Abstract
Intraoperative bacterial contamination of the surgical wound is a major source of postoperative prosthetic joint infection. In order to reduce intraoperative bacterial contamination of the wound and surgical site infections, several strategies have been developed, tested, and implemented. These strategies include those which address specific operating room variables (operating room ventilation), surgical factors (draping materials, irrigation, wound closure, etc.), patient factors, and factors controlled by the surgical team (hand cleansing, use of face masks, etc.). This chapter will discuss the different causes of bacterial contamination in the operating room, the approaches to reduce them, and their effect in diminishing the rates of infection. The collective use of the factors discussed in the chapter will result in a substantial reduction in the rate of acute postoperative infection.
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References
Abolghasemian M et al (2013) Is arthroplasty immediately after an infected case a risk factor for infection? Clin Orthop Relat Res 471(7):2253–2258
Aglietti P et al (1974) Effect of a surgical horizontal unidirectional filtered air flow unit on wound bacterial contamination and wound healing. Clin Orthop Relat Res 101:99–104
Al-Maiyah M et al (2005) Glove perforation and contamination in primary total hip arthroplasty. J Bone Joint Surg Br 87(4):556–559
Andersson BM et al (1984) Contamination of irrigation solutions in an operating theatre. Infect Control 5(7):339–341
Anglen JO et al (2003) The use of detergent irrigation for musculoskeletal wounds. Int Orthop 27(1):40–46
Anon (2011) Fluid lavage of open wounds (FLOW): a multicenter, blinded, factorial pilot trial comparing alternative irrigating solutions and pressures in patients with open fractures. J Trauma 71(3):596–606
Antevil JL et al (2003) Intraoperative anaphylactic shock associated with bacitracin irrigation during revision total knee arthroplasty. A case report. J Bone Joint Surg Am 85-A(2):339–342
Anto B et al (2006) Splash basin bacterial contamination during elective arthroplasty. J Infect 52(3):231–232
AORN Recommended Practices Committee (2006) Recommended practices for maintaining a sterile field. AORN J 83(2):402–404, 407–410, 413–416
Association of periOperative Registered Nurses Recommended Practices Committee (2004) Recommended practices for surgical hand antisepsis/hand scrubs. AORN J 79(2):416–418, 421–416, 429–431
Baird RA et al (1984) Splash basin contamination in orthopaedic surgery. Clin Orthop Relat Res 187:129–133
Barrack RL et al (2012) Patient specific cutting blocks are currently of no proven value. J Bone Joint Surg Br 94(11 Suppl A):95–99
Bellchambers J et al (1999) A prospective study of wound infection in coronary artery surgery. Eur J Cardiothorac Surg 15(1):45–50
Bennett RG, Kraffert CA (1990) Bacterial transference during electrodesiccation and electrocoagulation. Arch Dermatol 126(6):751–755
Berg M, Bergman BR, Hoborn J (1989) Shortwave ultraviolet radiation in operating rooms. J Bone Joint Surg Br 71(3):483–485
Berg M, Bergman BR, Hoborn J (1991) Ultraviolet radiation compared to an ultra-clean air enclosure. Comparison of air bacteria counts in operating rooms. J Bone Joint Surg Br 73(5):811–815
Bible JE et al (2009) Which regions of the operating gown should be considered most sterile? Clin Orthop Relat Res 467(3):825–830
Blom A et al (2000) The passage of bacteria through surgical drapes. Ann R Coll Surg Engl 82(6):405–407
Blom AW et al (2002) Bacterial strike-through of re-usable surgical drapes: the effect of different wetting agents. J Hosp Infect 52(1):52–55
Blom AW et al (2007) Resistance of disposable drapes to bacterial penetration. J Orthop Surg (Hong Kong) 15(3):267–269
Brady RRW et al (2012) NHS connecting for health: healthcare professionals, mobile technology, and infection control. Telemed J E Health 18(4):289–291
Bratzler DW et al (2013) Clinical practice guidelines for antimicrobial prophylaxis in surgery. Surg Infect (Larchmt) 14(1):73–156
Breier A-C et al (2011) Laminar airflow ceiling size: no impact on infection rates following hip and knee prosthesis. Infect Control Hosp Epidemiol 32(11):1097–1102
