Abstract
Goals Total mesorectal excision (TME) is the gold standard technique for the surgical treatment of rectal cancer. Despite the benefits of minimally invasive surgery, laparoscopic TME (LTME) is a technically challenging procedure with a long learning curve. Robotic TME (RTME) has been advocated as an alternative to conventional LTME, but large studies supporting the efficacy or RTME are scarce. This work will review the current literature on minimally invasive surgery for rectal cancer and discuss future directions in the field. Methods A review of recent large single and multicenter studies on minimally invasive surgery for rectal cancer was conducted. Results Based on two large randomized clinical studies (CLASICC (Green et al. 2013) and COLOR II (van der Pas et al. 2013)). LTME is safe and feasible for the treatment of rectal cancer. Compared to open surgery, LTME has been shown to result in superior postoperative outcomes and similar oncologic results. However, the conversion rate of LTME is around 17 %. The literature supporting RTME is more limited. Robotic rectal resection appears to have similar postoperative and oncologic outcomes compared to LTME. RTME results in higher costs and possibly lower conversion rates. A large randomized clinical trial (ROLARR) comparing robotic to laparoscopic surgery for rectal cancer is underway. Conclusions Despite the technical challenges, current data supports the use of minimally invasive technique for rectal cancer surgery with superior short-term outcomes compared to an open approach. The use of robotic surgery is promising, but still limited and awaiting the conclusion of randomized clinical trials.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Aitken RJ (1996) Mesorectal excision for rectal cancer. Br J Surg 83(2):214–216
Anderson C, Uman G, Pigazzi A (2008) Oncologic outcomes of laparoscopic surgery for rectal cancer: a systematic review and meta-analysis of the literature. European J Surg Oncol: J Eur Soc Surg Oncol Br Assoc Surg Oncol 34(10):1135–1142
Atallah S, Martin-Perez B, Albert M et al (2013a) Transanal minimally invasive surgery for total mesorectal excision (TAMIS-TME): results and experience with the first 20 patients undergoing curative-intent rectal cancer surgery at a single institution. Tech Coloproctol
Atallah S, Albert M, DeBeche-Adams T, Nassif G, Polavarapu H, Larach S (2013b) Transanal minimally invasive surgery for total mesorectal excision (TAMIS-TME): a stepwise description of the surgical technique with video demonstration. Tech Coloproctol 17(3):321–325
Baek SJ, Al-Asari S, Jeong DH et al (2013a) Robotic versus laparoscopic coloanal anastomosis with or without intersphincteric resection for rectal cancer. Surg Endosc
Baek SK, Carmichael JC, Pigazzi A (2013b) Robotic surgery: colon and rectum. Cancer J 19(2):140–146
Baik SH, Kwon HY, Kim JS et al (2009) Robotic versus laparoscopic low anterior resection of rectal cancer: short-term outcome of a prospective comparative study. Ann Surg Oncol 16(6):1480–1487
Beck DE, Steven D (1998) Fundamentals of anorectal surgery, 2nd edn. WB Saunders, London
Biffi R, Luca F, Pozzi S et al (2011) Operative blood loss and use of blood products after full robotic and conventional low anterior resection with total mesorectal excision for treatment of rectal cancer. J Robot Surg 5(2):101–107
Bissett IP, Hill GL (2000) Extrafascial excision of the rectum for cancer: a technique for the avoidance of the complications of rectal mobilization. Semin Surg Oncol 18(3):207–215
Breukink S, Pierie J, Wiggers T (2006) Laparoscopic versus open total mesorectal excision for rectal cancer. Cochrane Database Syst Rev 2006(4):CD005200
Chapuis P, Bokey L, Fahrer M, Sinclair G, Bogduk N (2002) Mobilization of the rectum: anatomic concepts and the bookshelf revisited. Dis Colon Rectum 45(1):1–8 (discussion 8–9)
Colon Cancer Laparoscopic or Open Resection Study Group, Buunen M, Veldkamp R et al (2009) Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol 10(1):44–52
D’Annibale A, Pernazza G, Monsellato I et al (2013) Total mesorectal excision: a comparison of oncological and functional outcomes between robotic and laparoscopic surgery for rectal cancer. Surg Endosc 27(6):1887–1895
Du XH, Shen D, Li R et al (2013) Robotic anterior resection of rectal cancer: technique and early outcome. Chin Med J 126(1):51–54
Enker WE, Thaler HT, Cranor ML, Polyak T (1995) Total mesorectal excision in the operative treatment of carcinoma of the rectum. J Am Coll Surg 181(4):335–346
Fleshman J, Sargent DJ, Green E et al (2007) Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group trial. Ann of Surg 246(4):655–662 (discussion 662–654)
Goligher JC (1960) Colon, rectum, and anus—surgical. Med Annu 78:40–53
Green BL, Marshall HC, Collinson F et al (2013) Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 100(1):75–82
