Skip to main content

Individualised Treatment

Patient-Related Factors: Patients’ Preference

  • Chapter
  • First Online:
  • 2114 Accesses

Abstract

As a fundamental part of the multidisciplinary treatment in colorectal cancer, treatment guidelines and decision making on treatment strategy in multidisciplinary teams have evolved. The selection of treatment strategy is primarily based on an accurate staging of the disease by means of achieving a precise cTNM stage prior to treatment. In order to be able to decide on treatment strategy in a specific patient, awareness of the impact of patient-related factors, most importantly comorbidity and physiological age, is essential. The POSSUM score, an objective model for risk prediction in surgery, and the concept of comprehensive geriatric assessment, a multidimensional assessment tool for evaluation of elderly patients, can be of help in this process. Based on this evaluation and on the patient’s preference, an optimal, individualised treatment strategy for the specific patient can be achieved.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   179.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Reza MM, Blasco JA, Andradas E, Cantero R, Mayol J. Systematic review of laparoscopic versus open surgery for colorectal cancer. Br J Surg. 2006;93:921–8.

    Article  CAS  PubMed  Google Scholar 

  2. Cunningham D, Atkin W, Lenz HJ, Lynch HT, Minsky B, Nordlinger B, et al. Colorectal cancer. Lancet. 2010;375:1030–47.

    Article  PubMed  Google Scholar 

  3. Eriksen MT, Wibe A, Hestvik UE, Haffner J, Wiig JN. Surgical treatment of primary locally advanced rectal cancer in Norway. Eur J Surg Oncol. 2006;32:174–80.

    Article  CAS  PubMed  Google Scholar 

  4. Baatrup G, Endreseth BH, Isaksen V, Kjellmo Å, Tveit KM, Nesbakken A. Preoperative staging and treatment options in T1 rectal adenocarcinoma. Acta Oncol. 2009;48:328–42.

    Article  PubMed  Google Scholar 

  5. Cahill RA, Leroy J, Marescaux J. Localized resection of colon cancer. Surg Oncol. 2009;18:334–42.

    Article  CAS  PubMed  Google Scholar 

  6. Mahmoud N, Bullard DK. Metastasectomy for stage IV colorectal cancer. Dis Colon Rectum. 2010;53:1080–92.

    Article  PubMed  Google Scholar 

  7. Goldberg RM, Rothenberg ML, Van Cutsem E, Benson III AB, Blanke CD, Diasio RB, et al. The continuum of care: a paradigm for the management of metastatic colorectal cancer. Oncologist. 2007;12:38–50.

    Article  PubMed  Google Scholar 

  8. UICC. TNM classification of malignant tumours. 5th ed. New York: Wiley; 1997.

    Google Scholar 

  9. Nasjonalt handlingsprogram med retningslinjer for diagnostikk, behandling og oppfølging av kreft i tykk og endetarm. http://ngicg.no/handlingsprogram/nasjonale_handlingsprogrammer/content_1/filelist_ee59ae57-c583-41bb-8e91-ac712e639640/1395777852047/nasjonalt_handlingsprogram_for_tykk_og_endetarmskreft.pdf.

  10. Keats AS. The ASA, classification of physical status – a recapitulation. Anesthesiology. 1978;49:233–6.

    Article  CAS  PubMed  Google Scholar 

  11. Copeland GP, Jones D, Walters M. POSSUM: a scoring system for surgical audit. Br J Surg. 1991;78:356–60.

    Google Scholar 

  12. Prytherch DR, Whiteley MS, Higgins B, Weaver PC, Prout WG, Powell SJ. POSSUM and Portsmouth POSSUM for predicting mortality. Physiological and operative severity score for the enumeration of mortality and morbidity. Br J Surg. 1998;85:1217–20.

    Article  CAS  PubMed  Google Scholar 

  13. Tekkis PP, Kessaris N, Kocher HM, Poloniecki JD, Lyttle J, Windsor ACJ. Evaluation of POSSUM and P-POSSUM scoring systems in patients undergoing colorectal surgery. Br J Surg. 2003;90:340–5.

    Article  CAS  PubMed  Google Scholar 

  14. Tekkis PP, Prytherch DR, Kocher HM, Senapati A, Poloniecki JD, Stamatakis JD, et al. Development of a dedicated risk-adjustment scoring system for colorectal surgery (colorectal POSSUM). Br J Surg. 2004;91:1174–82.

    Article  CAS  PubMed  Google Scholar 

  15. Risk Prediction in Surgery. http://www.riskprediction.org.uk

  16. Bromage SJ, Cunliffe WJ. Validation of the CR-POSSUM risk-adjusted scoring system for major colorectal cancer surgery in a single center. Dis Colon Rectum. 2007;50:192–6.

    Article  PubMed  Google Scholar 

  17. Senagore AJ, Warmuth AJ, Delaney CP, Tekkis PP, Fazio VW. POSSUM, p-POSSUM, and Cr-POSSUM: Implementation issues in a United States care system for prediction of outcome for colon cancer resection. Dis Colon Rectum. 2004;47:1435–41.

    Article  PubMed  Google Scholar 

  18. Chandra A, Mangam S, Marzouk D. A review of risk scoring systems utilised in patients undergoing gastrointestinal surgery. J Gastrointest Surg. 2009;13:1529–38.

    Article  PubMed  Google Scholar 

  19. Cancer Registry of Norway. Cancer in Norway 2005; 2006.

    Google Scholar 

  20. Endreseth BH, Romundstad P, Myrvold HE, Bjerkeset T, Wibe A, Norwegian Rectal Cancer Group. Rectal cancer in the elderly. Colorectal Dis. 2006;8:471–9.