Brown LL et al (1978) Evaluation of wound irrigation by pulsatile jet and conventional methods. Ann Surg 187(2):170–173
Brown AR, Taylor GJ, Gregg PJ (1996) Air contamination during skin preparation and draping in joint replacement surgery. J Bone Joint Surg Br 78(1):92–94
Carlsson AS et al (1986) Ultraviolet radiation and air contamination during total hip replacement. J Hosp Infect 7(2):176–184
Carroll K et al (2014) Risk factors for superficial wound complications in hip and knee arthroplasty. Clin Microbiol Infect 20(2):130–135
Carter AH et al (2012) A prospective analysis of glove perforation in primary and revision total hip and total knee arthroplasty. J Arthroplasty 27(7):1271–1275
Cervantes-Sánchez CR et al (2000) Syringe pressure irrigation of subdermic tissue after appendectomy to decrease the incidence of postoperative wound infection. World J Surg 24(1):38–41; discussion 41–42
Charnley J (1972) Postoperative infection after total hip replacement with special reference to air contamination in the operating room. Clin Orthop Relat Res 87:167–187
Charnley J, Eftekhar N (1969) Postoperative infection in total prosthetic replacement arthroplasty of the hip-joint. With special reference to the bacterial content of the air of the operating room. Br J Surg 56(9):641–649
Chen ZY Gao Y, Chen W, Li X, Zhang YZ (2013) Is wound drainage necessary in hip arthroplasty? A meta-analysis of randomized controlled trials. Eur J Orthop Surg Traumatol (Epub ahead of print)
Chiu KY et al (1993) Plastic adhesive drapes and wound infection after hip fracture surgery. Aust N Z J Surg 63(10):798–801
Chosky SA, Modha D, Taylor GJ (1996) Optimisation of ultraclean air. The role of instrument preparation. J Bone Joint Surg Br 78(5):835–837
Chundamala J, Wright JG (2007) The efficacy and risks of using povidone-iodine irrigation to prevent surgical site infection: an evidence-based review. Can J Surg 50(6):473–481
Conroy BP et al (1999) Comparison of castile soap, benzalkonium chloride, and bacitracin as irrigation solutions for complex contaminated orthopaedic wounds. J Orthop Trauma 13(5):332–337
Cordero-Ampuero J, de Dios M (2010) What are the risk factors for infection in hemiarthroplasties and total hip arthroplasties? Clin Orthop Relat Res 468(12):3268–3277
Dalstrom DJ et al (2008) Time-dependent contamination of opened sterile operating-room trays. J Bone Joint Surg Am 90(5):1022–1025
Davis N et al (1999) Intraoperative bacterial contamination in operations for joint replacement. J Bone Joint Surg Br 81(5):886–889
de Boer AS et al (2001) Risk assessment for surgical site infections following total hip and total knee prostheses. J Chemother (Florence, Italy) 13 Spec No 1(1):42–47
Demircay E et al (2010) Glove perforation in hip and knee arthroplasty. J Orthop Sci 15(6):790–794
Dewan PA et al (1987) The use of an iodophor-impregnated plastic incise drape in abdominal surgery–a controlled clinical trial. Aust N Z J Surg 57(11):859–863
Dimick JB, Lipsett PA, Kostuik JP (2000) Spine update: antimicrobial prophylaxis in spine surgery: basic principles and recent advances. Spine 25(19):2544–2548
Dirschl DR, Wilson FC (1991) Topical antibiotic irrigation in the prophylaxis of operative wound infections in orthopedic surgery. Orthop Clin North Am 22(3):419–426
Edwards JP et al (2012) Wound protectors reduce surgical site infection: a meta-analysis of randomized controlled trials. Ann Surg 256(1):53–59
Eedy DJ, McMillan JC, Bingham EA (1990) Anaphylactic reactions to topical antibiotic combinations. Postgrad Med J 66(780):858–859
Eggers MD, Fang L, Lionberger DR (2011) A comparison of wound closure techniques for total knee arthroplasty. J Arthroplasty 26(8):1251–1258.e1–4
Eklund AE, Tunevall TG (1987) Prevention of postoperative wound infection after appendectomy by local application of tinidazole: a double-blind study. World J Surg 11(2):263–266
El-Gazzar Y et al (2013) The use of dermabond® as an adjunct to wound closure after total knee arthroplasty: examining immediate post-operative wound drainage. J Arthroplasty 28(4):553–556
Erdmann S, Hertl M, Merk HF (1999) Allergic contact dermatitis from povidone-iodine. Contact Dermatitis 40(6):331–332
