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Normal Anatomy of the Peripheral (Sural) Nerve

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Biopsy Diagnosis of Peripheral Neuropathy

Abstract

In this chapter, we review the peripheral nerve anatomy pertinent to interpretation of biopsy material. We discuss the epineurial, perineurial, and endoneurial compartments of nerve, followed by a description of the changes that occur with aging. In subsequent chapters, we will deal with the ultrastructure and pathophysiology of axons, Schwann cells and myelin, the neural vasculature, as well as aspects of quantitative morphometry. Because the sural nerve is almost universally the nerve chosen for biopsy, certain elements of the discussion are specific to this site.

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Authors and Affiliations

  1. Sunnybrook and St Michael’s Hospitals, University of Toronto, Toronto, ON, Canada

    Juan M. Bilbao MD, FRCP (C) (Professor Emeritus of Neuropathology)

  2. Division of Neuropathology Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA

    Robert E. Schmidt MD, PhD (Professor of Pathology and Immunology Director)

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  1. Juan M. Bilbao MD, FRCP (C)
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  2. Robert E. Schmidt MD, PhD
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Bilbao, J.M., Schmidt, R.E. (2015). Normal Anatomy of the Peripheral (Sural) Nerve. In: Biopsy Diagnosis of Peripheral Neuropathy. Springer, Cham. https://doi.org/10.1007/978-3-319-07311-8_2

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  • DOI: https://doi.org/10.1007/978-3-319-07311-8_2

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