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Laboratory Hemostasis pp 117–134Cite as

Testing for Inherited and Acquired Thrombotic Disorders

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Abstract

Virchow’s triad, the major risk factors that predispose to thrombosis, include vascular injury, stasis, and hypercoagulability. Arterial and venous thrombosis have different pathogenic mechanisms. For example, arterial thrombosis primarily involves vascular injury (atherosclerosis) and platelet deposition. Venous thrombosis primarily involves stasis of blood flow and hypercoagulability, which is defined as altered blood composition associated with a thrombotic tendency. Fibrin deposition is the normal consequence of venous thrombosis.

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Authors and Affiliations

  1. Division of Hematology, University of Utah Health Sciences Center, Salt Lake City, UT, USA

    George M. Rodgers MD, PhD

  2. Coagulation Laboratory, ARUP Laboratories, Salt Lake City, UT, USA

    George M. Rodgers MD, PhD

Authors
  1. George M. Rodgers MD, PhD
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Correspondence to George M. Rodgers MD, PhD .

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© 2015 Springer International Publishing Switzerland

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Rodgers, G.M. (2015). Testing for Inherited and Acquired Thrombotic Disorders. In: Laboratory Hemostasis. Springer, Cham. https://doi.org/10.1007/978-3-319-08924-9_9

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  • DOI: https://doi.org/10.1007/978-3-319-08924-9_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-08923-2

  • Online ISBN: 978-3-319-08924-9

  • eBook Packages: MedicineMedicine (R0)

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