Evans RP (2011) Current concepts for clean air and total joint arthroplasty: laminar airflow and ultraviolet radiation: a systematic review. Clin Orthop Relat Res 469(4):945–953
Fairclough JA et al (1983) The contaminated skin-knife. A surgical myth. J Bone Joint Surg Br 65(2):210
Fairclough JA, Johnson D, Mackie I (1986) The prevention of wound contamination by skin organisms by the pre-operative application of an iodophor impregnated plastic adhesive drape. J Int Med Res 14(2):105–109
Falk-Brynhildsen K et al (2013) Bacterial colonization of the skin following aseptic preoperative preparation and impact of the use of plastic adhesive drapes. Biol Res Nurs 15(2):242–248
Farnell MB et al (1986) Closure of abdominal incisions with subcutaneous catheters. A prospective randomized trial. Arch Surg 121(6):641–648
Fawley WN et al (2006) Surveillance for mupirocin resistance following introduction of routine peri-operative prophylaxis with nasal mupirocin. J Hosp Infect 62(3):327–332
Garibaldi RA et al (1986) Comparison of nonwoven and woven gown and drape fabric to prevent intraoperative wound contamination and postoperative infection. Am J Surg 152(5):505–509
Garibaldi RA, Cushing D, Lerer T (1991a) Predictors of intraoperative-acquired surgical wound infections. J Hosp Infect 18(Suppl A):289–298
Garibaldi RA, Cushing D, Lerer T (1991b) Risk factors for postoperative infection. Am J Med 91(3B):158S–163S
Gelman ML, Frazier CH, Chandler HP (1979) Acute renal failure after total hip replacement. J Bone Joint Surg Am 61(5):657–660
Gheorghe A et al (2012) Systematic review of the clinical effectiveness of wound-edge protection devices in reducing surgical site infection in patients undergoing open abdominal surgery. Ann Surg 255(6):1017–1029
Gilliam DL, Nelson CL (1990) Comparison of a one-step iodophor skin preparation versus traditional preparation in total joint surgery. Clin Orthop Relat Res 250:258–260
Givissis P et al (2008) Suction during orthopaedic surgery. How safe is the suction tip? Acta Orthop Belg 74(4):531–533
Glait SA et al (2011) Is repetitive intraoperative splash basin use a source of bacterial contamination in total joint replacement? Orthopedics 34(9):e546–e549
González Della Valle A et al (2004) No need for routine closed suction drainage in elective arthroplasty of the hip: a prospective randomized trial in 104 operations. Acta Orthop Scand 75(1):30–33
González Della Valle A, Padgett DE, Salvati EA (2005) Preoperative planning for primary total hip arthroplasty. J Am Acad Orthop Surg 13(7):455–462
González Della Valle A et al (2006) Prevalence of infection in bilateral total hip arthroplasty: a comparison of single-stage 565 bilateral procedures performed with 1 or 2 sets of instruments. J Arthroplasty 21(2):157–160
Grabe N et al (1985) The contaminated skin-knife–fact or fiction. J Hosp Infect 6(3):252–256
Greenough CG (1986) An investigation into contamination of operative suction. J Bone Joint Surg Br 68(1):151–153
Greig J et al (1987) Wound sepsis after colorectal surgery: the effect of cefotetan lavage. Chemioterapia 6(2 Suppl):595–596
Han CD et al (2013) A randomized prospective study of glove perforation in orthopaedic surgery: is a thick glove more effective? J Arthroplasty 28(10):1878–1881
Hart D (1960) Bactericidal ultraviolet radiation in the operating room. Twenty-nine-year study for control of infections. J Am Med Assoc 172:1019–1028
Hester RA, Nelson CL, Harrison S (1992) Control of contamination of the operative team in total joint arthroplasty. J Arthroplasty 7(3):267–269
Hooper GJ et al (2011) Does the use of laminar flow and space suits reduce early deep infection after total hip and knee replacement?: the ten-year results of the New Zealand Joint Registry. J Bone Joint Surg Br 93(1):85–90
Howell JM, Dhindsa HS et al (1993a) Effect of scrubbing and irrigation on staphylococcal and streptococcal counts in contaminated lacerations. Antimicrob Agents Chemother 37(12):2754–2755
Howell JM, Stair TO et al (1993b) The effect of scrubbing and irrigation with normal saline, povidone iodine, and cefazolin on wound bacterial counts in a guinea pig model. Am J Emerg Med 11(2):134–138
Hussein JR et al (2001) Use of light handles in the laminar flow operating theatre–is it a cause of bacterial concern? Ann R Coll Surg Engl 83(5):353–354
Jacobson C et al (2005) Prevention of wound contamination using DuraPrep solution plus Ioban 2 drapes. Clin Orthop Relat Res 439:32–37
Jeske H-C et al (2007) Bacterial contamination of anaesthetists’ hands by personal mobile phone and fixed phone use in the operating theatre. Anaesthesia 62(9):904–906
Kalmeijer MD et al (2000) Nasal carriage of staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery. Infect Control Hosp Epidemiol 21(5):319–323
Kalteis T et al (2007) An experimental comparison of different devices for pulsatile high-pressure lavage and their relevance to cement intrusion into cancellous bone. Arch Orthop Trauma Surg 127(10):873–877
Kappstein I et al (1993) Microbiological and economic studies of abbreviated procedures for surgical hand disinfection. Chirurg 64(5):400–405
Kaska SC (2010) A standardized and safe method of sterile field maintenance during intra-operative horizontal plane fluoroscopy. Patient Saf Surg 4(1):20
Kaya I et al (2012) Glove perforation time and frequency in total hip arthroplasty procedures. Acta Orthop Traumatol Turc 46(1):57–60
Khan RJK et al (2006) A comparison of three methods of wound closure following arthroplasty: a prospective, randomised, controlled trial. J Bone Joint Surg Br 88(2):238–242
Kluytmans-Vandenbergh MF, Kluytmans JA, Voss A (2005) Dutch guideline for preventing nosocomial transmission of highly resistant microorganisms. Infection 33(5-6):309–13
Kurz A, Sessler DI, Lenhardt R (1996) Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group. N Engl J Med 334(19):1209–1215
Lee YJ et al (2013) Contamination rates between smart cell phones and non-smart cell phones of healthcare workers. J Hosp Med 8(3):144–147
Legg AJ, Cannon T, Hamer AJ (2012) Do forced air patient-warming devices disrupt unidirectional downward airflow? J Bone Joint Surg Br 94(2):254–256
Lessing MP, Jordens JZ, Bowler IC (1996) When should healthcare workers be screened for methicillin-resistant Staphylococcus aureus? J Hosp Infect 34(3):205–210
Lewis DA, Leaper DJ, Speller DC (1984) Prevention of bacterial colonization of wounds at operation: comparison of iodine-impregnated (“Ioban”) drapes with conventional methods. J Hosp Infect 5(4):431–437
Lidwell OM (1994) Ultraviolet radiation and the control of airborne contamination in the operating room. J Hosp Infect 28(4):245–248
Lidwell OM et al (1982) Effect of ultraclean air in operating rooms on deep sepsis in the joint after total hip or knee replacement: a randomised study. Br Med J (Clin Res Ed) 285(6334):10–14
Lipp A, Edwards P (2005) Disposable surgical face masks: a systematic review. Can Oper Room Nurs J 23(3):20–21, 24–25, 33–38
Lowell JD et al (1980) Ultraviolet radiation and reduction of deep wound infection following hip and knee arthroplasty. Ann N Y Acad Sci 353:285–293
Lynch RJ et al (2009) Measurement of foot traffic in the operating room: implications for infection control. Am J Med Qual 24(1):45–52
Mackintosh CA, Lidwell OM (1980) The evaluation of fabrics in relation to their use as protective garments in nursing and surgery. III. Wet penetration and contact transfer of particles through clothing. J Hyg 85(3):393–403
Maistrelli GL et al (1995) Cement penetration with pulsed lavage versus syringe irrigation in total knee arthroplasty. Clin Orthop Relat Res 312:261–265
Mangram AJ et al (1999) Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control 27(2):97–132; quiz 133–134, discussion 96
McGovern PD et al (2011) Forced-air warming and ultra-clean ventilation do not mix: an investigation of theatre ventilation, patient warming and joint replacement infection in orthopaedics. J Bone Joint Surg Br 93(11):1537–1544
McHugh SM et al (2011) The role of topical antibiotics used as prophylaxis in surgical site infection prevention. J Antimicrob Chemother 66(4):693–701
McHugh SM et al (2014) Surgical attire, practices and their perception in the prevention of surgical site infection. Surgeon 12(1):47–52
Melling AC et al (2001) Effects of preoperative warming on the incidence of wound infection after clean surgery: a randomised controlled trial. Lancet 358(9285):876–880