Halabi WJ, Kang CY, Jafari MD et al (2013) Robotic-assisted colorectal surgery in the United States: a nationwide analysis of trends and outcomes. World J Surg 37(12):2782–2790
Heald RJ (1979) A new approach to rectal cancer. Br J Hosp Med 22(3):277–281
Heald RJ, Moran BJ, Ryall RD, Sexton R, MacFarlane JK (1998) Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978–1997. Arch Surg 133(8):894–899
Jayne DG, Guillou PJ, Thorpe H et al (2007) Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol: Off J Am Soc Clin Oncol 25(21):3061–3068
Kapiteijn E, Putter H, van de Velde CJ, Cooperative Investigators of the Dutch ColoRectal Cancer Group (2002) Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in the Netherlands. Br J Surg 89(9):1142–1149
Kapiteijn E, Marijnen CA, Nagtegaal ID et al (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345(9):638–646
Killingback M, Barron P, Dent OF (2001) Local recurrence after curative resection of cancer of the rectum without total mesorectal excision. Dis Colon Rectum 44(4):473–483 (discussion 483–476)
Kim CW, Kim CH, Baik SH (2014) Outcomes of robotic-assisted colorectal surgery compared with laparoscopic and open surgery: a systematic review. J Gastrointest Surg: Off J Soc Surg Aliment Tract
Law WL, Chu KW (2004) Anterior resection for rectal cancer with mesorectal excision: a prospective evaluation of 622 patients. Ann Surg 240(2):260–268
Leung KL, Kwok SP, Lam SC et al (2004) Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial. Lancet 363(9416):1187–1192
Luca F, Valvo M, Ghezzi TL et al (2013) Impact of robotic surgery on sexual and urinary functions after fully robotic nerve-sparing total mesorectal excision for rectal cancer. Ann Surg 257(4):672–678
Memon S, Heriot AG, Murphy DG, Bressel M, Lynch AC (2012) Robotic versus laparoscopic proctectomy for rectal cancer: a meta-analysis. Ann Surg Oncol 19(7):2095–2101
Morino M, Parini U, Giraudo G, Salval M, Brachet Contul R, Garrone C (2003) Laparoscopic total mesorectal excision: a consecutive series of 100 patients. Ann Surg 237(3):335–342
Pasupathy S, Eu KW, Ho YH, Seow-Choen F (2001) A comparison between open versus laparoscopic assisted colonic pouches for rectal cancer. Tech Coloproctol 5(1):19–22
Pigazzi A, Ellenhorn JD, Ballantyne GH, Paz IB (2006) Robotic-assisted laparoscopic low anterior resection with total mesorectal excision for rectal cancer. Surg Endosc 20(10):1521–1525
Qu C, Yuan RF, Huang J et al (2013) [Meta-analysis of laparoscopic versus open total mesorectal excision for middle and low rectal cancer]. Zhonghua wei chang wai ke za zhi = Chin J Gastrointest Surg 16(8):748–752
Sauer R, Fietkau R, Wittekind C et al (2001) Adjuvant versus neoadjuvant radiochemotherapy for locally advanced rectal cancer. A progress report of a phase-III randomized trial (protocol CAO/ARO/AIO-94). Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft … [et al] 177(4):173–181
Sauer R, Fietkau R, Wittekind C et al (2003) Adjuvant vs. neoadjuvant radiochemotherapy for locally advanced rectal cancer: the German trial CAO/ARO/AIO-94. Colorectal Dis: Off J Assoc Coloproctol G B Irel 5(5):406–415
Scheidbach H, Schneider C, Konradt J et al (2002) Laparoscopic abdominoperineal resection and anterior resection with curative intent for carcinoma of the rectum. Surg Endosc 16(1):7–13
Stewart DB, Dietz DW (2007) Total mesorectal excision: what are we doing? Clin Colon Rectal Surg 20(3):190–202
Tiret E, Pocard M (1999) Total excision of the mesorectum and preservation of the genitourinary innervation in surgery of rectal cancer. Ann Chir 53(6):507–514
Trastulli S, Farinella E, Cirocchi R et al (2012) Robotic resection compared with laparoscopic rectal resection for cancer: systematic review and meta-analysis of short-term outcome. Colorectal Dis: Off J Assoc Coloproctol G B Irel 14(4):e134–e156
van der Pas MH, Haglind E, Cuesta MA et al (2013) Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol 14(3):210–218
Veldkamp R, Kuhry E, Hop WC et al (2005) Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol 6(7):477–484
Yu J, Zhang C, Wang YN, Hu YF, Cheng X, Li GX (2009) [Laparoscopic versus open total mesorectal excision for the middle-lower rectal cancer: a clinical comparative study]. Zhonghua wei chang wai ke za zhi = Chin J Gastrointest Surg 12(6):573–576
Zhou ZG, Hu M, Li Y et al (2004) Laparoscopic versus open total mesorectal excision with anal sphincter preservation for low rectal cancer. Surg Endosc 18(8):1211–1215
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Young, M., Pigazzi, A. (2014). Total Mesorectal Excision: Open, Laparoscopic or Robotic. In: Otto, F., Lutz, M. (eds) Early Gastrointestinal Cancers II: Rectal Cancer. Recent Results in Cancer Research, vol 203. Springer, Cham. https://doi.org/10.1007/978-3-319-08060-4_6
Download citation
DOI: https://doi.org/10.1007/978-3-319-08060-4_6
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-08059-8
Online ISBN: 978-3-319-08060-4
eBook Packages: MedicineMedicine (R0)