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Management of Overt Diabetic Kidney Disease and Uremia

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Managing Diabetic Nephropathies in Clinical Practice

Abstract

Once long-standing diabetes has involved the kidneys, the process of ongoing damage to predominantly glomerular structures cannot be stopped by currently available therapeutic interventions. Kidney damage is considered to be clinically “silent” (lacking obvious symptoms) and may present in two forms. Most commonly, proteinuria, starting as microalbuminuria, is the leading presentation. However, in approximately one in every seven patients, a reduction in estimated glomerular filtration (eGFR), without any type of albuminuria, is the first sign of kidney involvement in diabetes [1].

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Schernthaner, G., Prischl, F.C. (2017). Management of Overt Diabetic Kidney Disease and Uremia. In: Managing Diabetic Nephropathies in Clinical Practice. Adis, Cham. https://doi.org/10.1007/978-3-319-08873-0_5

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