Miner AL et al (2007) Deep infection after total knee replacement: impact of laminar airflow systems and body exhaust suits in the modern operating room. Infect Control Hosp Epidemiol 28(2):222–226
Miskovsky C, Whiteside LA, White SE (1992) The cemented unicondylar knee arthroplasty. An in vitro comparison of three cement techniques. Clin Orthop Relat Res 284:215–220
Moggio M et al (1979) Wound infections in patients undergoing total hip arthroplasty. Ultraviolet light for the control of airborne bacteria. Arch Surg 114(7):815–823
Mont MA et al (2013) Single-use instrumentation, cutting blocks, and trials decrease contamination during total knee arthroplasty: a prospective comparison of navigated and nonnavigated cases. J Knee Surg 26(4):285–290
Moretti B et al (2009) Active warming systems to maintain perioperative normothermia in hip replacement surgery: a therapeutic aid or a vector of infection? J Hosp Infect 73(1):58–63
Niki Y et al (2007) How much sterile saline should be used for efficient lavage during total knee arthroplasty? Effects of pulse lavage irrigation on removal of bone and cement debris. J Arthroplasty 22(1):95–99
Panahi P et al (2012) Operating room traffic is a major concern during total joint arthroplasty. Clin Orthop Relat Res 470(10):2690–2694
Parker MJ, Roberts CP, Hay D (2004) Closed suction drainage for hip and knee arthroplasty. A meta-analysis. J Bone Joint Surg Am 86-A(6):1146–1152
Parvizi J, Gehrke T (eds) (2013) Proceedings of the international consensus meeting on periprosthetic joint infection. Data Trace Publishing Company, Brooklandville, Maryland
Pedersen AB et al (2010) Risk factors for revision due to infection after primary total hip arthroplasty. A population-based study of 80,756 primary procedures in the Danish Hip Arthroplasty Registry. Acta Orthop 81(5):542–547
Peersman G et al (2006) Prolonged operative time correlates with increased infection rate after total knee arthroplasty. HSS J 2(1):70–72
Perl TM, Golub JE (1998) New approaches to reduce staphylococcus aureus nosocomial infection rates: treating S. aureus nasal carriage. Ann Pharmacother 32(1):S7–S16
Peters FM et al (2012) Improving acetabular cup orientation in total hip arthroplasty by using smartphone technology. J Arthroplasty 27(7):1324–1330
Quraishi ZA et al (1983) Movement of personnel and wound contamination. AORN J 38(1):146–147, 150–156
Rambo WM (1972) Irrigation of the peritoneal cavity with cephalothin. Am J Surg 123(2):192–195
Ridgeway S et al (2005) Infection of the surgical site after arthroplasty of the hip. J Bone Joint Surg Br 87(6):844–850
Ritter MA, Eitzen H et al (1975a) The operating room environment as affected by people and the surgical face mask. Clin Orthop Relat Res 111:147–150
Ritter MA, French ML, Eitzen HE (1975b) Bacterial contamination of the surgical knife. Clin Orthop Relat Res 108:158–160
Ritter MA, Olberding EM, Malinzak RA (2007) Ultraviolet lighting during orthopaedic surgery and the rate of infection. J Bone Joint Surg Am 89(9):1935–1940
Robinson AH et al (1993) Suction tip contamination in the ultraclean-air operating theatre. Ann R Coll Surg Engl 75(4):254–256
Sadat-Ali M et al (2010) Bacterial flora on cell phones of health care providers in a teaching institution. Am J Infect Control 38(5):404–405
Salvati EA et al (1982) Infection rates after 3175 total hip and total knee replacements performed with and without a horizontal unidirectional filtered air-flow system. J Bone Joint Surg Am 64(4):525–535
Salvati EA et al (2003) The infected total hip arthroplasty. Instr Course Lect 52:223–245
Savitz SI et al (1994) Investigations of the bacteriological factors in clean neurosurgical wounds. Neurosurgery 34(3):417–420; discussion 420–421
Schein M et al (1990) Peritoneal lavage in abdominal sepsis. A controlled clinical study. Arch Surg 125(9):1132–1135
Schindler OS, Spencer RF, Smith MD (2006) Should we use a separate knife for the skin? J Bone Joint Surg Br 88(3):382–385
Seeger JB et al (2013) The effect of bone lavage on femoral cement penetration and interface temperature during Oxford unicompartmental knee arthroplasty with cement. J Bone Joint Surg Am 95(1):48–53
Sherman JO, Luck SR, Borger JA (1976) Irrigation of the peritoneal cavity for appendicitis in children: a double-blind study. J Pediatr Surg 11(3):371–374
