scholar 

  13. Price LC, Montani D, Jaïs X, et al. Noncardiothoracic nonobstetric surgery in mild-to-moderate pulmonary hypertension. Eur Respir J. 2010;35(6):1294–302.

    Article  CAS  PubMed  Google Scholar 

  14. Humbert M, Sitbon OS, Simmoneau G. Treatment of pulmonary arterial hypertension. N Engl J Med. 2004;351:1425–36.

    Article  CAS  PubMed  Google Scholar 

  15. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002; 166(1):111–7.

    Article  Google Scholar 

  16. Collisson EA, Nourmand H, Fraiman MH, et al. Retrospective analysis of the results of liver transplantation for adults with severe hepatopulmonary syndrome. Liver Transpl. 2002; 8(10):925–31.

    Article  PubMed  Google Scholar 

  17. Jones AM, Howitt G. Eisenmenger syndrome in pregnancy. Br Med J. 1965;1(5451):1627–31.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Rodriguez R, Pearl RG. Pulmonary hypertension and major surgery. Anesth Analg. 1998;87(4):812–5.

    CAS  PubMed  Google Scholar 

  19. Minai O, Budev MM. Treating pulmonary arterial hypertension: cautious hope in a deadly disease. Cleve Clin J Med. 2007;74(11):789–806.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Brian S. Porter M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Porter, B.S. (2015). Pulmonary Hypertension. In: Jackson, M.B., Mookherjee, S., Hamlin, N.P. (eds) The Perioperative Medicine Consult Handbook. Springer, Cham. https://doi.org/10.1007/978-3-319-09366-6_30

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-09366-6_30

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-09365-9

  • Online ISBN: 978-3-319-09366-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics