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Stochastic Ion Channels

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Stochastic Processes in Cell Biology

Part of the book series: Interdisciplinary Applied Mathematics ((IAM,volume 41))

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Abstract

Ion channels are pore-forming membrane proteins that gate the flow of ions across the cell membrane and the membrane of various intracellular organelles [261, 322]. More than 300 different types of ion channels have been identified across different cell types, which are primarily classified by the nature of their gating and the species of ions passing through the open gates. For example, the opening and closing of voltage-gated ion channels depends on the voltage gradient across the plasma membrane, while ligand-gated ion channels are open or closed by the binding of ligands to the channel. Both types are particularly prominent components of the nervous system, where voltage-gated ion channels underlie the generation of action potentials and ligand-gated (neurotransmitter activated) ion channels mediate conduction across synapses.

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  1. Department of Mathematics, University of Utah, Salt Lake City, UT, USA

    Paul C. Bressloff

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Bressloff, P.C. (2014). Stochastic Ion Channels. In: Stochastic Processes in Cell Biology. Interdisciplinary Applied Mathematics, vol 41. Springer, Cham. https://doi.org/10.1007/978-3-319-08488-6_3

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