Siegel JD et al (2007) 2007 guideline for isolation precautions: preventing transmission of infectious agents in health care settings. Am J Infect Control 35(10 Suppl 2):S65–S164
Singh A, Purohit B (2012) Mobile phones in hospital settings: a serious threat to infection. Occup Health Saf 81(3):42–44
Singh D et al (2002) Bacterial contamination of hospital pagers. Infect Control Hosp Epidemiol 23(5):274–276
Skråmm I, Saltytė Benth J, Bukholm G (2012) Decreasing time trend in SSI incidence for orthopaedic procedures: surveillance matters! J Hosp Infect 82(4):243–247
Småbrekke A et al (2004) Operating time and survival of primary total hip replacements: an analysis of 31,745 primary cemented and uncemented total hip replacements from local hospitals reported to the Norwegian Arthroplasty Register 1987–2001. Acta Orthop Scand 75(5):524–532
Smith TO et al (2010) Sutures versus staples for skin closure in orthopaedic surgery: meta-analysis. BMJ 340:c1199
Strange-Vognsen HH, Klareskov B (1988) Bacteriologic contamination of suction tips during hip arthroplasty. Acta Orthop Scand 59(4):410–411
Sutton PM, Greene T, Howell FR (1998) The protective effect of a cut-resistant glove liner. A prospective, randomised trial. J Bone Joint Surg Br 80(3):411–413
Taylor GJ, Bannister GC (1993) Infection and interposition between ultraclean air source and wound. J Bone Joint Surg Br 75(3):503–504
Taylor GJ, Bannister GC, Leeming JP (1995) Wound disinfection with ultraviolet radiation. J Hosp Infect 30(2):85–93
Tumia N, Ashcroft GP (2002) Convection warmers–a possible source of contamination in laminar airflow operating theatres? J Hosp Infect 52(3):171–174
Tunevall TG (1991) Postoperative wound infections and surgical face masks: a controlled study. World J Surg 15(3):383–387; discussion 387–388
Tunevall TG, Jörbeck H (1992) Influence of wearing masks on the density of airborne bacteria in the vicinity of the surgical wound. Eur J Surg 158(5):263–266
Ulger F et al (2009) Are we aware how contaminated our mobile phones with nosocomial pathogens? Ann Clin Microbiol Antimicrob 8(1):7
Ustun C, Cihangiroglu M (2012) Health care workers’ mobile phones: a potential cause of microbial cross-contamination between hospitals and community. J Occup Environ Hyg 9(9):538–542
Walmsley PJ et al (2005) A prospective, randomised, controlled trial of the use of drains in total hip arthroplasty. J Bone Joint Surg Br 87(10):1397–1401
Webster J, Alghamdi AA (2007) Use of plastic adhesive drapes during surgery for preventing surgical site infection. Cochrane Database Syst Rev (4):CD006353
Webster J et al (2010) Use of face masks by non-scrubbed operating room staff: a randomized controlled trial. ANZ J Surg 80(3):169–173
Willis-Owen CA, Konyves A, Martin DK (2010) Factors affecting the incidence of infection in hip and knee replacement: an analysis of 5277 cases. J Bone Joint Surg Br 92(8):1128–1133
Wilson SE (2008) Microbial sealing: a new approach to reducing contamination. J Hosp Infect 70(Suppl 2):11–14
Wymenga AB et al (1992) Perioperative factors associated with septic arthritis after arthroplasty. Prospective multicenter study of 362 knee and 2,651 hip operations. Acta Orthop Scand 63(6):665–671
Zhou X-D et al (2013) Do we really need closed-suction drainage in total hip arthroplasty? A meta-analysis. Int Orthop 37(11):2109–2118
Zink RS, Iaizzo PA (1993) Convective warming therapy does not increase the risk of wound contamination in the operating room. Anesth Analg 76(1):50–53
Zokaie S, White IR, McFadden JD (2011) Allergic contact dermatitis caused by iodophor-impregnated surgical incise drape. Contact Dermatitis 65(5):309
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This work was partially funded by the generous donation of Mr. Glenn Bergenfield and The Sidney Milton and Leoma Simon Foundation.
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Schnaser, E., Della Valle, A.G. (2015). Environmental Factors and Infection in Total Joint Replacement Surgery. In: Baldini, A., Caldora, P. (eds) Perioperative Medical Management for Total Joint Arthroplasty. Springer, Cham. https://doi.org/10.1007/978-3-319-07203-6_20
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