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Polymeric Cryogels pp 199–222Cite as

Cryogels via UV Irradiation

Part of the Advances in Polymer Science book series (POLYMER,volume 263)

Abstract

An effective and facile method for the synthesis of chemically crosslinked supermacroporous polymer cryogels based on UV irradiation is reviewed. The influence of key factors like the irradiation dose, temperature of freezing, concentration of polymer or monomer precursor, molar mass of polymer precursor, and the type and amount of the photoinitiator on crosslinking efficiency is discussed. The versatility of the method for preparation of a large number of biocompatible, biodegradable, and/or stimuli-responsive cryogels is demonstrated. Examples include some specific properties of well-investigated polyacrylamide (PAAm) and poly(N-isopropylacrylamide) (PNIPAAm) cryogels obtained by photocrosslinking as well as novel cryogels based on cellulose derivatives, hydrophobically modified polyglycidol (PGL), and ethoxytriethyleneglycol acrylate (ETEGA). Part of this review is focused on the applicability of supermacroporous cryogels as carriers of different species such as drugs, enzymes, nanoparticles, and cells immobilized in either cryogel walls (polymer matrix) or interconnected pores.

Keywords

  • UV irradiation
  • Photocrosslinking
  • Cellulose derivatives
  • Stimuli-responsive cryogels
  • Carriers

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  • DOI: 10.1007/978-3-319-05846-7_5
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Abbreviations

AAm:

Acrylamide

AgNPs:

Silver nanoparticles

BBTMAC:

(4-Benzoylbenzyl)trimethylammonium chloride

BisAAm:

N,N′-methylenebisacrylamide

CNT:

Carbon nanotube

DMAEMA:

2-(Dimetylamino)ethyl methacrylate

DS:

Degree of swelling

ETEGA:

Ethoxytriethyleneglycol acrylate

GF:

Gel fraction

HEC:

2-Hydroxyethylcellulose

HEMA:

2-Hydroxyethyl methacrylate

HPC:

Hydroxypropylcellulose

HPMC:

(Hydroxypropyl)methylcellulose

LCST:

Lower critical solution temperature

MC:

Methylcellulose

NIPAAm:

N-Isopropylacrylamide

OEGMA:

Oligo(ethyleneglycol) methacrylate

PAAm:

Polyacrylamide

PEGDA:

Poly(ethylene glycol) diacrylate

PEO:

Poly(ethylene oxide)

PETEGA:

Poly(ethoxytriethyleneglycol) acrylate

PGL:

Polyglycidol

PHEMA:

Poly(2-hydroxyethyl methacrylate)

PNIPAAm:

Poly(N-isopropylacrylamide)

T VPT :

Temperature of volume phase transition

VCL:

Vinyl caprolactam

UV:

Ultraviolet

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Authors and Affiliations

  1. Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev Str. 103 A, Sofia, 1113, Bulgaria

    Petar D. Petrov & Christo B. Tsvetanov

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  1. Petar D. Petrov
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  2. Christo B. Tsvetanov
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Correspondence to Petar D. Petrov .

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Editors and Affiliations

  1. Department of Chemistry, Istanbul Technical University, Istanbul, Turkey

    Oguz Okay

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Petrov, P.D., Tsvetanov, C.B. (2014). Cryogels via UV Irradiation. In: Okay, O. (eds) Polymeric Cryogels. Advances in Polymer Science, vol 263. Springer, Cham. https://doi.org/10.1007/978-3-319-05846-7_5

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