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Neurofilaments Transport in Axon

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Mathematical Modeling of Biological Processes

Abstract

Most axonal proteins are synthesized in the nerve cell body and are then transported along the axon. One type of cargo structures is neurofilaments, neuron-specific cytoskeleton polymers that function as space-filling structure in axon. Each such cargo is attached to a motor protein that travels along microtubules. This piggybacking transport is illustrated in Fig. 9.1.

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Bibliography

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Friedman, A., Kao, CY. (2014). Neurofilaments Transport in Axon. In: Mathematical Modeling of Biological Processes. Lecture Notes on Mathematical Modelling in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-319-08314-8_9

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