Abstract
Basal cell adenoma is the benign counterpart of basal cell adenocarcinoma. Basal cell adenoma affects primarily adults and presents at a mean age of approximately 65 years. Women are involved slightly more than men. The majority of cases involve the parotid gland, presenting as single or multiple masses. Basal cell adenoma may be well-circumscribed or multinodular, comprised of multiple cell types (ductal and basal), and exhibit a variety of architectural patterns (solid, trabecular, tubular, and membranous) (Figs. 8.1, 8.2, 8.3, 8.4, 8.5, 8.6, 8.7, 8.8, 8.9, 8.10, 8.11, 8.12, 8.13, 8.14, 8.15, 8.16, 8.17, 8.18, 8.17, 8.18, 8.18, 8.19, 8.20, 8.21, 8.22, 8.23, 8.24, 8.24, 8.25, 8.26, 8.27 and 8.28).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Bastakis JG, Luna MA, el-Naggar AK. Basaloid monorphic adenomas. Ann Otol Rhinol Laryngol. 1991;100:687–90.
Chhieng DC, Paulino AF. Basaloid tumors of the salivary glands. Ann Diagn Pathol. 2002;6(6):364–72.
Edwards PC, Bhuiya T, Kelsch RD. Assessment of p63 expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and basal cell and canalicular adenomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97(5):613–9.
Ethunandan M, Pratt CA, Macpherson DW. Changing frequency of parotid gland neoplasms—analysis of 560 tumors treated in a district general hospital. Ann R Coll Surg Engl. 2002;84:1–6.
Hyman BA, Scheithauer BW, Weiland LH, Irons GB. Membranous basal cell adenoma of the parotid gland. Malignant transformation in a patient with multiple dermal cylindromas. Arch Pathol Lab Med. 1988;112:209–11.
Klijanienko J, El-Naggar AK, Vielh P. Comparative cytologic and histologic study of fifteen salivary basal-cell tumors: differential diagnostic considerations. Diagn Cytopathol. 1999;21(1):30–4.
Machado de Sousa SO, Soares de Araújo N, Corrêa L, Pires Soubhia AM, Cavalcanti de Araújo V. Immunohistochemical aspects of basal cell adenoma and canalicular adenoma of salivary glands. Oral Oncol. 2001;37(4):365–8.
Nagao T, Sugano I, Ishida Y, Hasegawa M, Matsuzaki O, Konno A, et al. Basal cell adenocarcinoma of the salivary glands: comparison with basal cell adenoma through assessment of cell proliferation, apoptosis, and expression of p53 and bcl-2. Cancer. 1998;82(3):439–47.
Scott AR, Faquin WC, Deschler DG. Parotid mass in a woman with multiple cutaneous cylindromas. Head Neck. 2010;32:684–7.
Tian Z, Li L, Wang L, Hu Y, Li J. Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 case in an eastern Chinese population. Int J Oral Maxillofac Surg. 2010;39:235–42.
Wilson TC, Robinson RA. Basal cell adenocarcinoma and basal cell adenoma of the salivary glands: a clinicopathological review of seventy tumors with comparison of morphologic features and growth control indices. Head Neck Pathol. 2015;9:205–13.
Yu GY, Ubmüller J, Donath K. Membranous basal cell adenoma of the salivary gland: a clinicopathologic study of 12 cases. Acta Otolaryngol. 1998;118:588–93.
Zarbo RJ, Prasad AR, Regezi JA, Gown AM, Savera AT. Salivary gland basal cell and canalicular adenomas: immunohistochemical demonstration of myoepithelial cell participation and morphogenetic considerations. Arch Pathol Lab Med. 2000;124(3):401–5.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
García, J.J. (2019). Basal Cell Adenoma. In: Atlas of Salivary Gland Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-09021-4_8
Download citation
DOI: https://doi.org/10.1007/978-3-319-09021-4_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-09020-7
Online ISBN: 978-3-319-09021-4
eBook Packages: MedicineMedicine (R0)