The Beginnings of Molecular Biology

  • Milton W. TaylorEmail author


This chapter describes the beginnings of molecular biology with the discovery of bacterial transformation and identification of DNA as the genetic material. The role that bacteriophage and the Cold Spring Harbor Phage group played in this development are emphasized. The discovery of transducing phage and the regulation of gene expression in the temperate phage lambda led to models of transcriptional and translational control. The discovery of lysogeny, and the integration of the bacteriophage into the host chromosome, ultimately led to the idea of cancer viruses being integrated into the chromosome and the oncogene model of cancer.


Cold Spring Harbor Mouse Mammary Tumor Virus Phage Particle Phage Genome Bacterial Chromosome 
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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  1. 1.Indiana UniversityBloomingtonUSA

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