    Article  CAS  PubMed  Google Scholar 

  21. Van Leeuwen BL, Påhlman L, Gunnarson U, Sjovall A, Martling A. The effect of age and gender on outcome after treatment for colon carcinoma. A population-based study in the Uppsala and Stockholm region. Crit Rev Oncol Hematol. 2008;67:229–36.

    Article  PubMed  Google Scholar 

  22. Pallis AG, Papamichael D, Audisio R, Peeters M, Folprecht G, Lacombe D, Van Cutsem E. EORTC elderly task force experts opinion for the treatment of colon cancer in older patients. Cancer Treat Rev. 2010;36:83–90.

    Article  CAS  PubMed  Google Scholar 

  23. Abir F, Alva S, Longo WE. The management of rectal cancer in the elderly. Surg Oncol. 2004;13:223–4.

    Article  PubMed  Google Scholar 

  24. Golfinopoulus V, Pentheroudakis G, Pavlidis N. Treatment of colorectal cancer in the elderly: a review of the literature. Cancer Treat Rev. 2006;32:1–8.

    Article  Google Scholar 

  25. Ugolini G, Rosati G, Montroni I, Zanotti S, Manaresi A, Giampaolo L, et al. Can elderly patients with colorectal cancer tolerate planned surgical treatment? A practical approach to a common dilemma. Colorectal Dis. 2009;11:750–5.

    Article  CAS  PubMed  Google Scholar 

  26. Kristjansson SR, Nesbakken A, Jordhøy MS, Skovlund E, Audisio RA, Johannesen HO, et al. Comprehensive geriatric assessment can predict complications in elderly patients after elective surgery for colorectal cancer: a prospective observational cohort study. Crit Rev Oncol Hematol. 2009. doi:10.1016/j.critrevonc.2009.11.002.

    PubMed  Google Scholar 

  27. Tei M, Ikeda M, Haraguchi N, Takemasa I, Mizushima T, Ishii H, et al. Postoperative complications in elderly patients with colorectal cancer. Comparison of open and laparoscopic surgical procedures. Surg Laparosc Endosc Percutan Tech. 2009;19:488–92.

    Article  PubMed  Google Scholar 

  28. Menon KV, Al-Mukhtar A, Aldouri A, Prasad RK, Lodge PA, Toogood GJ. Outcomes after major hepatectomy in elderly patients. J Am Coll Surg. 2006;203:677–83.

    Article  PubMed  Google Scholar 

  29. Pfannschmidt J, Dienemann H, Hoffmann H. Surgical resection of pulmonary metastases from colorectal cancer: a systematic review of published series. Ann Torac Surg. 2007;84:324–38.

    Article  Google Scholar 

  30. Iversen LH, Bulow S, Christensen IJ, Laurberg S, Harling H. on behalf of the Danish Colorectal cancer Group. Postoperative medical complications are the main cause of early death after emergency surgery for colonic cancer. Br J Surg. 2008;95:1012–9.

    Article  CAS  PubMed  Google Scholar 

  31. Dionigi G, Villa F, Rovera F, Boni L, Carrafiello G, Annoni M, et al. Colonic stenting for malignant disease: review of the literature. Surg Oncol. 2007;16:S153–5.

    Article  PubMed  Google Scholar 

  32. Eriksen MT, Wibe A, Norstein J, Haffner J, Wiig JN. on behalf of the Norwegian Rectal Cancer Group. Anastomotic leakage following routine mesorectal excision for rectal cancer in a national cohort of patients. Colorectal Dis. 2005;7:51–7.

    Article  CAS  PubMed  Google Scholar 

  33. Sanoff HK, Bleiberg H, Goldberg RM. Managing older patients with colorectal cancer. J Clin Oncol. 2007;25:1930–5.

    Article  Google Scholar 

  34. Horiot J-C. Radiation therapy and the geriatric oncology patient. J Clin Oncol. 2007;25:1891–7.

    Article  Google Scholar 

  35. Balducci L, Colloca G, Cesari M, Gambassi G. Assessment and treatment of elderly patients with cancer. Surg Oncol. 2009. doi:10.1016/j.suronc.2009.11.008.

    PubMed  Google Scholar 

  36. Balducci L, Extermann M. Management of cancer in the older person: a practical approach. Oncologist. 2000;5:224–37.

    Article  CAS  PubMed  Google Scholar 

  37. Extermann M, Aapro M, Bernabei R, Cohen HJ, Droz JP, Lichtman S, et al. Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol. 2005;55:241–52.

    Article  PubMed  Google Scholar 

  38. Girre V, Falcou MC, Gisselbrecht M, Gridel G, Mosseri V, Bouleuc C, et al. Does a geriatric oncology consultation modify the cancer treatment plan for elderly patients? J Gerontol A Biol Sci Med Sci. 2008;63:724–30.

    Article  PubMed  Google Scholar 

  39. Redmond K. Assessing patient’s needs and preferences in the management of advanced colorectal cancer. Br J Cancer. 1998;77 Suppl 2:5–7.

    Article  PubMed Central  PubMed  Google Scholar 

  40. Zafar SY, Alexander SC, Weinfurt KP, Schulman KA, Abernethy AP. Decision making and quality of life in the treatment of cancer: a review. Support Care Cancer. 2009;17:117–27.

    Article  PubMed  Google Scholar 

  41. Harrison JD, Solomon MJ, Young JM, Meagher A, Butow P, Salkeld G, et al. Patient and physician preferences for surgical and adjuvant treatment options for rectal cancer. Arch Surg. 2008;143:389–94.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Birger Henning Endreseth MD, PhD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Endreseth, B.H. (2015). Individualised Treatment. In: Baatrup, G. (eds) Multidisciplinary Treatment of Colorectal Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-06142-9_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-06142-9_27

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-06141-2

  • Online ISBN: 978-3-319-06142-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics