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Introduction: Childhood Leukemia

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Etiology of Acute Leukemias in Children

Abstract

Childhood leukemia is universal, with the same molecular mechanisms at play in children of different genetic and environmental backgrounds. Leukemia is regional as well, and the factors that influence its occurrence and outcome can be affected by ethnic, environmental, geographic, and social circumstances. Childhood leukemia is also unique for every person, such that two individuals with apparently the same disease can respond in a different way to the same treatment and exhibit a different toxicity pattern.

As an introduction to this book, this chapter contains an overview of childhood acute leukemias, covering the relevant aspects of the two main subtypes that occur in pediatric patients, with the aim of providing a basis for the understanding of this heterogeneous group of malignancies.

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  1. Hematology and Oncology Department, Hospital Infantil de Mexico Federico Gómez, Calle Dr. Márquez No 162 Colonia Doctores, C.P. 06720, México, D.F., Mexico

    Aurora Medina-Sanson

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  1. Coordinación de Investigación en Salud, Instituto Mexicano del Seguro Social, City, Distrito Federal, Mexico

    Juan Manuel Mejía-Aranguré

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Medina-Sanson, A. (2016). Introduction: Childhood Leukemia. In: Mejía-Aranguré, J. (eds) Etiology of Acute Leukemias in Children. Springer, Cham. https://doi.org/10.1007/978-3-319-05798-9_1

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