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Transfusion Therapy and Massive Transfusions

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Hemostasis and Thrombosis

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Abstract

This chapter will discuss the key blood products in bleeding patients—platelets, fresh frozen plasma, and cryoprecipitate. Management of massive transfusions will also be covered. Many patients with bleeding disorders will require transfusion of blood products. This chapter will summarize the use of blood products for hemostasis. This chapter will also discuss the art of managing a massive transfusion.

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Suggested Reading

  • Anonymous. Leukocyte reduction and ultraviolet B irradiation of platelets to prevent alloimmunization and refractoriness to platelet transfusions. The Trial to Reduce Alloimmunization to Platelets Study Group. N Engl J Med. 1997; 337(26):1861-9.

    Google Scholar 

  • DeLoughery TG. Logistics of massive transfusions. Hematology Am Soc Hematol Educ Program. 2010;2010:470–3.

    Article  PubMed  Google Scholar 

  • GmĂĽr J, Burger J, Schanz U, Fehr J, Schaffner A. Safety of stringent prophylactic platelet transfusion policy for patients with acute leukaemia. Lancet. 1991;338(8777):1223–6.

    Article  PubMed  Google Scholar 

  • Hallet J, Lauzier F, Mailloux O, Trottier V, Archambault P, Zarychanski R, Turgeon AF. The use of higher platelet: RBC transfusion ratio in the acute phase of trauma resuscitation: a systematic review. Crit Care Med. 2013;41(12):2800–11.

    Article  PubMed  Google Scholar 

  • Rebulla P. A mini-review on platelet refractoriness. Haematologica. 2005;90(2):247–53.

    PubMed  Google Scholar 

  • Slichter SJ. Evidence-based platelet transfusion guidelines. Hematology Am Soc Hematol Educ Program. 2007:172–8

    Google Scholar 

  • Yang L, Stanworth S, Hopewell S, Doree C, Murphy M. Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials. Transfusion. 2012;52(8):1673–86.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Pathology and Pediatrics, Oregon Health and Science University, Portland, OR, 97239, USA

    Thomas G. DeLoughery M.D., F.A.C.P., F.A.W.M. (Professor of Medicine)

Authors
  1. Thomas G. DeLoughery M.D., F.A.C.P., F.A.W.M.
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Correspondence to Thomas G. DeLoughery M.D., F.A.C.P., F.A.W.M. .

Editor information

Editors and Affiliations

  1. Medicine, Pathology, and Pediatrics, Oregon Health & Science University, Portland, Oregon, USA

    Thomas G. DeLoughery

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© 2015 Springer International Publishing Switzerland

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DeLoughery, T.G. (2015). Transfusion Therapy and Massive Transfusions. In: DeLoughery, T. (eds) Hemostasis and Thrombosis. Springer, Cham. https://doi.org/10.1007/978-3-319-09312-3_14

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  • DOI: https://doi.org/10.1007/978-3-319-09312-3_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-09311-6

  • Online ISBN: 978-3-319-09312-3

  • eBook Packages: MedicineMedicine (R0)

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