Skip to main content
SpringerLink
Log in

Screening and prevention of ovarian cancer

  • Chapter
  • First Online:
The 21st Century Handbook of Clinical Ovarian Cancer

Abstract

Use of oral contraceptive pills (OCPs) has been associated with a significant reduction in the risk of ovarian cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Centers for Disease Control and Prevention and the National Institute of Child Health and Human Development. The reduction in risk of ovarian cancer associated with oral‑contraceptive use. The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development. N Engl J Med. 1987;316:650-655.

    Google Scholar 

  2. Schildkraut JM, Calingaert B, Marchbanks PA, Moorman PG, Rodriguez GC. Impact of progestin and estrogen potency in oral contraceptives on ovarian cancer risk. J Natl Cancer Inst. 2002;94:32-38.

    Google Scholar 

  3. Greer JB, Modugno F, Allen GO, Ness RB. Androgenic progestins in oral contraceptives and the risk of epithelial ovarian cancer. Obstet Gynecol. 2005;105:731-740.

    Google Scholar 

  4. Berek JS, Chalas E, Edelson M, et al. Prophylactic and risk-reducing bilateral salpingo‑oophorectomy: recommendations based on risk of ovarian cancer. Obstet Gynecol. 2010;116:733-743.

    Google Scholar 

  5. Kurman RJ, Shih Ie-Ming. The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. Am J Surg Pathol. 2010;34:433-443.

    Google Scholar 

  6. Finch A, Beiner M, Lubinski J, et al. Salpingo-oophorectomy and the risk of ovarian fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 mutation. JAMA. 2006;296:185-192.

    Google Scholar 

  7. Welsch PL, King MC. BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum Mol Genet. 2001;10:705-713.

    Google Scholar 

  8. Green MH, Piedmonte M, Alberts D, et al. A prospective study of risk-reducing salpingooophorectomy and longitudinal CA-125 screening among women at increased genetic risk of ovarian cancer: design and baseline characteristics: a Gynecologic Oncology Group study. Cancer Epidemiol Biomarkers Prev. 2008;17:594-604.

    Google Scholar 

  9. Mai PL, Sherman ME, Piedmonte M, et al. Pathologic findings at risk-reducing salpingooophorectomy among women at increased ovarian cancer risk: results from GOG-199. J Clin Oncol. 2012;30 (abstr 1519).

    Google Scholar 

  10. Bast RC Jr, Klug TL, St John E, et al. A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. N Engl J Med. 1983;309:883-887.

    Google Scholar 

  11. Cramer DW, Bast RC Jr, Berg CD, et al. Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens. Cancer Prev Res (Phila). 2011;4:365‑374.

    Google Scholar 

  12. Buys SS, Partridge E, Black A, et al. Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial. JAMA. 2011;305:2295-2303.

    Google Scholar 

  13. Moore LE, Pfeiffer RM, Zhang Z, et al. Proteomic biomarkers in combination with CA 125 for detection of epithelial ovarian cancer using prediagnostic serum samples from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. Cancer. 2012;118:91-100.

    Google Scholar 

  14. Partridge E, Kreimer AR, Greenlee RT, et al. Results from four rounds of ovarian cancer screening in a randomized trial. Obstet Gynecol. 2009;113:775-782.

    Google Scholar 

  15. McIntosh MW et al. Generating longitudinal screening algorithms using novel biomarkers for disease. Cancer Epidemiol Biomarkers Prev. 2002;11:159-166.

    Google Scholar 

  16. Lu KH, Skates S, Hernandez MA, et al. A 2-stage ovarian cancer screening strategy using the Risk of Ovarian Cancer Algorithm (ROCA) identifies early-stage incident cancers and demonstrates high positive predictive value. Cancer. 2013;119:3454-3461.

    Google Scholar 

  17. Menon U, Gentry-Maharaj A, Hallett R, et al. Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Lancet Oncol. 2009;10:327-340.

    Google Scholar 

  18. Rosenthal AN, Fraser L, Manchanda R, et al. Results of annual screening in phase I of the United Kingdom familial ovarian cancer screening study highlight the need for strict adherence to screening schedule. J Clin Oncol. 2013;31:49-57.

    Google Scholar 

  19. Rosenthal N, Fraser L, Philpott S, et al. Final results of 4-monthly screening in the UK Familial Ovarian Cancer Screening Study (UKFOCSS Phase 2). J Clin Oncol. 2013;31(suppl;abstr 5507).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University of California, Irvine Medical Gynecologic Oncology Group, Orange, California, USA

    Krishnansu Tewari

  2. St Joseph’s Hospital and Medical Center Division of Gynecologic Oncology, Phoenix, Arizona, USA

    Bradley Monk

Authors
  1. Krishnansu Tewari
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bradley Monk
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Tewari, K., Monk, B. (2015). Screening and prevention of ovarian cancer. In: The 21st Century Handbook of Clinical Ovarian Cancer. Adis, Cham. https://doi.org/10.1007/978-3-319-08066-6_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-08066-6_2

  • Published:

  • Publisher Name: Adis, Cham

  • Print ISBN: 978-3-319-08065-9

  • Online ISBN: 978-3-319-08066-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation